UniProtKB - P54296 (MYOM2_HUMAN)

BLAST

>sp|P54296|MYOM2_HUMAN Myomesin-2 OS=Homo sapiens OX=9606 GN=MYOM2 PE=1 SV=2
MSLVTVPFYQKRHRHFDQSYRNIQTRYLLDEYASKKRASTQASSQKSLSQRSSSQRASSQ
TSLGGTICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAKRQRFLSELAHLEEDVHLARS
QARDKLDKYAIQQMMEDKLAWERHTFEERISRAPEILVRLRSHTVWERMSVKLCFTVQGF
PTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAHGQVST
NAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFLEKFGVTFRREGETVTLKCT
MLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSR
GGVSDHSAFLFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVD
RCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVAALDP
LDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGPPTGVHASEISRNYVVLSWEPPTPRGKD
PLMYFIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEIT
SPIQAQDVTVVPSAPGRVLASRNTKTSVVVQWDRPKHEEDLLGYYVDCCVAGTNLWEPCN
HKPIGYNRFVVHGLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLL
NCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSL
YEFKIAAVNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSG
SSPVSGYFVDFREEDAGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSD
TSEPVLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIET
VGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKS
ELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSEIHRIKCDKATGIIEMVMDRF
SIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEFQRKEFLRKQGPHFAEYLHWDV
TEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNLERGICELLIPKLSKKDHGEYKA
TLKDDRGQDVSILEIAGKVYDDMILAMSRVCGKSASPLKVLCTPEGIRLQCFMKYFTDEM
KVNWCHKDAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSG
QAFDEAFAEFQQFKAAAFAEKNRGRLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFK
NDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGE
KIPDMAPPQQAKPKLIPASASAAGQ

Align
Format
Add to basket Added to basket
History
Entry version 155 (07 Nov 2018)
Sequence version 2 (03 Mar 2009)
Previous versions | rss
Other tutorials and videos
Help video
Feedback

Protein

Myomesin-2

Gene

MYOM2

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.

GO - Molecular functionⁱ

actin filament binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
kinase binding
Source: CAFA
Inferred from physical interactionⁱ
- 12972258
muscle alpha-actinin binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
structural constituent of muscle
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cardiac muscle fiber development
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
cardiac muscle tissue morphogenesis
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
cardiac myofibril assembly
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
extraocular skeletal muscle development Source: Ensembl
muscle contraction
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
sarcomere organization
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
skeletal muscle myosin thick filament assembly
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
skeletal muscle thin filament assembly
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Muscle protein

Molecular function

Muscle protein

Enzyme and pathway databases

SIGNORⁱ	P54296

SIGNORⁱ

P54296

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Myomesin-2 Alternative name(s): 165 kDa connectin-associated protein 165 kDa titin-associated protein M-protein Myomesin family member 2
Gene namesⁱ	Name:MYOM2
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 8

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000036448.9
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:7614 MYOM2
MIMⁱ	603509 gene
neXtProtⁱ	NX_P54296

Keywords - Cellular componentⁱ

Cytoplasm, Thick filament

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	9172
PharmGKBⁱ	PA31419

Polymorphism and mutation databases

BioMutaⁱ	MYOM2
DMDMⁱ	224471842

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000072686	1 – 1465	Myomesin-2Add BLAST		1465

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P54296
PaxDbⁱ	P54296
PeptideAtlas More...PeptideAtlasⁱ	P54296
PRIDEⁱ	P54296
ProteomicsDBⁱ	56680

PTM databases

iPTMnetⁱ	P54296
PhosphoSitePlusⁱ	P54296

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000036448 Expressed in 168 organ(s), highest expression level in apex of heart
CleanExⁱ	HS_MYOM2
ExpressionAtlasⁱ	P54296 baseline and differential
Genevisibleⁱ	P54296 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA001765 HPA005953

HPAⁱ

HPA001765
HPA005953

Interactionⁱ

Subunit structureⁱ

Interacts with TTN/titin.By similarity

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
ACTN2	P35609	2	EBI-5357134,EBI-77797
DYSF	O75923	3	EBI-5357134,EBI-2799016
RYR1	P21817	2	EBI-5357134,EBI-1221290
TTN	Q8WZ42	2	EBI-5357134,EBI-681210

GO - Molecular functionⁱ

actin filament binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
kinase binding
Source: CAFA
Inferred from physical interactionⁱ
- 12972258
muscle alpha-actinin binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	114612, 2 interactors
IntActⁱ	P54296, 14 interactors
STRINGⁱ	9606.ENSP00000262113

