UniProtKB - P53851 (TEX1_YEAST)
Protein
Protein TEX1
Gene
TEX1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Component the TREX complex, which operates in coupling transcription elongation to mRNA export.
GO - Molecular functioni
- mRNA binding Source: SGD
GO - Biological processi
- mRNA export from nucleus Source: GO_Central
Keywordsi
Biological process | Transcription, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: Protein TEX1Alternative name(s): Trex component 1 |
Gene namesi | Name:TEX1 Ordered Locus Names:YNL253W ORF Names:N0860 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:YNL253W |
SGDi | S000005197, TEX1 |
Subcellular locationi
Nucleus
- Nucleus Curated
Nucleus
- THO complex part of transcription export complex Source: GO_Central
- transcription export complex Source: SGD
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000051482 | 1 – 422 | Protein TEX1Add BLAST | 422 |
Proteomic databases
MaxQBi | P53851 |
PaxDbi | P53851 |
PRIDEi | P53851 |
PTM databases
CarbonylDBi | P53851 |
iPTMneti | P53851 |
Interactioni
Subunit structurei
Component of the transcription/export (TREX) complex, which is at least is formed of SUB2, TEX1 and YRA1 and the THO complex composed of HPR1, MFT1, THO2 and THP1.
1 PublicationProtein-protein interaction databases
BioGRIDi | 35586, 70 interactors |
ComplexPortali | CPX-1792, THO complex CPX-1793, TREX complex |
DIPi | DIP-2820N |
IntActi | P53851, 9 interactors |
MINTi | P53851 |
STRINGi | 4932.YNL253W |
Miscellaneous databases
RNActi | P53851, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 61 – 100 | WD 1Add BLAST | 40 | |
Repeati | 158 – 197 | WD 2Add BLAST | 40 | |
Repeati | 207 – 246 | WD 3Add BLAST | 40 | |
Repeati | 251 – 290 | WD 4Add BLAST | 40 | |
Repeati | 293 – 332 | WD 5Add BLAST | 40 |
Keywords - Domaini
Repeat, WD repeatPhylogenomic databases
eggNOGi | KOG4155, Eukaryota |
HOGENOMi | CLU_041466_0_0_1 |
InParanoidi | P53851 |
OMAi | HASHTTC |
Family and domain databases
Gene3Di | 2.130.10.10, 2 hits |
InterProi | View protein in InterPro IPR040132, Tex1/THOC3 IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR017986, WD40_repeat_dom IPR036322, WD40_repeat_dom_sf |
PANTHERi | PTHR22839, PTHR22839, 1 hit |
Pfami | View protein in Pfam PF00400, WD40, 1 hit |
SMARTi | View protein in SMART SM00320, WD40, 5 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS50082, WD_REPEATS_2, 1 hit PS50294, WD_REPEATS_REGION, 1 hit |
i Sequence
Sequence statusi: Complete.
P53851-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSTIGAVDIL NQKTITSEVA ASVTSKYLQS TFSKGNTSHI EDKRFIHVSS
60 70 80 90 100
RSHSRFTSTP ITPNEILSLK FHVSGSSMAY SRMDGSLTVW FIKDASFDKS
110 120 130 140 150
VEVYIPDCCG SDKLATDLSW NPTSLNQIAV VSNSSEISLL LINEKSLTAS
160 170 180 190 200
KLRTLSLGSK TKVNTCLYDP LGNWLLAATK SEKIYLFDVK KDHSSVCSLN
210 220 230 240 250
ISDISQEDND VVYSLAWSNG GSHIFIGFKS GYLAILKAKH GILEVCTKIK
260 270 280 290 300
AHTGPITEIK MDPWGRNFIT GSIDGNCYVW NMKSLCCELI INDLNSAVTT
310 320 330 340 350
LDVCHLGKIL GICTEDEMVY FYDLNSGNLL HSKSLANYKT DPVLKFYPDK
360 370 380 390 400
SWYIMSGKND TLSNHFVKNE KNLITYWKDM FDNTMIEKRR KNNGGGNNHN
410 420
KRTSKNTDRI GKDRPSRFNS KK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z71529 Genomic DNA Translation: CAA96160.1 X96722 Genomic DNA Translation: CAA65491.1 AY558028 Genomic DNA Translation: AAS56354.1 BK006947 Genomic DNA Translation: DAA10306.1 |
PIRi | S63226 |
RefSeqi | NP_014146.1, NM_001183091.1 |
Genome annotation databases
EnsemblFungii | YNL253W_mRNA; YNL253W; YNL253W |
GeneIDi | 855468 |
KEGGi | sce:YNL253W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z71529 Genomic DNA Translation: CAA96160.1 X96722 Genomic DNA Translation: CAA65491.1 AY558028 Genomic DNA Translation: AAS56354.1 BK006947 Genomic DNA Translation: DAA10306.1 |
PIRi | S63226 |
RefSeqi | NP_014146.1, NM_001183091.1 |
3D structure databases
SMRi | P53851 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 35586, 70 interactors |
ComplexPortali | CPX-1792, THO complex CPX-1793, TREX complex |
DIPi | DIP-2820N |
IntActi | P53851, 9 interactors |
MINTi | P53851 |
STRINGi | 4932.YNL253W |
PTM databases
CarbonylDBi | P53851 |
iPTMneti | P53851 |
Proteomic databases
MaxQBi | P53851 |
PaxDbi | P53851 |
PRIDEi | P53851 |
Genome annotation databases
EnsemblFungii | YNL253W_mRNA; YNL253W; YNL253W |
GeneIDi | 855468 |
KEGGi | sce:YNL253W |
Organism-specific databases
EuPathDBi | FungiDB:YNL253W |
SGDi | S000005197, TEX1 |
Phylogenomic databases
eggNOGi | KOG4155, Eukaryota |
HOGENOMi | CLU_041466_0_0_1 |
InParanoidi | P53851 |
OMAi | HASHTTC |
Miscellaneous databases
PROi | PR:P53851 |
RNActi | P53851, protein |
Family and domain databases
Gene3Di | 2.130.10.10, 2 hits |
InterProi | View protein in InterPro IPR040132, Tex1/THOC3 IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR017986, WD40_repeat_dom IPR036322, WD40_repeat_dom_sf |
PANTHERi | PTHR22839, PTHR22839, 1 hit |
Pfami | View protein in Pfam PF00400, WD40, 1 hit |
SMARTi | View protein in SMART SM00320, WD40, 5 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS50082, WD_REPEATS_2, 1 hit PS50294, WD_REPEATS_REGION, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TEX1_YEAST | |
Accessioni | P53851Primary (citable) accession number: P53851 Secondary accession number(s): D6W0U0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1996 |
Last sequence update: | October 1, 1996 | |
Last modified: | December 2, 2020 | |
This is version 167 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast chromosome XIV
Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names - Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD