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UniProtKB - P54745 (MNGA_ECOLI)

Entry version 169 (02 Jun 2021)
Sequence version 1 (01 Oct 1996)
Previous versions | rss
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Protein

PTS system 2-O-alpha-mannosyl-D-glycerate-specific EIIABC component

Gene

mngA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (PubMed:14645248, PubMed:9063979).

This system is involved in mannosyl-D-glycerate transport (PubMed:14645248).

Also involved in thermoinduction of ompC (PubMed:9063979).

2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=10 µM for mannosyl-D-glycerate1 Publication
  1. Vmax=0.65 nmol/min/mg enzyme for mannosyl-D-glycerate1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei87Tele-phosphohistidine intermediate; for EIIA activityPROSITE-ProRule annotation1 Publication1
Active sitei192Phosphocysteine intermediate; for EIIB activity1 Publication1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Transferase
Biological processPhosphotransferase system, Sugar transport, Transport

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		EcoCyc:HRSA-MONOMER
MetaCyc:HRSA-MONOMER

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		2.7.1.195, 2026

Protein family/group databases

Transport Classification Database

More...TCDBi		4.A.2.1.3, the pts fructose-mannitol (fru) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
PTS system 2-O-alpha-mannosyl-D-glycerate-specific EIIABC component1 Publication
Alternative name(s):
2-O-alpha-mannosyl-D-glycerate-specific phosphotransferase enzyme MngA1 Publication
Protein-Npi-phosphohistidine--2-O-alpha-mannosyl-D-glycerate phosphotransferase1 Publication
Including the following 3 domains:
2-O-alpha-mannosyl-D-glycerate-specific phosphotransferase enzyme IIA component1 Publication
Alternative name(s):
PTS system EIIA component1 Publication
2-O-alpha-mannosyl-D-glycerate-specific phosphotransferase enzyme IIB component1 Publication (EC:2.7.1.1951 Publication)
Alternative name(s):
PTS system EIIB component1 Publication
2-O-alpha-mannosyl-D-glycerate-specific permease IIC component1 Publication
Alternative name(s):
PTS system EIIC component1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mngA1 Publication
Synonyms:hrsA1 Publication
Ordered Locus Names:b0731, JW0720
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 313PeriplasmicSequence analysisAdd BLAST313
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei314 – 334HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini335 – 358CytoplasmicSequence analysisAdd BLAST24
Transmembranei359 – 379HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini380 – 389PeriplasmicSequence analysis10
Transmembranei390 – 410HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini411 – 433CytoplasmicSequence analysisAdd BLAST23
Transmembranei434 – 454HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini455 – 474PeriplasmicSequence analysisAdd BLAST20
Transmembranei475 – 495HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini496 – 500CytoplasmicSequence analysis5
Transmembranei501 – 521HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini522 – 551PeriplasmicSequence analysisAdd BLAST30
Transmembranei552 – 572HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini573CytoplasmicSequence analysis1
Transmembranei574 – 594HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini595 – 620PeriplasmicSequence analysisAdd BLAST26
Transmembranei621 – 641HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini642 – 658CytoplasmicSequence analysisAdd BLAST17

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Cells lacking this gene are unable to transport mannosyl-D-glycerate.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001866991 – 658PTS system 2-O-alpha-mannosyl-D-glycerate-specific EIIABC componentAdd BLAST658

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei87Phosphohistidine; by HPrCurated1
Modified residuei192Phosphocysteine; by EIIAPROSITE-ProRule annotationCurated1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P54745

PRoteomics IDEntifications database

More...PRIDEi		P54745

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Induced by mannosyl-D-glycerate. Repressed by MngR.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		4263541, 15 interactors
849731, 1 interactor