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P54296
SMRⁱ	P54296
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	154 – 245	Ig-like C2-type 1Add BLAST	92
Domainⁱ	266 – 371	Ig-like C2-type 2Add BLAST	106
Domainⁱ	385 – 480	Fibronectin type-III 1PROSITE-ProRule annotationAdd BLAST	96
Domainⁱ	513 – 608	Fibronectin type-III 2PROSITE-ProRule annotationAdd BLAST	96
Domainⁱ	614 – 707	Fibronectin type-III 3PROSITE-ProRule annotationAdd BLAST	94
Domainⁱ	710 – 812	Fibronectin type-III 4PROSITE-ProRule annotationAdd BLAST	103
Domainⁱ	815 – 912	Fibronectin type-III 5PROSITE-ProRule annotationAdd BLAST	98
Domainⁱ	904 – 1002	Ig-like C2-type 3Add BLAST	99
Domainⁱ	1130 – 1211	Ig-like C2-type 4Add BLAST	82
Domainⁱ	1345 – 1434	Ig-like C2-type 5Add BLAST	90

Keywords - Domainⁱ

Immunoglobulin domain, Repeat

Phylogenomic databases

eggNOGⁱ	ENOG410IJ5G Eukaryota ENOG410ZSRR LUCA
HOGENOMⁱ	HOG000293283
HOVERGENⁱ	HBG004977
InParanoidⁱ	P54296
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G00GW
PhylomeDBⁱ	P54296
TreeFamⁱ	TF331825

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00063 FN3, 5 hits
Gene3Dⁱ	2.60.40.10, 12 hits
InterProⁱ	View protein in InterPro IPR003961 FN3_dom IPR036116 FN3_sf IPR007110 Ig-like_dom IPR036179 Ig-like_dom_sf IPR013783 Ig-like_fold IPR013098 Ig_I-set IPR003599 Ig_sub IPR003598 Ig_sub2
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00041 fn3, 5 hits PF07679 I-set, 3 hits
SMARTⁱ	View protein in SMART SM00060 FN3, 5 hits SM00409 IG, 5 hits SM00408 IGc2, 3 hits
SUPFAMⁱ	SSF48726 SSF48726, 6 hits SSF49265 SSF49265, 3 hits
PROSITEⁱ	View protein in PROSITE PS50853 FN3, 5 hits PS50835 IG_LIKE, 4 hits

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show all Align All

P54296-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSLVTVPFYQ KRHRHFDQSY RNIQTRYLLD EYASKKRAST QASSQKSLSQ 
        60         70         80         90        100
RSSSQRASSQ TSLGGTICRV CAKRVSTQED EEQENRSRYQ SLVAAYGEAK 
       110        120        130        140        150
RQRFLSELAH LEEDVHLARS QARDKLDKYA IQQMMEDKLA WERHTFEERI 
       160        170        180        190        200
SRAPEILVRL RSHTVWERMS VKLCFTVQGF PTPVVQWYKD GSLICQAAEP 
       210        220        230        240        250
GKYRIESNYG VHTLEINRAD FDDTATYSAV ATNAHGQVST NAAVVVRRFR 
       260        270        280        290        300
GDEEPFRSVG LPIGLPLSSM IPYTHFDVQF LEKFGVTFRR EGETVTLKCT 
       310        320        330        340        350
MLVTPDLKRV QPRAEWYRDD VLLKESKWTK MFFGEGQASL SFSHLHKDDE 
       360        370        380        390        400
GLYTLRIVSR GGVSDHSAFL FVRDADPLVT GAPGAPMDLQ CHDANRDYVI 
       410        420        430        440        450
VTWKPPNTTT ESPVMGYFVD RCEVGTNNWV QCNDAPVKIC KYPVTGLFEG 
       460        470        480        490        500
RSYIFRVRAV NSAGISRPSR VSDAVAALDP LDLRRLQAVH LEGEKEIAIY 
       510        520        530        540        550
QDDLEGDAQV PGPPTGVHAS EISRNYVVLS WEPPTPRGKD PLMYFIEKSV 
       560        570        580        590        600
VGSGSWQRVN AQTAVRSPRY AVFDLMEGKS YVFRVLSANR HGLSEPSEIT 
       610        620        630        640        650
SPIQAQDVTV VPSAPGRVLA SRNTKTSVVV QWDRPKHEED LLGYYVDCCV 
       660        670        680        690        700
AGTNLWEPCN HKPIGYNRFV VHGLTTGEQY IFRVKAVNAV GMSENSQESD 
       710        720        730        740        750
VIKVQAALTV PSHPYGITLL NCDGHSMTLG WKVPKFSGGS PILGYYLDKR 
       760        770        780        790        800
EVHHKNWHEV NSSPSKPTIL TVDGLTEGSL YEFKIAAVNL AGIGEPSDPS 
       810        820        830        840        850
EHFKCEAWTM PEPGPAYDLT FCEVRDTSLV MLWKAPVYSG SSPVSGYFVD 
       860        870        880        890        900
FREEDAGEWI TVNQTTTANR YLKVSDLQQG KTYVFRVRAV NANGVGKPSD 
       910        920        930        940        950
TSEPVLVEAR PGTKEISAGV DEQGNIYLGF DCQEMTDASQ FTWCKSYEEI 
       960        970        980        990       1000
SDDERFKIET VGDHSKLYLK NPDKEDLGTY SVSVSDTDGV SSSFVLDPEE 
      1010       1020       1030       1040       1050
LERLMALSNE IKNPTIPLKS ELAYEIFDKG RVRFWLQAEH LSPDASYRFI 
      1060       1070       1080       1090       1100
INDREVSDSE IHRIKCDKAT GIIEMVMDRF SIENEGTYTV QIHDGKAKSQ 
      1110       1120       1130       1140       1150
SSLVLIGDAF KTVLEEAEFQ RKEFLRKQGP HFAEYLHWDV TEECEVRLVC 
      1160       1170       1180       1190       1200
KVANTKKETV FKWLKDDVLY ETETLPNLER GICELLIPKL SKKDHGEYKA 
      1210       1220       1230       1240       1250
TLKDDRGQDV SILEIAGKVY DDMILAMSRV CGKSASPLKV LCTPEGIRLQ 
      1260       1270       1280       1290       1300
CFMKYFTDEM KVNWCHKDAK ISSSEHMRIG GSEEMAWLQI CEPTEKDKGK 
      1310       1320       1330       1340       1350
YTFEIFDGKD NHQRSLDLSG QAFDEAFAEF QQFKAAAFAE KNRGRLIGGL 
      1360       1370       1380       1390       1400
PDVVTIMEGK TLNLTCTVFG NPDPEVIWFK NDQDIQLSEH FSVKVEQAKY 
      1410       1420       1430       1440       1450
VSMTIKGVTS EDSGKYSINI KNKYGGEKID VTVSVYKHGE KIPDMAPPQQ 
      1460 
AKPKLIPASA SAAGQ

