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UniProtKB - P54352 (EAS_DROME)

Entry version 168 (23 Feb 2022)
Sequence version 2 (24 Mar 2009)
Previous versions | rss
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Protein

Ethanolamine kinase

Gene

eas

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Highly specific for ethanolamine phosphorylation. May be a rate-controlling step in phosphatidylethanolamine biosynthesis.

1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: phosphatidylethanolamine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes phosphatidylethanolamine from ethanolamine.1 Publication This subpathway is part of the pathway phosphatidylethanolamine biosynthesis, which is itself part of Phospholipid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes phosphatidylethanolamine from ethanolamine, the pathway phosphatidylethanolamine biosynthesis and in Phospholipid metabolism.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • choline kinase activity Source: FlyBase
  • ethanolamine kinase activity Source: FlyBase
Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Transferase
Biological processLipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-DME-1483213, Synthesis of PE

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi		UPA00558;UER00741

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ethanolamine kinase (EC:2.7.1.821 Publication)
Short name:
EK
Alternative name(s):
Protein easily shocked
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:eas
ORF Names:CG3525
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Drosophila genome database

More...FlyBasei		FBgn0000536, eas

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		VectorBase:FBgn0000536

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

'Bang sensitive' phenotype; induction of paralysis with electrical stimulation results in a brief seizure, followed by a failure of the muscles to respond to giant fiber stimulation. This is due to an excitability defect caused by altered membrane phospholipid composition.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002062311 – 518Ethanolamine kinaseAdd BLAST518

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei190Phosphoserine2 Publications1
Modified residuei194Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P54352

PRoteomics IDEntifications database

More...PRIDEi		P54352

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P54352

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P54352, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		58926, 23 interactors

Protein interaction database and analysis system

More...IntActi		P54352, 2 interactors

STRING: functional protein association networks

More...STRINGi		7227.FBpp0073990

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P54352

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 88DisorderedSequence analysisAdd BLAST88

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 71Polar residuesSequence analysisAdd BLAST71
Compositional biasi72 – 88Basic and acidic residuesSequence analysisAdd BLAST17

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the choline/ethanolamine kinase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4720, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00950000182939

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P54352

Identification of Orthologs from Complete Genome Data

More...OMAi		WTVLQKW

Database for complete collections of gene phylogenies

More...PhylomeDBi		P54352

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011009, Kinase-like_dom_sf

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF56112, SSF56112, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform E (identifier: P54352-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGTETKSNSY TGQISTSGGN PKVMKDSLSL VRQTVNQQTL SLSQSNQVQN 
        60         70         80         90        100
QLNSHSNSNS YPNPSGSENK NENEQNSRDI RAKPEDKSRK EAIVPFVPIF 
       110        120        130        140        150
VEEADVIQGA KELLKVIRPT WDLSHVEFKI RVVPQIEDRY PAQNAMVMMT 
       160        170        180        190        200
LYSFTDGITN KLVGCFHKEI SKLNDENGGS YLPIKTQGLS PVQSEDPVII 
       210        220        230        240        250
EKEDDDEFTD DRAADDGSPV QYSDNVVLVR IYGNKTDLLI DRKAETQNFL 
       260        270        280        290        300
LLHTYGLAPS LYATFKNGLV YEYVPGTTLN TDSVLCPEIW PLVARRMAEM 
       310        320        330        340        350
HRKVRKHGDS SATKPMPMIW KKTQSFLDLV PERFSDAEKH KRVKETFLPI 
       360        370        380        390        400
GRLREEFNKL YEYLEALDSP IVFSHNDLLL GNVIYTQSLN TVNFIDYEYA 
       410        420        430        440        450
DYNFQAFDIG NHFAEMCGVD EVDYSRYPKR EFQLQWLRVY LEEYLQRSNI 
       460        470        480        490        500
QNDEVELLYV QVNQFALASH IFWTVWSLLQ AEHSTIDFDY VGYAFLRYNE 
       510 
YLARKVEFLS LTAAKNNK
Length:518
Mass (Da):59,563
Last modified:March 24, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i90768FF07A119436
GO
Isoform A (identifier: P54352-2) [UniParc]FASTAAdd to basket
Also known as: B, C, H, I

The sequence of this isoform differs from the canonical sequence as follows:
     130-152: Missing.

Show »
Length:495
Mass (Da):56,842
Checksum:iE706D95483387255
GO
Isoform G (identifier: P54352-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     2-30: GTETKSNSYTGQISTSGGNPKVMKDSLSL → STIRSKKN
     152-171: YSFTDGITNKLVGCFHKEIS → VLPMASQTNWSDVFIRRSPN
     172-518: Missing.

Show »
Length:150
Mass (Da):17,163
Checksum:i2C33B9FC6B0C1334
GO
Isoform F (identifier: P54352-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     152-171: YSFTDGITNKLVGCFHKEIS → VLPMASQTNWSDVFIRRSPN
     172-518: Missing.