Database of interacting proteins

More...DIPi		DIP-9939N

Protein interaction database and analysis system

More...IntActi		P54745, 1 interactor

STRING: functional protein association networks

More...STRINGi		511145.b0731

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P54745

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini25 – 171PTS EIIA type-2PROSITE-ProRule annotationAdd BLAST147
Domaini186 – 282PTS EIIB type-2PROSITE-ProRule annotationAdd BLAST97
Domaini306 – 641PTS EIIC type-2PROSITE-ProRule annotationAdd BLAST336

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The PTS EIIA type-2 domain is phosphorylated by phospho-HPr on a histidyl residue. Then, it transfers the phosphoryl group to the PTS EIIB type-2 domain.PROSITE-ProRule annotation
The PTS EIIB type-2 domain is phosphorylated by phospho-EIIA on a cysteinyl residue. Then, it transfers the phosphoryl group to the sugar substrate concomitantly with the sugar uptake processed by the PTS EIIC type-2 domain.PROSITE-ProRule annotation
The EIIC type-2 domain forms the PTS system translocation channel and contains the specific substrate-binding site.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG1299, Bacteria
COG1445, Bacteria
COG1762, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_013155_1_2_6

Database for complete collections of gene phylogenies

More...PhylomeDBi		P54745

Family and domain databases

Conserved Domains Database

More...CDDi		cd00211, PTS_IIA_fru, 1 hit
cd05569, PTS_IIB_fructose, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.930.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR016152, PTrfase/Anion_transptr
IPR002178, PTS_EIIA_type-2_dom
IPR036095, PTS_EIIB-like_sf
IPR013011, PTS_EIIB_2
IPR003501, PTS_EIIB_2/3
IPR003352, PTS_EIIC
IPR013014, PTS_EIIC_2
IPR004715, PTS_IIA_fruc
IPR003353, PTS_IIB_fruc
IPR006327, PTS_IIC_fruc

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00359, PTS_EIIA_2, 1 hit
PF02378, PTS_EIIC, 1 hit
PF02302, PTS_IIB, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52794, SSF52794, 1 hit
SSF55804, SSF55804, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00829, FRU, 1 hit
TIGR00848, fruA, 1 hit
TIGR01427, PTS_IIC_fructo, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51094, PTS_EIIA_TYPE_2, 1 hit
PS00372, PTS_EIIA_TYPE_2_HIS, 1 hit
PS51099, PTS_EIIB_TYPE_2, 1 hit
PS51104, PTS_EIIC_TYPE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P54745-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVLFYRAHWR DYKNDQVRIM MNLTTLTHRD ALCLNARFTS REEAIHALTQ 
        60         70         80         90        100
RLAALGKISS TEQFLEEVYR RESLGPTALG EGLAVPHGKT AAVKEAAFAV 
       110        120        130        140        150
ATLSEPLQWE GVDGPEAVDL VVLLAIPPNE AGTTHMQLLT ALTTRLADDE 
       160        170        180        190        200
IRARIQSATT PDELLSALDD KGGTQPSASF SNAPTIVCVT ACPAGIAHTY 
       210        220        230        240        250
MAAEYLEKAG RKLGVNVYVE KQGANGIEGR LTADQLNSAT ACIFAAEVAI 
       260        270        280        290        300
KESERFNGIP ALSVPVAEPI RHAEALIQQA LTLKRSDETR TVQQDTQPVK 
       310        320        330        340        350
SVKTELKQAL LSGISFAVPL IVAGGTVLAV AVLLSQIFGL QDLFNEENSW 
       360        370        380        390        400
LWMYRKLGGG LLGILMVPVL AAYTAYSLAD KPALAPGFAA GLAANMIGSG 
       410        420        430        440        450
FLGAVVGGLI AGYLMRWVKN HLRLSSKFNG FLTFYLYPVL GTLGAGSLML 
       460        470        480        490        500
FVVGEPVAWI NNSLTAWLNG LSGSNALLLG AILGFMCSFD LGGPVNKAAY 
       510        520        530        540        550
AFCLGAMANG VYGPYAIFAS VKMVSAFTVT ASTMLAPRLF KEFEIETGKS 
       560        570        580        590        600
TWLLGLAGIT EGAIPMAIED PLRVIGSFVL GSMVTGAIVG AMNIGLSTPG 
       610        620        630        640        650
AGIFSLFLLH DNGAGGVMAA IGWFGAALVG AAISTAILLM WRRHAVKHGN 