Length:1,465

Mass (Da):164,896

Last modified:March 3, 2009 - v2

Checksum:ⁱ71C6B11FCB066A8B

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

E7EWH9	E7EWH9_HUMAN	Myomesin-2 Myomesin-2	MYOM2	890	Annotation score:
A0A0J9YVV7	A0A0J9YVV7_HUMAN	Myomesin-2 Myomesin-2	MYOM2	890	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	102 – 103	QR → HG in CAA48832 (PubMed:7505783).Curated	2
Sequence conflictⁱ	364	S → T in CAA48832 (PubMed:7505783).Curated	1
Sequence conflictⁱ	555	S → T in CAA48832 (PubMed:7505783).Curated	1
Sequence conflictⁱ	863	N → D in CAA48832 (PubMed:7505783).Curated	1

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_033613	81	E → K. Corresponds to variant dbSNP:rs35985218Ensembl.	1
Natural variantⁱVAR_033614	182	T → M. Corresponds to variant dbSNP:rs17064618Ensembl.	1
Natural variantⁱVAR_033615	321	V → L1 PublicationCorresponds to variant dbSNP:rs2272720Ensembl.	1
Natural variantⁱVAR_033616	363	V → I. Corresponds to variant dbSNP:rs34316994Ensembl.	1
Natural variantⁱVAR_033617	601	S → Y. Corresponds to variant dbSNP:rs36089594Ensembl.	1
Natural variantⁱVAR_033618	701	V → I. Corresponds to variant dbSNP:rs35335787Ensembl.	1
Natural variantⁱVAR_020083	776	T → M1 PublicationCorresponds to variant dbSNP:rs2294066Ensembl.	1
Natural variantⁱVAR_054501	869	N → S2 PublicationsCorresponds to variant dbSNP:rs968381Ensembl.	1
Natural variantⁱVAR_020084	1022	L → F. Corresponds to variant dbSNP:rs2280896Ensembl.	1
Natural variantⁱVAR_061320	1168	V → A2 PublicationsCorresponds to variant dbSNP:rs17854780Ensembl.	1
Natural variantⁱVAR_033619	1284	E → D. Corresponds to variant dbSNP:rs34735757Ensembl.	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X69089 mRNA Translation: CAA48832.1 AC125453 Genomic DNA No translation available. BC052969 mRNA Translation: AAH52969.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS5957.1
PIRⁱ	S43529
NCBI Reference Sequences More...RefSeqⁱ	NP_003961.3, NM_003970.3
UniGeneⁱ	Hs.443683

Genome annotation databases

Ensemblⁱ	ENST00000262113; ENSP00000262113; ENSG00000036448 ENST00000616680; ENSP00000478322; ENSG00000274137
GeneIDⁱ	9172
KEGGⁱ	hsa:9172
UCSC genome browser More...UCSCⁱ	uc033azy.2 human

