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Entry version 134 (26 Feb 2020)
Sequence version 2 (04 Dec 2007)
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Protein

Phosphatidylinositol 3-kinase 3

Gene

pikC

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.7.1.137 1939

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DDI-114604 GPVI-mediated activation cascade
R-DDI-1660499 Synthesis of PIPs at the plasma membrane
R-DDI-1660514 Synthesis of PIPs at the Golgi membrane
R-DDI-1660516 Synthesis of PIPs at the early endosome membrane
R-DDI-1660517 Synthesis of PIPs at the late endosome membrane
R-DDI-392451 G beta:gamma signalling through PI3Kgamma
R-DDI-432722 Golgi Associated Vesicle Biogenesis
R-DDI-8856828 Clathrin-mediated endocytosis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Phosphatidylinositol 3-kinase 3 (EC:2.7.1.137)
Short name:
PI3-kinase
Short name:
PI3K
Short name:
PtdIns-3-kinase
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:pikC
Synonyms:pik3
ORF Names:DDB_G0275011
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDictyostelium discoideum (Slime mold)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44689 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaEvoseaEumycetozoaDictyosteliaDictyostelialesDictyosteliaceaeDictyostelium
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002195 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 2, Unassembled WGS sequence

Organism-specific databases

Dictyostelium discoideum online informatics resource

More...
dictyBasei
DDB_G0275011 pikC

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000888241 – 1697Phosphatidylinositol 3-kinase 3Add BLAST1697

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P54675

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
44689.DDB0185203

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P54675

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini737 – 823PI3K-RBDPROSITE-ProRule annotationAdd BLAST87
Domaini888 – 1036C2 PI3K-typePROSITE-ProRule annotationAdd BLAST149
Domaini1060 – 1238PIK helicalPROSITE-ProRule annotationAdd BLAST179
Domaini1333 – 1596PI3K/PI4KPROSITE-ProRule annotationAdd BLAST264
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1622 – 162615
Repeati1627 – 163125
Repeati1632 – 163635
Repeati1642 – 164645
Repeati1647 – 165155

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1622 – 16515 X 5 AA approximate repeatsAdd BLAST30
Regioni1659 – 16727 X 2 AA tandem repeats of K-EAdd BLAST14

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi170 – 196Poly-AsnAdd BLAST27
Compositional biasi210 – 222Poly-AsnAdd BLAST13
Compositional biasi312 – 338Poly-AsnAdd BLAST27
Compositional biasi351 – 366Poly-AsnAdd BLAST16
Compositional biasi457 – 490Poly-AsnAdd BLAST34
Compositional biasi495 – 502Poly-Asn8
Compositional biasi596 – 600Poly-Ser5
Compositional biasi832 – 849Poly-GlnAdd BLAST18
Compositional biasi1681 – 1687Poly-Asn7

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PI3/PI4-kinase family.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0905 Eukaryota
COG5032 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_240995_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P54675

KEGG Orthology (KO)

More...
KOi
K00922

Identification of Orthologs from Complete Genome Data

More...
OMAi
LIHESIG

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P54675

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00891 PI3Kc, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1070.11, 1 hit
1.25.40.70, 1 hit
2.60.40.150, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR035892 C2_domain_sf
IPR011009 Kinase-like_dom_sf
IPR000403 PI3/4_kinase_cat_dom
IPR036940 PI3/4_kinase_cat_sf
IPR018936 PI3/4_kinase_CS
IPR001263 PI3K_accessory_dom
IPR042236 PI3K_accessory_sf
IPR002420 PI3K_C2_dom
IPR000341 PI3K_Ras-bd_dom
IPR035448 PI3Kc
IPR015433 PI_Kinase
IPR029071 Ubiquitin-like_domsf