YLTDGVMP
Length:658
Mass (Da):69,668
Last modified:October 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC1F0999A1C48C5C2
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
D64014 Genomic DNA Translation: BAA10893.1
U00096 Genomic DNA Translation: AAC73825.1
AP009048 Genomic DNA Translation: BAA35397.2

Protein sequence database of the Protein Information Resource

More...PIRi		JC4598

NCBI Reference Sequences

More...RefSeqi		NP_415259.1, NC_000913.3
WP_000242633.1, NZ_CP047127.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAC73825; AAC73825; b0731
BAA35397; BAA35397; BAA35397

Database of genes from NCBI RefSeq genomes

More...GeneIDi		945355

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ecj:JW0720
eco:b0731

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|511145.12.peg.761

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D64014 Genomic DNA Translation: BAA10893.1
U00096 Genomic DNA Translation: AAC73825.1
AP009048 Genomic DNA Translation: BAA35397.2
PIRiJC4598
RefSeqiNP_415259.1, NC_000913.3
WP_000242633.1, NZ_CP047127.1

3D structure databases

SMRiP54745
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi4263541, 15 interactors
849731, 1 interactor
DIPiDIP-9939N
IntActiP54745, 1 interactor
STRINGi511145.b0731

Protein family/group databases

TCDBi4.A.2.1.3, the pts fructose-mannitol (fru) family

Proteomic databases

PaxDbiP54745
PRIDEiP54745

Genome annotation databases

EnsemblBacteriaiAAC73825; AAC73825; b0731
BAA35397; BAA35397; BAA35397
GeneIDi945355
KEGGiecj:JW0720
eco:b0731
PATRICifig|511145.12.peg.761

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...EchoBASEi		EB3024

Phylogenomic databases

eggNOGiCOG1299, Bacteria
COG1445, Bacteria
COG1762, Bacteria
HOGENOMiCLU_013155_1_2_6
PhylomeDBiP54745

Enzyme and pathway databases

BioCyciEcoCyc:HRSA-MONOMER
MetaCyc:HRSA-MONOMER
BRENDAi2.7.1.195, 2026

Miscellaneous databases

Protein Ontology

More...PROi		PR:P54745

Family and domain databases

CDDicd00211, PTS_IIA_fru, 1 hit
cd05569, PTS_IIB_fructose, 1 hit
Gene3Di3.40.930.10, 1 hit
InterProiView protein in InterPro
IPR016152, PTrfase/Anion_transptr
IPR002178, PTS_EIIA_type-2_dom
IPR036095, PTS_EIIB-like_sf
IPR013011, PTS_EIIB_2
IPR003501, PTS_EIIB_2/3
IPR003352, PTS_EIIC
IPR013014, PTS_EIIC_2
IPR004715, PTS_IIA_fruc
IPR003353, PTS_IIB_fruc
IPR006327, PTS_IIC_fruc
PfamiView protein in Pfam
PF00359, PTS_EIIA_2, 1 hit
PF02378, PTS_EIIC, 1 hit
PF02302, PTS_IIB, 1 hit
SUPFAMiSSF52794, SSF52794, 1 hit
SSF55804, SSF55804, 1 hit
TIGRFAMsiTIGR00829, FRU, 1 hit
TIGR00848, fruA, 1 hit
TIGR01427, PTS_IIC_fructo, 1 hit
PROSITEiView protein in PROSITE
PS51094, PTS_EIIA_TYPE_2, 1 hit
PS00372, PTS_EIIA_TYPE_2_HIS, 1 hit
PS51099, PTS_EIIB_TYPE_2, 1 hit
PS51104, PTS_EIIC_TYPE_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMNGA_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P54745
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: June 2, 2021
This is version 169 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome
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