UniProtKB - P54763 (EPHB2_MOUSE)
Ephrin type-B receptor 2
Ephb2
Functioni
Catalytic activityi
- EC:2.7.10.1PROSITE-ProRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 653 | ATPPROSITE-ProRule annotation | 1 | |
Active sitei | 746 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 627 – 635 | ATPPROSITE-ProRule annotation | 9 |
GO - Molecular functioni
- amyloid-beta binding Source: ARUK-UCL
- ATP binding Source: UniProtKB-KW
- axon guidance receptor activity Source: MGI
- ephrin receptor activity Source: MGI
- identical protein binding Source: IntAct
- protein-containing complex binding Source: ARUK-UCL
- protein tyrosine kinase activity Source: UniProtKB
- signaling receptor activity Source: MGI
- signaling receptor binding Source: MGI
- transmembrane-ephrin receptor activity Source: UniProtKB
- transmembrane receptor protein tyrosine kinase activity Source: GO_Central
GO - Biological processi
- angiogenesis Source: UniProtKB
- animal organ morphogenesis Source: MGI
- axonal fasciculation Source: UniProtKB
- axon guidance Source: MGI
- camera-type eye morphogenesis Source: MGI
- cell morphogenesis Source: MGI
- central nervous system projection neuron axonogenesis Source: MGI
- commissural neuron axon guidance Source: UniProtKB
- corpus callosum development Source: UniProtKB
- dendritic spine development Source: UniProtKB
- dendritic spine morphogenesis Source: MGI
- ephrin receptor signaling pathway Source: UniProtKB
- inactivation of MAPKK activity Source: ARUK-UCL
- inner ear morphogenesis Source: UniProtKB
- learning Source: MGI
- learning or memory Source: ARUK-UCL
- multicellular organism development Source: GO_Central
- negative regulation of axonogenesis Source: MGI
- negative regulation of ERK1 and ERK2 cascade Source: ARUK-UCL
- negative regulation of NMDA glutamate receptor activity Source: ARUK-UCL
- negative regulation of protein phosphorylation Source: ARUK-UCL
- negative regulation of Ras protein signal transduction Source: ARUK-UCL
- neuron projection retraction Source: ARUK-UCL
- optic nerve morphogenesis Source: MGI
- peptidyl-tyrosine phosphorylation Source: UniProtKB
- phosphorylation Source: UniProtKB
- positive regulation of gene expression Source: MGI
- positive regulation of kinase activity Source: GO_Central
- positive regulation of long-term neuronal synaptic plasticity Source: MGI
- positive regulation of long-term synaptic potentiation Source: ARUK-UCL
- positive regulation of NMDA glutamate receptor activity Source: ARUK-UCL
- positive regulation of protein localization to plasma membrane Source: MGI
- positive regulation of synapse assembly Source: UniProtKB
- positive regulation of synaptic plasticity Source: ARUK-UCL
- postsynaptic membrane assembly Source: MGI
- protein phosphorylation Source: MGI
- regulation of axonogenesis Source: MGI
- regulation of blood coagulation Source: UniProtKB
- regulation of body fluid levels Source: UniProtKB
- regulation of neuronal synaptic plasticity Source: MGI
- retinal ganglion cell axon guidance Source: MGI
- roof of mouth development Source: UniProtKB
- transmembrane receptor protein tyrosine kinase signaling pathway Source: MGI
- trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission Source: SynGO
- urogenital system development Source: UniProtKB
Keywordsi
Molecular function | Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase |
Biological process | Neurogenesis |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
Reactomei | R-MMU-2682334, EPH-Ephrin signaling R-MMU-3928662, EPHB-mediated forward signaling R-MMU-3928664, Ephrin signaling R-MMU-3928665, EPH-ephrin mediated repulsion of cells |
Names & Taxonomyi
