Kinesin-like protein KIP3

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

Miscellaneous

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• ATP binding Source: UniProtKB-KW
• ATP-dependent microtubule motor activity, plus-end-directed Source: SGD <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 16906145
  • 16906148
• microtubule binding Source: InterPro
• tubulin-dependent ATPase activity Source: SGDInferred from direct assayⁱ
  • 16906148

GO - Biological processⁱ

• establishment of mitotic spindle orientation Source: SGD <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypeⁱ
  • 16906148
  • 9281582
• mitotic spindle assembly Source: SGDInferred from mutant phenotypeⁱ
  • 23851487
• mitotic spindle disassembly Source: SGDInferred from mutant phenotypeⁱ
  • 23851487
  • 9813090
• mitotic spindle organization Source: SGDInferred from mutant phenotypeⁱ
  • 10525539
• negative regulation of microtubule polymerization Source: SGDInferred from mutant phenotypeⁱ
  • 24616221
• nuclear migration along microtubule Source: SGDInferred from mutant phenotypeⁱ
  • 9693366
• plus-end specific microtubule depolymerization Source: SGDInferred from direct assayⁱ
  • 16906145
  • 16906148
• regulation of mitotic spindle elongation Source: SGDInferred from mutant phenotypeⁱ
  • 24616221

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

Keywords - Cellular componentⁱ

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

GO - Molecular functionⁱ

• microtubule binding Source: InterPro

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MNVPETRQSS IVVAIRVRPF TSMEKTRLVN EASGAEANFP GLGDSSLILP 
        60         70         80         90        100
MSNNSDSDID IDAEEGSTRS KRNSLLRRKV IRPEGIRKIV DCVDDRMLIF 
       110        120        130        140        150
DPADRNPLNK VSDQVLNSMR ARATKATASS INNSNATNKF SSQRRRHGGE 
       160        170        180        190        200
IKFVFDKLFD ETSSQARVYK ETTSPLLDSV LDGFNSTVFA YGATGCGKTY 
       210        220        230        240        250
TVSGTPSQPG IIFLAMEELF NKITDLKDEK DFEISLSYLE IYNERIRDLL 
       260        270        280        290        300
KPETPSKRLV IREDTQNHIK VANLSYHHPN TVEDVMDLVV QGNINRTTSP 
       310        320        330        340        350
TEANEVSSRS HAVLQIHIMQ TNKLVDLTSQ HTFATLSIID LAGSERAAAT 
       360        370        380        390        400
RNRGIRLHEG ANINRSLLAL GNCINALCLN DGSRSCHIPY RDSKLTRLLK 
       410        420        430        440        450
FSLGGNCKTV MIVCISPSSS HYDETLNTLK YANRAKEIKT KIIRNQQSLS 
       460        470        480        490        500
RHVGSYLKMI TEQKRQIEEL REREEKMISL KLTKYKLNKE KIQLAINECV 
       510        520        530        540        550
NRVQQTYAGV ETYQVAKTLK SLILCKRRFL QMVKLEVDNL ILLFEREEST 
       560        570        580        590        600
AAEMQPVISN CRMISGQLYN KIHELEMKFD ETDTLSSVIH QVHSIDLNKL 
       610        620        630        640        650
REMEDWDETY DLVYLESCLN QISELQRNEI LVNSSIMTEK LMSDPGLNSR 
       660        670        680        690        700
FKFLSKWLMN RTPNIESIIQ DLVHIDEEFE SFARTFIANP DSNFTNTNIN 
       710        720        730        740        750
IINTTAADLA VPAETLQRQN FSQKKVKWTS PDLSPSPMIE PQPELEPELH 
       760        770        780        790        800
QDQDAIASEV DVSMQDTTFN EQGPSTPSAP TTAVPRRKMR SSLLTHQSLL 

ATARK                                                  

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 100% Identity
• 90% Identity
• 50% Identity

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