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UniProtKB - P53959 (COG6_YEAST)
Protein
Conserved oligomeric Golgi complex subunit 6
Gene
COG6
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.
2 PublicationsMiscellaneous
Present with 1720 molecules/cell in log phase SD medium.1 Publication
GO - Biological processi
- cytoplasm to vacuole transport by the Cvt pathway Source: SGD
- intra-Golgi vesicle-mediated transport Source: SGD
Keywordsi
Biological process | Protein transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Conserved oligomeric Golgi complex subunit 6Short name: COG complex subunit 6 Alternative name(s): Complexed with DOR1 protein 2 Component of oligomeric Golgi complex 6 Protein SEC37 |
Gene namesi | Name:COG6 Synonyms:COD2, SEC37, TFI2 Ordered Locus Names:YNL041C ORF Names:N2675 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000004986, COG6 |
VEuPathDBi | FungiDB:YNL041C |
Subcellular locationi
Golgi apparatus
- Golgi apparatus membrane By similarity; Peripheral membrane protein By similarity
Golgi apparatus
- Golgi membrane Source: UniProtKB-SubCell
- Golgi transport complex Source: SGD
Keywords - Cellular componenti
Golgi apparatus, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000213517 | 1 – 839 | Conserved oligomeric Golgi complex subunit 6Add BLAST | 839 |
Proteomic databases
MaxQBi | P53959 |
PaxDbi | P53959 |
PRIDEi | P53959 |
PTM databases
iPTMneti | P53959 |
Interactioni
Subunit structurei
Component of the conserved oligomeric Golgi (COG or Sec34/Sec35) complex which consists of eight different proteins COG1-COG8.
3 PublicationsBinary interactionsi
P53959
Protein-protein interaction databases
BioGRIDi | 35783, 532 interactors |
ComplexPortali | CPX-1840, COG Golgi transport complex |
DIPi | DIP-4373N |
IntActi | P53959, 18 interactors |
MINTi | P53959 |
STRINGi | 4932.YNL041C |
Miscellaneous databases
RNActi | P53959, protein |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 14 – 38 | DisorderedSequence analysisAdd BLAST | 25 |
Sequence similaritiesi
Belongs to the COG6 family.Curated
Phylogenomic databases
eggNOGi | KOG3758, Eukaryota |
GeneTreei | ENSGT00390000013518 |
HOGENOMi | CLU_017837_0_0_1 |
InParanoidi | P53959 |
OMAi | INCFDLI |
Family and domain databases
InterProi | View protein in InterPro IPR010490, COG6 |
PANTHERi | PTHR21506, PTHR21506, 1 hit |
Pfami | View protein in Pfam PF06419, COG6, 1 hit |
SMARTi | View protein in SMART SM01087, COG6, 1 hit |
i Sequence
Sequence statusi: Complete.
P53959-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDFVVDYQTY AMADTATPEL PEPEPRLNLT SDAQSQPTGK LDLQFKLPDL
60 70 80 90 100
QRYSNNNATL PVDNDGAGSK DLHKKMTHYA MSSIDKIQLS NPSKQLGQNS
110 120 130 140 150
QDEKLSQQES QNFTNYEPKN LDLSKLVSPS SGSNKNTTNL VLSNKLSKIL
160 170 180 190 200
NNYTLINYQA TVQLRKSLKV LEENKERLSL DEQKLMNPEY VGTLARRALR
210 220 230 240 250
TDLESQLLKE HITVLEEFKP IIRRIKRLSS SVEKIQRTSE KLLSNETNEV
260 270 280 290 300
PTNNVVLQEI DQYRLKAEQL KLKKKILLSI RDRFTLNQVE DDVITNGTID
310 320 330 340 350
NIFFEVVKKV INIKDESSFL LTLPNLNAGN ALIMGVNEIL EKTNKKIFNY
360 370 380 390 400
LIDFLYSFES SSNLLNDHGT TEQESLNIFR KSLVFLSSDL ELFNELLKRV
410 420 430 440 450
TTLRSKSILD EFLSQFDMNS TTSKPIILSA HDPIRYIGDV LASVHSIIAN
460 470 480 490 500
EADFVKSLFD FQDEDLKDTP ISILQQNKTF LKGIDNKLLN DIIQSLSNSC
510 520 530 540 550
RIRIEQIVRF EENPIINFEI VRLLKLYRVM FERKGIQDDS SIINNLKSLE
560 570 580 590 600
DISKNRIIGY YEDYMKQTVM AETKNSSDDL LPPEWLSEYM NKLVELFEIY
610 620 630 640 650
EKTHAAEDEE SEDNKLLSSK NLQTIVEQPI KDVLLKQLQT SFPLAKKNEK
660 670 680 690 700
EKASLLTIEI NCFDLIKSRL QPFEGLFAQD DDSRKITIWV CDKLKEYTKQ
710 720 730 740 750
MLTLQIKFLF ENTGLDLYSN LVNMIFPVDS VKDELDYDMY LALRDNSLME
760 770 780 790 800
LDMVRKNVHD KLNYYLPQAL TDVQGNLLFK LTSPMIADEI CDECFKKLSL
810 820 830
FYNIFRKLLI HLYPNKKDQV FEILNFSTDE FDMLIGIDH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z71317 Genomic DNA Translation: CAA95908.1 BK006947 Genomic DNA Translation: DAA10504.1 |
PIRi | S62963 |
RefSeqi | NP_014357.1, NM_001182880.1 |
Genome annotation databases
EnsemblFungii | YNL041C_mRNA; YNL041C; YNL041C |
GeneIDi | 855687 |
KEGGi | sce:YNL041C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z71317 Genomic DNA Translation: CAA95908.1 BK006947 Genomic DNA Translation: DAA10504.1 |
PIRi | S62963 |
RefSeqi | NP_014357.1, NM_001182880.1 |
3D structure databases
SMRi | P53959 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 35783, 532 interactors |
ComplexPortali | CPX-1840, COG Golgi transport complex |
DIPi | DIP-4373N |
IntActi | P53959, 18 interactors |
MINTi | P53959 |
STRINGi | 4932.YNL041C |
PTM databases
iPTMneti | P53959 |
Proteomic databases
MaxQBi | P53959 |
PaxDbi | P53959 |
PRIDEi | P53959 |
Genome annotation databases
EnsemblFungii | YNL041C_mRNA; YNL041C; YNL041C |
GeneIDi | 855687 |
KEGGi | sce:YNL041C |
Organism-specific databases
SGDi | S000004986, COG6 |
VEuPathDBi | FungiDB:YNL041C |
Phylogenomic databases
eggNOGi | KOG3758, Eukaryota |
GeneTreei | ENSGT00390000013518 |
HOGENOMi | CLU_017837_0_0_1 |
InParanoidi | P53959 |
OMAi | INCFDLI |
Miscellaneous databases
PROi | PR:P53959 |
RNActi | P53959, protein |
Family and domain databases
InterProi | View protein in InterPro IPR010490, COG6 |
PANTHERi | PTHR21506, PTHR21506, 1 hit |
Pfami | View protein in Pfam PF06419, COG6, 1 hit |
SMARTi | View protein in SMART SM01087, COG6, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | COG6_YEAST | |
Accessioni | P53959Primary (citable) accession number: P53959 Secondary accession number(s): D6W1D8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1996 |
Last sequence update: | October 1, 1996 | |
Last modified: | February 23, 2022 | |
This is version 161 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome XIV
Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names - SIMILARITY comments
Index of protein domains and families