Protein namesi | Recommended name: Ephrin type-B receptor 2Curated (EC:2.7.10.1)Alternative name(s): Neural kinase Nuk receptor tyrosine kinase Tyrosine-protein kinase receptor EPH-3 Tyrosine-protein kinase receptor SEK-3 Cleaved into the following 2 chains: EphB2/CTF11 Publication EphB2/CTF21 Publication |
Gene namesi | |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:99611, Ephb2 |
Subcellular locationi
Plasma membrane
Other locations
Nucleus
- nucleoplasm Source: MGI
Plasma Membrane
- integral component of plasma membrane Source: UniProtKB
- plasma membrane Source: MGI
Other locations
- axon Source: UniProtKB
- dendrite Source: UniProtKB
- glutamatergic synapse Source: MGI
- neuron projection Source: GO_Central
- neuronal cell body Source: MGI
- receptor complex Source: GO_Central
- synapse Source: UniProtKB
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 19 – 543 | ExtracellularSequence analysisAdd BLAST | 525 | |
Transmembranei | 544 – 564 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 565 – 986 | CytoplasmicSequence analysisAdd BLAST | 422 |
Keywords - Cellular componenti
Cell membrane, Cell projection, MembranePathology & Biotechi
Disruption phenotypei
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 596 | Y → F: No loss of interaction with SPSB4; when associated with F-602. 1 Publication | 1 | |
Mutagenesisi | 602 | Y → F: No loss of interaction with SPSB4; when associated with F-596. 1 Publication | 1 |
Chemistry databases
ChEMBLi | CHEMBL5961 |
GuidetoPHARMACOLOGYi | 1831 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 18 | Sequence analysisAdd BLAST | 18 | |
ChainiPRO_0000016828 | 19 – 986 | Ephrin type-B receptor 2Sequence analysisAdd BLAST | 968 | |
ChainiPRO_0000445963 | 536 – 986 | EphB2/CTF11 PublicationAdd BLAST | 451 | |
ChainiPRO_0000445964 | 562 – 986 | EphB2/CTF21 PublicationAdd BLAST | 425 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 62 ↔ 184 | 1 Publication | ||
Disulfide bondi | 97 ↔ 107 | 1 Publication | ||
Glycosylationi | 265 | N-linked (GlcNAc...) asparagine1 Publication | 1 | |
Glycosylationi | 336 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 428 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 482 | N-linked (GlcNAc...) asparagine1 Publication | 1 |
Post-translational modificationi
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sitei | 535 – 536 | Cleavage; by a metalloproteinase1 Publication | 2 | |
Sitei | 561 – 562 | Cleavage; by gamma-secretase/PS11 Publication | 2 |
Keywords - PTMi
Disulfide bond, Glycoprotein, Phosphoprotein, Ubl conjugationProteomic databases
jPOSTi | P54763 |
MaxQBi | P54763 |
PaxDbi | P54763 |
PRIDEi | P54763 |
PTM databases
GlyGeni | P54763, 4 sites |
iPTMneti | P54763 |
PhosphoSitePlusi | P54763 |
SwissPalmi | P54763 |
Expressioni
Tissue specificityi
Developmental stagei
Gene expression databases
Bgeei | ENSMUSG00000028664, Expressed in floor plate of midbrain and 320 other tissues |
ExpressionAtlasi | P54763, baseline and differential |
Interactioni
Subunit structurei
Heterotetramer upon binding of the ligand (PubMed:11780069). The heterotetramer is composed of an ephrin dimer and a receptor dimer (PubMed:11780069).
Interacts (via PDZ-binding motif) with GRIP1 and PICK1 (via PDZ domain) (PubMed:9883737).
Interacts with ARHGEF15; mediates ARHGEF15 phosphorylation, ubiquitination and degradation by the proteasome (PubMed:21029865).
Interacts with AQP1; involved in endolymph production in the inner ear (PubMed:10839360).
Interacts with EFNA5 (PubMed:15107857).
Interacts with SPSB1 (By similarity).
Interacts with SPSB4 (PubMed:28931592).
Interacts with SH2D3C (PubMed:10542222).
