UniProtKB - P53703 (CCHL_CAEEL)
Protein
Probable holocytochrome-c-type synthase
Gene
cchl-1
Organism
Caenorhabditis elegans
Status
Functioni
Probable lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.By similarity
Catalytic activityi
GO - Molecular functioni
- holocytochrome-c synthase activity Source: GO_Central
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- cytochrome c-heme linkage Source: GO_Central
Keywordsi
Molecular function | Lyase |
Ligand | Heme, Iron, Metal-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Probable holocytochrome-c-type synthaseBy similarity (EC:4.4.1.17By similarity)Alternative name(s): Cytochrome c-type heme lyaseBy similarity Short name: CCHLBy similarity |
Gene namesi | Name:cchl-1 ORF Names:T06D8.6 |
Organismi | Caenorhabditis elegans |
Taxonomic identifieri | 6239 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditina › Rhabditomorpha › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis |
Proteomesi |
|
Organism-specific databases
WormBasei | T06D8.6 ; CE02327 ; WBGene00011527 ; cchl-1 |
Subcellular locationi
Mitochondrion
- Mitochondrion inner membrane By similarity
Mitochondrion
- mitochondrial inner membrane Source: UniProtKB-SubCell
- mitochondrion Source: WormBase
Keywords - Cellular componenti
Membrane, Mitochondrion, Mitochondrion inner membranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000121714 | 1 – 280 | Probable holocytochrome-c-type synthaseAdd BLAST | 280 |
Proteomic databases
EPDi | P53703 |
PaxDbi | P53703 |
PeptideAtlasi | P53703 |
Expressioni
Gene expression databases
Bgeei | WBGene00011527, Expressed in germ line (C elegans) and 5 other tissues |
Interactioni
Protein-protein interaction databases
BioGRIDi | 40022, 4 interactors |
STRINGi | 6239.T06D8.6.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 35 – 40 | HRM 1 | 6 | |
Repeati | 56 – 61 | HRM 2 | 6 |
Sequence similaritiesi
Belongs to the cytochrome c-type heme lyase family.Curated
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | KOG3996, Eukaryota |
GeneTreei | ENSGT00390000004175 |
HOGENOMi | CLU_048602_2_0_1 |
InParanoidi | P53703 |
OMAi | YPSKFGT |
OrthoDBi | 1282808at2759 |
PhylomeDBi | P53703 |
Family and domain databases
InterProi | View protein in InterPro IPR000511, Cyt_C/C1_haem_lyase |
PANTHERi | PTHR12743, PTHR12743, 1 hit |
Pfami | View protein in Pfam PF01265, Cyto_heme_lyase, 1 hit |
PROSITEi | View protein in PROSITE PS00821, CYTO_HEME_LYASE_1, 1 hit PS00822, CYTO_HEME_LYASE_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P53703-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGSSQSTPKV QDANADAERI RKAQHSMAAA GGGSQCPLTP EQRAAASGEN
60 70 80 90 100
CGAGGACPVG ADKASINPLN NELEHPNQKP APDQPFALPT KREKSTIPKA
110 120 130 140 150
GTETETWTYP SPQMFWNAML KKGWRWQDDS LSKSDMENII SIHNANNEEA
160 170 180 190 200
WREVLKWENL LHPECAEPKL KSFKGDAKNL SPRARFRNLF LGYDLPFDRH
210 220 230 240 250
DWIVDRCGTK QVQYVIDYYD GGAVDPSSKL FTILDVRPAV NDIGNIWDRM
260 270 280
VVAYWRFKFE TLGFTPSLPI PPTEGHNVNH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z49130 Genomic DNA Translation: CAA88969.1 |
PIRi | T24579 |
RefSeqi | NP_496403.1, NM_064002.5 |
Genome annotation databases
EnsemblMetazoai | T06D8.6.1; T06D8.6.1; WBGene00011527 T06D8.6.2; T06D8.6.2; WBGene00011527 |
GeneIDi | 174713 |
KEGGi | cel:CELE_T06D8.6 |
UCSCi | T06D8.6.1, c. elegans |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z49130 Genomic DNA Translation: CAA88969.1 |
PIRi | T24579 |
RefSeqi | NP_496403.1, NM_064002.5 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 40022, 4 interactors |
STRINGi | 6239.T06D8.6.1 |
Proteomic databases
EPDi | P53703 |
PaxDbi | P53703 |
PeptideAtlasi | P53703 |
Genome annotation databases
EnsemblMetazoai | T06D8.6.1; T06D8.6.1; WBGene00011527 T06D8.6.2; T06D8.6.2; WBGene00011527 |
GeneIDi | 174713 |
KEGGi | cel:CELE_T06D8.6 |
UCSCi | T06D8.6.1, c. elegans |
Organism-specific databases
CTDi | 174713 |
WormBasei | T06D8.6 ; CE02327 ; WBGene00011527 ; cchl-1 |
Phylogenomic databases
eggNOGi | KOG3996, Eukaryota |
GeneTreei | ENSGT00390000004175 |
HOGENOMi | CLU_048602_2_0_1 |
InParanoidi | P53703 |
OMAi | YPSKFGT |
OrthoDBi | 1282808at2759 |
PhylomeDBi | P53703 |
Miscellaneous databases
PROi | PR:P53703 |
Gene expression databases
Bgeei | WBGene00011527, Expressed in germ line (C elegans) and 5 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR000511, Cyt_C/C1_haem_lyase |
PANTHERi | PTHR12743, PTHR12743, 1 hit |
Pfami | View protein in Pfam PF01265, Cyto_heme_lyase, 1 hit |
PROSITEi | View protein in PROSITE PS00821, CYTO_HEME_LYASE_1, 1 hit PS00822, CYTO_HEME_LYASE_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CCHL_CAEEL | |
Accessioni | P53703Primary (citable) accession number: P53703 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1996 |
Last sequence update: | October 1, 1996 | |
Last modified: | February 10, 2021 | |
This is version 117 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Caenorhabditis annotation project |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Caenorhabditis elegans
Caenorhabditis elegans: entries, gene names and cross-references to WormBase - SIMILARITY comments
Index of protein domains and families