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Protein

14-3-3-like protein

Gene

fttB

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • myosin II heavy chain binding Source: dictyBase
  • protein domain specific binding Source: InterPro

GO - Biological processi

  • cleavage furrow ingression Source: dictyBase
  • cortical cytoskeleton organization Source: dictyBase
  • microtubule cytoskeleton organization Source: dictyBase
  • positive regulation of cytokinesis Source: dictyBase
  • protein localization Source: dictyBase
  • response to bacterium Source: dictyBase

Enzyme and pathway databases

ReactomeiR-DDI-1445148 Translocation of GLUT4 to the plasma membrane
R-DDI-3371453 Regulation of HSF1-mediated heat shock response
R-DDI-3371511 HSF1 activation
R-DDI-5625740 RHO GTPases activate PKNs
R-DDI-5628897 TP53 Regulates Metabolic Genes
R-DDI-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
R-DDI-8876198 RAB GEFs exchange GTP for GDP on RABs

Names & Taxonomyi

Protein namesi
Recommended name:
14-3-3-like protein
Gene namesi
Name:fttB
ORF Names:DDB_G0269138
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 1, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0269138 fttB

Subcellular locationi

GO - Cellular componenti

  • cell cortex Source: dictyBase
  • centrosome Source: dictyBase
  • nucleus Source: dictyBase
  • phagocytic vesicle Source: dictyBase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000586491 – 25214-3-3-like proteinAdd BLAST252

Proteomic databases

PaxDbiP54632
PRIDEiP54632

Interactioni

GO - Molecular functioni

  • myosin II heavy chain binding Source: dictyBase
  • protein domain specific binding Source: InterPro

Protein-protein interaction databases

STRINGi44689.DDB0232938

Structurei

3D structure databases

ProteinModelPortaliP54632
SMRiP54632
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 14-3-3 family.Curated

Phylogenomic databases

eggNOGiKOG0841 Eukaryota
COG5040 LUCA
InParanoidiP54632
KOiK06630
OMAiIPCATTG
PhylomeDBiP54632

Family and domain databases

Gene3Di1.20.190.20, 1 hit
InterProiView protein in InterPro
IPR000308 14-3-3
IPR023409 14-3-3_CS
IPR036815 14-3-3_dom_sf
IPR023410 14-3-3_domain
PANTHERiPTHR18860 PTHR18860, 1 hit
PfamiView protein in Pfam
PF00244 14-3-3, 1 hit
PIRSFiPIRSF000868 14-3-3, 1 hit
PRINTSiPR00305 1433ZETA
SMARTiView protein in SMART
SM00101 14_3_3, 1 hit
SUPFAMiSSF48445 SSF48445, 1 hit
PROSITEiView protein in PROSITE
PS00796 1433_1, 1 hit
PS00797 1433_2, 1 hit

Sequencei

Sequence statusi: Complete.

P54632-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTREENVYMA KLAEQAERYE EMVEAMKKVA ELDVELTVEE RNLLSVAYKN
60 70 80 90 100
VIGARRASWR IISSIEQKEE SKGNENHVKK IKEYKCKVEK ELTDICNDIL
110 120 130 140 150
EVLESHLIVS SASGESKVFY YKMKGDYFRY LAEFATGNPR KTSAESSLIA
160 170 180 190 200
YKAASDIAVT ELPPTHPIRL GLALNFSVFY YEILNSPDRA CNLAKTAFDD
210 220 230 240 250
AIAELDTLSE DSYKDSTLIM QLLRDNLTLW TSDVHNMEKN QDGDDDQNEP

GM
Length:252
Mass (Da):28,704
Last modified:December 4, 2007 - v2
Checksum:i30F03CC39D4E273D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti25A → T in CAA64814 (PubMed:9223628).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X95568 mRNA Translation: CAA64814.1
AAFI02000005 Genomic DNA Translation: EAS66939.1
RefSeqiXP_001134475.1, XM_001134475.1

Genome annotation databases

EnsemblProtistsiEAS66939; EAS66939; DDB_G0269138
GeneIDi8617398
KEGGiddi:DDB_G0269138

Similar proteinsi

Entry informationi

Entry namei1433_DICDI
AccessioniPrimary (citable) accession number: P54632
Secondary accession number(s): Q1ZXP9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: December 4, 2007
Last modified: February 28, 2018
This is version 100 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

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