By similarity7 PublicationsBinary interactionsi
Hide detailsP54763
GO - Molecular functioni
- identical protein binding Source: IntAct
- signaling receptor binding Source: MGI
Protein-protein interaction databases
CORUMi | P54763 |
DIPi | DIP-34917N |
IntActi | P54763, 14 interactors |
MINTi | P54763 |
STRINGi | 10090.ENSMUSP00000101472 |
Chemistry databases
BindingDBi | P54763 |
Miscellaneous databases
RNActi | P54763, protein |
Structurei
Secondary structure
3D structure databases
BMRBi | P54763 |
SMRi | P54763 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P54763 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 20 – 202 | Eph LBDPROSITE-ProRule annotationAdd BLAST | 183 | |
Domaini | 324 – 434 | Fibronectin type-III 1PROSITE-ProRule annotationAdd BLAST | 111 | |
Domaini | 435 – 530 | Fibronectin type-III 2PROSITE-ProRule annotationAdd BLAST | 96 | |
Domaini | 621 – 884 | Protein kinasePROSITE-ProRule annotationAdd BLAST | 264 | |
Domaini | 913 – 977 | SAMPROSITE-ProRule annotationAdd BLAST | 65 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 984 – 986 | PDZ-binding | 3 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 184 – 321 | Cys-richAdd BLAST | 138 |
Sequence similaritiesi
Keywords - Domaini
Repeat, Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0196, Eukaryota |
GeneTreei | ENSGT00940000155503 |
InParanoidi | P54763 |
OMAi | YYYESDF |
OrthoDBi | 933071at2759 |
TreeFami | TF315608 |
Family and domain databases
CDDi | cd10477, EphR_LBD_B2, 1 hit cd00063, FN3, 2 hits |
Gene3Di | 1.10.150.50, 1 hit 2.60.120.260, 1 hit 2.60.40.10, 2 hits |
InterProi | View protein in InterPro IPR027936, Eph_TM IPR034238, EphB2_rcpt_lig-bd IPR001090, Ephrin_rcpt_lig-bd_dom IPR003961, FN3_dom IPR036116, FN3_sf IPR008979, Galactose-bd-like_sf IPR009030, Growth_fac_rcpt_cys_sf IPR013783, Ig-like_fold IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR001660, SAM IPR013761, SAM/pointed_sf IPR001245, Ser-Thr/Tyr_kinase_cat_dom IPR011641, Tyr-kin_ephrin_A/B_rcpt-like IPR008266, Tyr_kinase_AS IPR020635, Tyr_kinase_cat_dom IPR016257, Tyr_kinase_ephrin_rcpt IPR001426, Tyr_kinase_rcpt_V_CS |
Pfami | View protein in Pfam PF14575, EphA2_TM, 1 hit PF01404, Ephrin_lbd, 1 hit PF07699, Ephrin_rec_like, 1 hit PF00041, fn3, 2 hits PF07714, PK_Tyr_Ser-Thr, 1 hit PF00536, SAM_1, 1 hit |
PIRSFi | PIRSF000666, TyrPK_ephrin_receptor, 1 hit |
PRINTSi | PR00109, TYRKINASE |
SMARTi | View protein in SMART SM00615, EPH_lbd, 1 hit SM01411, Ephrin_rec_like, 1 hit SM00060, FN3, 2 hits SM00454, SAM, 1 hit SM00219, TyrKc, 1 hit |
SUPFAMi | SSF47769, SSF47769, 1 hit SSF49265, SSF49265, 1 hit SSF49785, SSF49785, 1 hit SSF56112, SSF56112, 1 hit SSF57184, SSF57184, 1 hit |
PROSITEi | View protein in PROSITE PS51550, EPH_LBD, 1 hit PS50853, FN3, 2 hits PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00109, PROTEIN_KINASE_TYR, 1 hit PS00790, RECEPTOR_TYR_KIN_V_1, 1 hit PS00791, RECEPTOR_TYR_KIN_V_2, 1 hit PS50105, SAM_DOMAIN, 1 hit |
s (3+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MAVRRLGAAL LLLPLLAAVE ETLMDSTTAT AELGWMVHPP SGWEEVSGYD
60 70 80 90 100
ENMNTIRTYQ VCNVFESSQN NWLRTKFIRR RGAHRIHVEM KFSVRDCSSI
110 120 130 140 150
PSVPGSCKET FNLYYYEADF DLATKTFPNW MENPWVKVDT IAADESFSQV
160 170 180 190 200
DLGGRVMKIN TEVRSFGPVS RNGFYLAFQD YGGCMSLIAV RVFYRKCPRI
210 220 230 240 250
IQNGAIFQET LSGAESTSLV AARGSCIANA EEVDVPIKLY CNGDGEWLVP