Show »
Length:171
Mass (Da):19,219
Checksum:iEF6BFF7F2686140E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
X2JFQ7X2JFQ7_DROME
Easily shocked, isoform J
eas ala, Dmel\CG3525, EP770, EtnK, PC80
171Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence ABE73230 differs from that shown. Intron retention.Curated
The sequence ABE73230 differs from that shown. Reason: Frameshift.Curated
The sequence ACV91649 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti140 – 152YPAQN…MMTLY → VSGPKCDGDDDA in AAC37209 (PubMed:7923374).CuratedAdd BLAST13

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0539462 – 30GTETK…DSLSL → STIRSKKN in isoform G. CuratedAdd BLAST29
Alternative sequenceiVSP_001068130 – 152Missing in isoform A. 2 PublicationsAdd BLAST23
Alternative sequenceiVSP_053947152 – 171YSFTD…HKEIS → VLPMASQTNWSDVFIRRSPN in isoform F and isoform G. CuratedAdd BLAST20
Alternative sequenceiVSP_053948172 – 518Missing in isoform F and isoform G. CuratedAdd BLAST347

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
L35603 mRNA Translation: AAC37209.1
L35604 mRNA Translation: AAC37210.1
AE014298 Genomic DNA Translation: AAF48574.1
AE014298 Genomic DNA Translation: AAF48575.2
AE014298 Genomic DNA Translation: AAN09387.1
AE014298 Genomic DNA Translation: AAO41661.2
AE014298 Genomic DNA Translation: AFH07419.1
AE014298 Genomic DNA Translation: AFH07420.1
AY118437 mRNA Translation: AAM48466.1
BT025059 mRNA Translation: ABE73230.1 Sequence problems.
BT099812 mRNA Translation: ACV91649.1 Frameshift.

Protein sequence database of the Protein Information Resource

More...PIRi		A54980

NCBI Reference Sequences

More...RefSeqi		NP_001245706.1, NM_001258777.1 [P54352-5]
NP_001245707.1, NM_001258778.2 [P54352-4]
NP_001285319.1, NM_001298390.1 [P54352-5]
NP_523364.2, NM_078640.4 [P54352-2]
NP_727941.2, NM_167489.2 [P54352-2]
NP_727942.1, NM_167490.3 [P54352-2]
NP_727943.1, NM_167491.2 [P54352-2]
NP_788914.2, NM_176741.3 [P54352-2]

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		FBtr0074211; FBpp0073990; FBgn0000536 [P54352-2]
FBtr0074212; FBpp0073991; FBgn0000536 [P54352-2]
FBtr0074214; FBpp0073993; FBgn0000536 [P54352-2]
FBtr0308617; FBpp0300841; FBgn0000536 [P54352-5]
FBtr0308618; FBpp0300842; FBgn0000536 [P54352-4]
FBtr0308619; FBpp0300843; FBgn0000536 [P54352-2]
FBtr0343519; FBpp0310123; FBgn0000536 [P54352-2]
FBtr0343520; FBpp0310124; FBgn0000536 [P54352-5]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		32585

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		dme:Dmel_CG3525

UCSC genome browser

More...UCSCi		CG3525-RB, d. melanogaster
CG3525-RD, d. melanogaster
CG3525-RE, d. melanogaster

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L35603 mRNA Translation: AAC37209.1
L35604 mRNA Translation: AAC37210.1
AE014298 Genomic DNA Translation: AAF48574.1
AE014298 Genomic DNA Translation: AAF48575.2
AE014298 Genomic DNA Translation: AAN09387.1
AE014298 Genomic DNA Translation: AAO41661.2
AE014298 Genomic DNA Translation: AFH07419.1
AE014298 Genomic DNA Translation: AFH07420.1
AY118437 mRNA Translation: AAM48466.1
BT025059 mRNA Translation: ABE73230.1 Sequence problems.
BT099812 mRNA Translation: ACV91649.1 Frameshift.
PIRiA54980
RefSeqiNP_001245706.1, NM_001258777.1 [P54352-5]
NP_001245707.1, NM_001258778.2 [P54352-4]
NP_001285319.1, NM_001298390.1 [P54352-5]
NP_523364.2, NM_078640.4 [P54352-2]
NP_727941.2, NM_167489.2 [P54352-2]
NP_727942.1, NM_167490.3 [P54352-2]
NP_727943.1, NM_167491.2 [P54352-2]
NP_788914.2, NM_176741.3 [P54352-2]

3D structure databases

SMRiP54352
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi58926, 23 interactors
IntActiP54352, 2 interactors
STRINGi7227.FBpp0073990

PTM databases

iPTMnetiP54352

Proteomic databases

PaxDbiP54352
PRIDEiP54352

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		32585

Genome annotation databases

EnsemblMetazoaiFBtr0074211; FBpp0073990; FBgn0000536 [P54352-2]
FBtr0074212; FBpp0073991; FBgn0000536 [P54352-2]
FBtr0074214; FBpp0073993; FBgn0000536 [P54352-2]
FBtr0308617; FBpp0300841; FBgn0000536 [P54352-5]
FBtr0308618; FBpp0300842; FBgn0000536 [P54352-4]
FBtr0308619; FBpp0300843; FBgn0000536 [P54352-2]
FBtr0343519; FBpp0310123; FBgn0000536 [P54352-2]
FBtr0343520; FBpp0310124; FBgn0000536 [P54352-5]
GeneIDi32585
KEGGidme:Dmel_CG3525
UCSCiCG3525-RB, d. melanogaster
CG3525-RD, d. melanogaster
CG3525-RE, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		32585
FlyBaseiFBgn0000536, eas
VEuPathDBiVectorBase:FBgn0000536

Phylogenomic databases

eggNOGiKOG4720, Eukaryota
GeneTreeiENSGT00950000182939
InParanoidiP54352
OMAiWTVLQKW
PhylomeDBiP54352

Enzyme and pathway databases

UniPathwayiUPA00558;UER00741
ReactomeiR-DME-1483213, Synthesis of PE

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		32585, 0 hits in 3 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		32585

Protein Ontology

More...PROi		PR:P54352

Gene expression databases

ExpressionAtlasiP54352, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR011009, Kinase-like_dom_sf
SUPFAMiSSF56112, SSF56112, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiEAS_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P54352
Secondary accession number(s): C8VV66
, M9NEJ9, M9NGH8, Q1RL01, Q540Y9, Q86B51, Q8IR20, Q9VXI7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: March 24, 2009
Last modified: February 23, 2022
This is version 168 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families
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