The PANTHER Classification System

More...
PANTHERi
PTHR10048 PTHR10048, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00454 PI3_PI4_kinase, 1 hit
PF00792 PI3K_C2, 1 hit
PF00794 PI3K_rbd, 1 hit
PF00613 PI3Ka, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00142 PI3K_C2, 1 hit
SM00144 PI3K_rbd, 1 hit
SM00145 PI3Ka, 1 hit
SM00146 PI3Kc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit
SSF54236 SSF54236, 1 hit
SSF56112 SSF56112, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00915 PI3_4_KINASE_1, 1 hit
PS00916 PI3_4_KINASE_2, 1 hit
PS50290 PI3_4_KINASE_3, 1 hit
PS51547 PI3K_C2, 1 hit
PS51546 PI3K_RBD, 1 hit
PS51545 PIK_HELICAL, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P54675-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRQIVTGVIH QTTQSQQIPN VINSNQIQFS NEPMVVGSIE DFDIDSEVPP
60 70 80 90 100
LAINLQRSIN NNNNNNNNNN NNNNNNNNNN NNNNNNNTQP CTTVFLDRDS
110 120 130 140 150
CVNVKATIDL LKEQLEFTIK DLIDFKENYD KLESTEQFKQ WSNLIKNIKE
160 170 180 190 200
NSLNNSNIYL TIPTTQNLIN NNNNNNNNNN NNNNNNNNNN NNNNNNVIIP
210 220 230 240 250
SASTENKEEN DNNNSNNNNN INLSPDSSIT KDINITENKI TEIKTTETKE
260 270 280 290 300
TSTGTSPLEK SPSKGFIISP KKPEEENEIE GETINNIAIT NYTQGPSMLT
310 320 330 340 350
LMKKKLENIK KNNNNNNNNG NGNNNSNNNN SNSNNNNNGI SPSSSPPSHL
360 370 380 390 400
NGNNNNNNSN NTNSNNTTNA TTNSVGFSIT MTNSNSLSVS KRMNKFKSWT
410 420 430 440 450
SSKPTSSSIG FASSPQNNGK PLNISGSSRF FTSRQDSKID LLKSPSSSPP
460 470 480 490 500
TQSDIFNENN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN EELINNNNNN
510 520 530 540 550
NNDENYKIEE TEESLKELLE KEKLENEERE KILKERNEID NLKKKNHLSK
560 570 580 590 600
GYFMRACNAS NDDGLEEEDI PLQDEHWETN VIVLLPCRHH VKVPGSSSSS
610 620 630 640 650
IDSIRQLAWA SGKMQGHLNL EKDEKFFTLR WCNKDVVFDQ DTPLGHLIQY
660 670 680 690 700
NLNYNNPTQK PTNIKLELVL EDELCKERLV DLQSLEINNG RPSIWKSHID
710 720 730 740 750
DVLSFNRKLR ELAMLAKPQS NVPAARLTPY PPPKTIPEFF VIRVHLFKNQ
760 770 780 790 800
TKSLRCANNH TAFSLMTILS EKLKNTTPFD PTQYRFLITG INQYVDPNVP
810 820 830 840 850
LLSVEYIVEK IKRKGEIDLT MVELLSLGLI IQQQQQQQQQ QQQQQQQQQI
860 870 880 890 900
ENIDDENILK LNNGILNVLS KIEKPIREKD NCISSLTVTE NLQVRLLHAH
910 920 930 940 950
EIFASKASEI IGTDSPSIQL FIEAAVYFGG ELLATQSSKL VSFQDTVVWN
960 970 980 990 1000
EWVNIPLAVS NIPNGARMCL GLNARYRGDI FNIGWVGHRL FDSKGILNTF
1010 1020 1030 1040 1050
APFSLLLWPG KINPIGTCVD NLESKDQAII IAFEFKDYVV PKTIHYEDDL
1060 1070 1080 1090 1100
IELISKDENG NELPVVTMEE MDRVEQIILQ DPLYSLNKEE RLLIWKSRYF
1110 1120 1130 1140 1150
CHTKPQALSK LLQSVEWTNY KQVGEAFQLL KIWPTLSAVD ALELLDPKFA
1160 1170 1180 1190 1200
DCVEIREYAV KCLDQMSDYE LEIYMLQLVQ AIKHDVFHNS VLSLFLIGRV
1210 1220 1230 1240 1250
WQNMQVLGHP FFWHLRADID NQEVCERFRV LSSGFLRYAP TQLMESFKRE
1260 1270 1280 1290 1300
ITTLRILENL AKRVKEVPYE KRKQYVENNL REEQSFPTEL FVPFDPSIRI
1310 1320 1330 1340 1350
LNIIPEKCKS MDSAKVPLWV TFKNADPFAP PLQMIAKTGD DLRQDILTLQ
1360 1370 1380 1390 1400
LLRLMDHMWK SQDLDLHMTI YRCIATGMGT GLIEVVPNSE TAARIQAGAG
1410 1420 1430 1440 1450
GVSGAFKQTP IANWLKNHNQ TENSYQKAVS KFTLSCAGYC VATYVLGIGD
1460 1470 1480 1490 1500
RHNDNIMVDI HGHLFHIDFG HFLGNFKTFA GFQREKAPFV LTPDFVYVIG
1510 1520 1530 1540 1550
GKDSPNFAFF VDICCKAFNI IRSNAHVFIN MFELMLSTGI PELRSENDIV
1560 1570 1580 1590 1600
YLRDKFRLDL TDAEASEYFK KLIHESIGTL TTTINFAIHI MAHRKNLVSG
1610 1620 1630 1640 1650
NSAPKIGSAS SLNLNKNKPS SQSKLDLSRS DLSRSDSSRS DSSRLDLSRS
1660 1670 1680 1690
DKKNNKDNKE KEKEKEKEKE KENNDNNDKD NNNNSNNDTE KENSIDK
Length:1,697
Mass (Da):192,942
Last modified:December 4, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC5442DC2C3202E32
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1159A → T in AAA85723 (PubMed:7565716).Curated1
Sequence conflicti1175M → L in AAA85723 (PubMed:7565716).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAFI02000013 Genomic DNA Translation: EAL69786.1
U23478 mRNA Translation: AAA85723.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T18274