260 270 280 290 300
IGRCMCKAGF EAVENGTVCR GCPSGTFKAN QGDEACTHCP INSRTTSEGA
310 320 330 340 350
TNCVCRNGYY RADLDPLDMP CTTIPSAPQA VISSVNETSL MLEWTPPRDS
360 370 380 390 400
GGREDLVYNI ICKSCGSGRG ACTRCGDNVQ YAPRQLGLTE PRIYISDLLA
410 420 430 440 450
HTQYTFEIQA VNGVTDQSPF SPQFASVNIT TNQAAPSAVS IMHQVSRTVD
460 470 480 490 500
SITLSWSQPD QPNGVILDYE LQYYEKELSE YNATAIKSPT NTVTVQGLKA
510 520 530 540 550
GAIYVFQVRA RTVAGYGRYS GKMYFQTMTE AEYQTSIKEK LPLIVGSSAA
560 570 580 590 600
GLVFLIAVVV IAIVCNRRGF ERADSEYTDK LQHYTSGHMT PGMKIYIDPF
610 620 630 640 650
TYEDPNEAVR EFAKEIDISC VKIEQVIGAG EFGEVCSGHL KLPGKREIFV
660 670 680 690 700
AIKTLKSGYT EKQRRDFLSE ASIMGQFDHP NVIHLEGVVT KSTPVMIITE
710 720 730 740 750
FMENGSLDSF LRQNDGQFTV IQLVGMLRGI AAGMKYLADM NYVHRDLAAR
760 770 780 790 800
NILVNSNLVC KVSDFGLSRF LEDDTSDPTY TSALGGKIPI RWTAPEAIQY
810 820 830 840 850
RKFTSASDVW SYGIVMWEVM SYGERPYWDM TNQDVINAIE QDYRLPPPMD
860 870 880 890 900
CPSALHQLML DCWQKDRNHR PKFGQIVNTL DKMIRNPNSL KAMAPLSSGI
910 920 930 940 950
NLPLLDRTIP DYTSFNTVDE WLEAIKMGQY KESFANAGFT SFDVVSQMMM
960 970 980
EDILRVGVTL AGHQKKILNS IQVMRAQMNQ IQSVEV
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketF6Q4H2 | F6Q4H2_MOUSE | Ephrin type-B receptor 2 | Ephb2 | 276 | Annotation score: |
Sequence cautioni
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_057932 | 476 | K → KQ in isoform 4. Curated | 1 | |
Alternative sequenceiVSP_057933 | 566 | N → NR in isoform 2. 1 Publication | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | JH584273 Genomic DNA No translation available. BC043088 mRNA Translation: AAH43088.2 BC062924 mRNA Translation: AAH62924.1 Different initiation. L25890 mRNA Translation: AAA72411.1 Different initiation. X76011 mRNA Translation: CAA53598.1 |
RefSeqi | NP_001277682.1, NM_001290753.2 [P54763-4] NP_034272.1, NM_010142.4 [P54763-3] XP_006538594.1, XM_006538531.3 [P54763-2] |
Genome annotation databases
Ensembli | ENSMUST00000059287; ENSMUSP00000058135; ENSMUSG00000028664 [P54763-4] ENSMUST00000105845; ENSMUSP00000101471; ENSMUSG00000028664 [P54763-3] ENSMUST00000105846; ENSMUSP00000101472; ENSMUSG00000028664 [P54763-2] |
GeneIDi | 13844 |
KEGGi | mmu:13844 |
UCSCi | uc008vim.2, mouse uc008vin.2, mouse |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | JH584273 Genomic DNA No translation available. BC043088 mRNA Translation: AAH43088.2 BC062924 mRNA Translation: AAH62924.1 Different initiation. L25890 mRNA Translation: AAA72411.1 Different initiation. X76011 mRNA Translation: CAA53598.1 |
RefSeqi | NP_001277682.1, NM_001290753.2 [P54763-4] NP_034272.1, NM_010142.4 [P54763-3] XP_006538594.1, XM_006538531.3 [P54763-2] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1JPA | X-ray | 1.91 | A/B | 587-898 | [»] | |
1KGY | X-ray | 2.70 | A/B/C/D | 20-199 | [»] | |
1NUK | X-ray | 2.90 | A | 20-202 | [»] | |
1SHW | X-ray | 2.20 | B | 19-199 | [»] | |
2HEN | X-ray | 2.60 | A/B/C/D | 614-898 | [»] | |
3ETP | X-ray | 2.00 | A | 20-199 | [»] | |
BMRBi | P54763 | |||||
SMRi | P54763 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
CORUMi | P54763 |
DIPi | DIP-34917N |
IntActi | P54763, 14 interactors |
MINTi | P54763 |
STRINGi | 10090.ENSMUSP00000101472 |
Chemistry databases
BindingDBi | P54763 |
ChEMBLi | CHEMBL5961 |
GuidetoPHARMACOLOGYi | 1831 |
PTM databases
GlyGeni | P54763, 4 sites |
iPTMneti | P54763 |
