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Protein

Glycerol-3-phosphate dehydrogenase

Gene

glpD

Organism
Mycobacterium leprae (strain TN)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

Cofactori

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi37 – 65FADBy similarityAdd BLAST29

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processGlycerol metabolism
LigandFAD, Flavoprotein

Enzyme and pathway databases

BioCyciMLEP272631:G1GT5-781-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase (EC:1.1.5.3)
Gene namesi
Name:glpD
Ordered Locus Names:ML0713
ORF Names:L308_C1_179
OrganismiMycobacterium leprae (strain TN)
Taxonomic identifieri272631 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000000806 Componenti: Chromosome

Organism-specific databases

LepromaiML0713

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001260991 – 585Glycerol-3-phosphate dehydrogenaseAdd BLAST585

Proteomic databases

PRIDEiP53435

Interactioni

Protein-protein interaction databases

STRINGi272631.ML0713

Structurei

3D structure databases

ProteinModelPortaliP53435
SMRiP53435
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105C6V Bacteria
COG0578 LUCA
HOGENOMiHOG000004813
KOiK00111
OMAiVPYYWVG
OrthoDBiPOG091H04DP

Family and domain databases

Gene3Di1.10.8.870, 1 hit
3.50.50.60, 3 hits
InterProiView protein in InterPro
IPR031656 DAO_C
IPR038299 DAO_C_sf
IPR006076 FAD-dep_OxRdtase
IPR036188 FAD/NAD-bd_sf
IPR000447 G3P_DH_FAD-dep
PANTHERiPTHR11985 PTHR11985, 1 hit
PfamiView protein in Pfam
PF01266 DAO, 1 hit
PF16901 DAO_C, 1 hit
PRINTSiPR01001 FADG3PDH
SUPFAMiSSF51905 SSF51905, 2 hits
PROSITEiView protein in PROSITE
PS00977 FAD_G3PDH_1, 1 hit
PS00978 FAD_G3PDH_2, 1 hit

Sequencei

Sequence statusi: Complete.

P53435-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDLIQAPES EQTWPASALG PQQRAAAWER FGTEQFDVVV IGGGVVGSGC
60 70 80 90 100
ALDAATRGLK VALVEARDLA SGTSSRSSKM FHGGLRYLEQ LEFGLVREAL
110 120 130 140 150
YERELSLTTL APHLVKPLPF LFPLTKRWWE RPYIAAGIFL YDRLGGAKSV
160 170 180 190 200
PAQKHLTRAG ALRLSPGLKR SSLIGGIRYY DTVVDDARHT LTVARTAAHY
210 220 230 240 250
GAVVRCSTQV VALLREGDRV IGVRVRDSED GAVTEIRGHV VVNATGVWTD
260 270 280 290 300
EIQALSKQRG RFQVRVSKGV HVVVPRDRIV SDVAMILRTK KSVMFIIPWG
310 320 330 340 350
NHWIIGTTDT DWNLDLAHPA ATKADIDYIL QTVNTVLATP LTHADIDGVY
360 370 380 390 400
AGLRPLLAGE SDDTSKLTRE HAVAVPVAGL VAIAGGKYTT YRVMAADAID
410 420 430 440 450
AAVAFVPARV APSITEKVGL LGADGYFALI NQVEHVAALQ GLHPYRVRHL
460 470 480 490 500
LDRYGALIGD VLALAAEAPD LLSPIQEAPG YLKVEARYAV TAEGALHLED
510 520 530 540 550
ILARRMRVSI EYPHRGVACA REVADVVAPV LGWTAEDIDR EVATYNARVE
560 570 580
AEVLSQAQPD DVSADMLRAS APEARTKIIE PVSLT
Length:585
Mass (Da):63,373
Last modified:October 1, 1996 - v1
Checksum:i4B468DD09C1C70F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00022 Genomic DNA Translation: AAA17328.1
AL583919 Genomic DNA Translation: CAC30222.1
PIRiS73029
RefSeqiNP_301564.1, NC_002677.1
WP_010907888.1, NC_002677.1

Genome annotation databases

EnsemblBacteriaiCAC30222; CAC30222; CAC30222
GeneIDi909648
KEGGimle:ML0713
PATRICifig|272631.5.peg.1287

Similar proteinsi

Entry informationi

Entry nameiGLPD_MYCLE
AccessioniPrimary (citable) accession number: P53435
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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