UniProtKB - P53435 (GLPD_MYCLE)
Protein
Glycerol-3-phosphate dehydrogenase
Gene
glpD
Organism
Mycobacterium leprae (strain TN)
Status
Functioni
Catalytic activityi
- EC:1.1.5.3
Cofactori
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 37 – 65 | FADBy similarityAdd BLAST | 29 |
GO - Molecular functioni
- sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC
GO - Biological processi
- glycerol-3-phosphate metabolic process Source: InterPro
- glycerol metabolic process Source: UniProtKB-KW
Keywordsi
Molecular function | Oxidoreductase |
Biological process | Glycerol metabolism |
Ligand | FAD, Flavoprotein |
Enzyme and pathway databases
BioCyci | MLEP272631:G1GT5-781-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:glpD Ordered Locus Names:ML0713 ORF Names:L308_C1_179 |
Organismi | Mycobacterium leprae (strain TN) |
Taxonomic identifieri | 272631 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycobacterium › |
Proteomesi |
|
Organism-specific databases
Lepromai | ML0713 |
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm By similarity
Other locations
- glycerol-3-phosphate dehydrogenase complex Source: InterPro
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000126099 | 1 – 585 | Glycerol-3-phosphate dehydrogenaseAdd BLAST | 585 |
Family & Domainsi
Sequence similaritiesi
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.Curated
Phylogenomic databases
eggNOGi | COG0578, Bacteria |
HOGENOMi | CLU_015740_5_1_11 |
OMAi | AHGFSKT |
Family and domain databases
Gene3Di | 1.10.8.870, 1 hit 3.50.50.60, 1 hit |
InterProi | View protein in InterPro IPR031656, DAO_C IPR038299, DAO_C_sf IPR006076, FAD-dep_OxRdtase IPR036188, FAD/NAD-bd_sf IPR000447, G3P_DH_FAD-dep |
PANTHERi | PTHR11985, PTHR11985, 1 hit |
Pfami | View protein in Pfam PF01266, DAO, 1 hit PF16901, DAO_C, 1 hit |
PRINTSi | PR01001, FADG3PDH |
SUPFAMi | SSF51905, SSF51905, 1 hit |
PROSITEi | View protein in PROSITE PS00977, FAD_G3PDH_1, 1 hit PS00978, FAD_G3PDH_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P53435-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTDLIQAPES EQTWPASALG PQQRAAAWER FGTEQFDVVV IGGGVVGSGC
60 70 80 90 100
ALDAATRGLK VALVEARDLA SGTSSRSSKM FHGGLRYLEQ LEFGLVREAL
110 120 130 140 150
YERELSLTTL APHLVKPLPF LFPLTKRWWE RPYIAAGIFL YDRLGGAKSV
160 170 180 190 200
PAQKHLTRAG ALRLSPGLKR SSLIGGIRYY DTVVDDARHT LTVARTAAHY
210 220 230 240 250
GAVVRCSTQV VALLREGDRV IGVRVRDSED GAVTEIRGHV VVNATGVWTD
260 270 280 290 300
EIQALSKQRG RFQVRVSKGV HVVVPRDRIV SDVAMILRTK KSVMFIIPWG
310 320 330 340 350
NHWIIGTTDT DWNLDLAHPA ATKADIDYIL QTVNTVLATP LTHADIDGVY
360 370 380 390 400
AGLRPLLAGE SDDTSKLTRE HAVAVPVAGL VAIAGGKYTT YRVMAADAID
410 420 430 440 450
AAVAFVPARV APSITEKVGL LGADGYFALI NQVEHVAALQ GLHPYRVRHL
460 470 480 490 500
LDRYGALIGD VLALAAEAPD LLSPIQEAPG YLKVEARYAV TAEGALHLED
510 520 530 540 550
ILARRMRVSI EYPHRGVACA REVADVVAPV LGWTAEDIDR EVATYNARVE
560 570 580
AEVLSQAQPD DVSADMLRAS APEARTKIIE PVSLT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00022 Genomic DNA Translation: AAA17328.1 AL583919 Genomic DNA Translation: CAC30222.1 |
PIRi | S73029 |
RefSeqi | NP_301564.1, NC_002677.1 WP_010907888.1, NC_002677.1 |
Genome annotation databases
EnsemblBacteriai | CAC30222; CAC30222; CAC30222 |
KEGGi | mle:ML0713 |
PATRICi | fig|272631.5.peg.1287 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00022 Genomic DNA Translation: AAA17328.1 AL583919 Genomic DNA Translation: CAC30222.1 |
PIRi | S73029 |
RefSeqi | NP_301564.1, NC_002677.1 WP_010907888.1, NC_002677.1 |
3D structure databases
SMRi | P53435 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 272631.ML0713 |
Genome annotation databases
EnsemblBacteriai | CAC30222; CAC30222; CAC30222 |
KEGGi | mle:ML0713 |
PATRICi | fig|272631.5.peg.1287 |
Organism-specific databases
Lepromai | ML0713 |
Phylogenomic databases
eggNOGi | COG0578, Bacteria |
HOGENOMi | CLU_015740_5_1_11 |
OMAi | AHGFSKT |
Enzyme and pathway databases
BioCyci | MLEP272631:G1GT5-781-MONOMER |
Family and domain databases
Gene3Di | 1.10.8.870, 1 hit 3.50.50.60, 1 hit |
InterProi | View protein in InterPro IPR031656, DAO_C IPR038299, DAO_C_sf IPR006076, FAD-dep_OxRdtase IPR036188, FAD/NAD-bd_sf IPR000447, G3P_DH_FAD-dep |
PANTHERi | PTHR11985, PTHR11985, 1 hit |
Pfami | View protein in Pfam PF01266, DAO, 1 hit PF16901, DAO_C, 1 hit |
PRINTSi | PR01001, FADG3PDH |
SUPFAMi | SSF51905, SSF51905, 1 hit |
PROSITEi | View protein in PROSITE PS00977, FAD_G3PDH_1, 1 hit PS00978, FAD_G3PDH_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | GLPD_MYCLE | |
Accessioni | P53435Primary (citable) accession number: P53435 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1996 |
Last sequence update: | October 1, 1996 | |
Last modified: | December 2, 2020 | |
This is version 113 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families