PhosphoSitePlusi | P54763 |
SwissPalmi | P54763 |
Proteomic databases
jPOSTi | P54763 |
MaxQBi | P54763 |
PaxDbi | P54763 |
PRIDEi | P54763 |
Protocols and materials databases
Antibodypediai | 30106, 639 antibodies |
DNASUi | 13844 |
Genome annotation databases
Ensembli | ENSMUST00000059287; ENSMUSP00000058135; ENSMUSG00000028664 [P54763-4] ENSMUST00000105845; ENSMUSP00000101471; ENSMUSG00000028664 [P54763-3] ENSMUST00000105846; ENSMUSP00000101472; ENSMUSG00000028664 [P54763-2] |
GeneIDi | 13844 |
KEGGi | mmu:13844 |
UCSCi | uc008vim.2, mouse uc008vin.2, mouse |
Organism-specific databases
CTDi | 2048 |
MGIi | MGI:99611, Ephb2 |
Phylogenomic databases
eggNOGi | KOG0196, Eukaryota |
GeneTreei | ENSGT00940000155503 |
InParanoidi | P54763 |
OMAi | YYYESDF |
OrthoDBi | 933071at2759 |
TreeFami | TF315608 |
Enzyme and pathway databases
Reactomei | R-MMU-2682334, EPH-Ephrin signaling R-MMU-3928662, EPHB-mediated forward signaling R-MMU-3928664, Ephrin signaling R-MMU-3928665, EPH-ephrin mediated repulsion of cells |
Miscellaneous databases
BioGRID-ORCSi | 13844, 0 hits in 17 CRISPR screens |
ChiTaRSi | Ephb2, mouse |
EvolutionaryTracei | P54763 |
PROi | PR:P54763 |
RNActi | P54763, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000028664, Expressed in floor plate of midbrain and 320 other tissues |
ExpressionAtlasi | P54763, baseline and differential |
Family and domain databases
CDDi | cd10477, EphR_LBD_B2, 1 hit cd00063, FN3, 2 hits |
Gene3Di | 1.10.150.50, 1 hit 2.60.120.260, 1 hit 2.60.40.10, 2 hits |
InterProi | View protein in InterPro IPR027936, Eph_TM IPR034238, EphB2_rcpt_lig-bd IPR001090, Ephrin_rcpt_lig-bd_dom IPR003961, FN3_dom IPR036116, FN3_sf IPR008979, Galactose-bd-like_sf IPR009030, Growth_fac_rcpt_cys_sf IPR013783, Ig-like_fold IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR001660, SAM IPR013761, SAM/pointed_sf IPR001245, Ser-Thr/Tyr_kinase_cat_dom IPR011641, Tyr-kin_ephrin_A/B_rcpt-like IPR008266, Tyr_kinase_AS IPR020635, Tyr_kinase_cat_dom IPR016257, Tyr_kinase_ephrin_rcpt IPR001426, Tyr_kinase_rcpt_V_CS |
Pfami | View protein in Pfam PF14575, EphA2_TM, 1 hit PF01404, Ephrin_lbd, 1 hit PF07699, Ephrin_rec_like, 1 hit PF00041, fn3, 2 hits PF07714, PK_Tyr_Ser-Thr, 1 hit PF00536, SAM_1, 1 hit |
PIRSFi | PIRSF000666, TyrPK_ephrin_receptor, 1 hit |
PRINTSi | PR00109, TYRKINASE |
SMARTi | View protein in SMART SM00615, EPH_lbd, 1 hit SM01411, Ephrin_rec_like, 1 hit SM00060, FN3, 2 hits SM00454, SAM, 1 hit SM00219, TyrKc, 1 hit |
SUPFAMi | SSF47769, SSF47769, 1 hit SSF49265, SSF49265, 1 hit SSF49785, SSF49785, 1 hit SSF56112, SSF56112, 1 hit SSF57184, SSF57184, 1 hit |
PROSITEi | View protein in PROSITE PS51550, EPH_LBD, 1 hit PS50853, FN3, 2 hits PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00109, PROTEIN_KINASE_TYR, 1 hit PS00790, RECEPTOR_TYR_KIN_V_1, 1 hit PS00791, RECEPTOR_TYR_KIN_V_2, 1 hit PS50105, SAM_DOMAIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | EPHB2_MOUSE | |
Accessioni | P54763Primary (citable) accession number: P54763 Secondary accession number(s): A3KG00 Q9QVY4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1996 |
Last sequence update: | October 14, 2015 | |
Last modified: | December 2, 2020 | |
This is version 210 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Human and mouse protein kinases
Human and mouse protein kinases: classification and index