Keywords - Coding sequence diversityⁱ

Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P54296	Myomesin-2		HUMAN		890	UniRef100_P54296

Protein	Similar proteins		Species	Score	Length	Source
P54296	Myomesin-2		HUMAN		890	UniRef90_P54296
Uncharacterized protein		MACMU		1470
Uncharacterized protein		CHLSB		1465
Uncharacterized protein		PANPA		1465
Myomesin 2		MACFA		1465
+56

Protein	Similar proteins		Species	Score	Length	Source
P54296	M-protein, striated muscle		CHICK		1450	UniRef50_P54296
Myomesin-2		HUMAN		890
Uncharacterized protein		MACMU		1470
Myomesin 2		SAIBB		1465
Uncharacterized protein		PANPA		1465
+321

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X69089 mRNA Translation: CAA48832.1 AC125453 Genomic DNA No translation available. BC052969 mRNA Translation: AAH52969.1
CCDSⁱ	CCDS5957.1
PIRⁱ	S43529
RefSeqⁱ	NP_003961.3, NM_003970.3
UniGeneⁱ	Hs.443683

3D structure databases

ProteinModelPortalⁱ	P54296
SMRⁱ	P54296
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	114612, 2 interactors
IntActⁱ	P54296, 14 interactors
STRINGⁱ	9606.ENSP00000262113

PTM databases

iPTMnetⁱ	P54296
PhosphoSitePlusⁱ	P54296

Polymorphism and mutation databases

BioMutaⁱ	MYOM2
DMDMⁱ	224471842

Proteomic databases

MaxQBⁱ	P54296
PaxDbⁱ	P54296
PeptideAtlasⁱ	P54296
PRIDEⁱ	P54296
ProteomicsDBⁱ	56680

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000262113; ENSP00000262113; ENSG00000036448 ENST00000616680; ENSP00000478322; ENSG00000274137
GeneIDⁱ	9172
KEGGⁱ	hsa:9172
UCSCⁱ	uc033azy.2 human

Organism-specific databases

CTDⁱ	9172
DisGeNETⁱ	9172
EuPathDBⁱ	HostDB:ENSG00000036448.9
GeneCardsⁱ	MYOM2
H-InvDBⁱ	HIX0025666
HGNCⁱ	HGNC:7614 MYOM2
HPAⁱ	HPA001765 HPA005953
MIMⁱ	603509 gene
neXtProtⁱ	NX_P54296
PharmGKBⁱ	PA31419
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IJ5G Eukaryota ENOG410ZSRR LUCA
HOGENOMⁱ	HOG000293283
HOVERGENⁱ	HBG004977
InParanoidⁱ	P54296
OrthoDBⁱ	EOG091G00GW
PhylomeDBⁱ	P54296
TreeFamⁱ	TF331825

Enzyme and pathway databases

SIGNORⁱ	P54296

SIGNORⁱ

P54296

Miscellaneous databases

ChiTaRSⁱ	MYOM2 human
GeneWikiⁱ	MYOM2
GenomeRNAiⁱ	9172
Protein Ontology More...PROⁱ	PR:P54296
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000036448 Expressed in 168 organ(s), highest expression level in apex of heart
CleanExⁱ	HS_MYOM2
ExpressionAtlasⁱ	P54296 baseline and differential
Genevisibleⁱ	P54296 HS

Family and domain databases

CDDⁱ	cd00063 FN3, 5 hits
Gene3Dⁱ	2.60.40.10, 12 hits
InterProⁱ	View protein in InterPro IPR003961 FN3_dom IPR036116 FN3_sf IPR007110 Ig-like_dom IPR036179 Ig-like_dom_sf IPR013783 Ig-like_fold IPR013098 Ig_I-set IPR003599 Ig_sub IPR003598 Ig_sub2
Pfamⁱ	View protein in Pfam PF00041 fn3, 5 hits PF07679 I-set, 3 hits
SMARTⁱ	View protein in SMART SM00060 FN3, 5 hits SM00409 IG, 5 hits SM00408 IGc2, 3 hits
SUPFAMⁱ	SSF48726 SSF48726, 6 hits SSF49265 SSF49265, 3 hits
PROSITEⁱ	View protein in PROSITE PS50853 FN3, 5 hits PS50835 IG_LIKE, 4 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	MYOM2_HUMAN
Accessionⁱ	P54296Primary (citable) accession number: P54296 Secondary accession number(s): Q7Z3Y2
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
	Last sequence update:	March 3, 2009
	Last modified:	November 7, 2018
	This is version 155 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome 8
Human chromosome 8: entries, gene names and cross-references to MIM

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P54296 (MYOM2_HUMAN)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Myomesin-2

MYOM2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Cytoskeleton

Mitochondrion

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