NCBI Reference Sequences

More...
RefSeqi
XP_643820.1, XM_638728.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EAL69786; EAL69786; DDB_G0275011

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8619867

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ddi:DDB_G0275011

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000013 Genomic DNA Translation: EAL69786.1
U23478 mRNA Translation: AAA85723.1
PIRiT18274
RefSeqiXP_643820.1, XM_638728.1

3D structure databases

SMRiP54675
ModBaseiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0185203

Proteomic databases

PaxDbiP54675

Genome annotation databases

EnsemblProtistsiEAL69786; EAL69786; DDB_G0275011
GeneIDi8619867
KEGGiddi:DDB_G0275011

Organism-specific databases

dictyBaseiDDB_G0275011 pikC

Phylogenomic databases

eggNOGiKOG0905 Eukaryota
COG5032 LUCA
HOGENOMiCLU_240995_0_0_1
InParanoidiP54675
KOiK00922
OMAiLIHESIG
PhylomeDBiP54675

Enzyme and pathway databases

BRENDAi2.7.1.137 1939
ReactomeiR-DDI-114604 GPVI-mediated activation cascade
R-DDI-1660499 Synthesis of PIPs at the plasma membrane
R-DDI-1660514 Synthesis of PIPs at the Golgi membrane
R-DDI-1660516 Synthesis of PIPs at the early endosome membrane
R-DDI-1660517 Synthesis of PIPs at the late endosome membrane
R-DDI-392451 G beta:gamma signalling through PI3Kgamma
R-DDI-432722 Golgi Associated Vesicle Biogenesis
R-DDI-8856828 Clathrin-mediated endocytosis

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P54675

Family and domain databases

CDDicd00891 PI3Kc, 1 hit
Gene3Di1.10.1070.11, 1 hit
1.25.40.70, 1 hit
2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR035892 C2_domain_sf
IPR011009 Kinase-like_dom_sf
IPR000403 PI3/4_kinase_cat_dom
IPR036940 PI3/4_kinase_cat_sf
IPR018936 PI3/4_kinase_CS
IPR001263 PI3K_accessory_dom
IPR042236 PI3K_accessory_sf
IPR002420 PI3K_C2_dom
IPR000341 PI3K_Ras-bd_dom
IPR035448 PI3Kc
IPR015433 PI_Kinase
IPR029071 Ubiquitin-like_domsf
PANTHERiPTHR10048 PTHR10048, 1 hit
PfamiView protein in Pfam
PF00454 PI3_PI4_kinase, 1 hit
PF00792 PI3K_C2, 1 hit
PF00794 PI3K_rbd, 1 hit
PF00613 PI3Ka, 1 hit
SMARTiView protein in SMART
SM00142 PI3K_C2, 1 hit
SM00144 PI3K_rbd, 1 hit
SM00145 PI3Ka, 1 hit
SM00146 PI3Kc, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF54236 SSF54236, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00915 PI3_4_KINASE_1, 1 hit
PS00916 PI3_4_KINASE_2, 1 hit
PS50290 PI3_4_KINASE_3, 1 hit
PS51547 PI3K_C2, 1 hit
PS51546 PI3K_RBD, 1 hit
PS51545 PIK_HELICAL, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPI3K3_DICDI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P54675
Secondary accession number(s): Q553Z1, Q869X9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: December 4, 2007
Last modified: February 26, 2020
This is version 134 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
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