UniProtKB - P53032 (SUT1_YEAST)
Protein
Sterol uptake protein 1
Gene
SUT1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Transcription factor involved in the induction of hypoxic gene transcription when the cells are shifted from aerobiosis to anaerobiosis. Involved in sterol uptake.2 Publications
Miscellaneous
Present with 1100 molecules/cell in log phase SD medium.1 Publication
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: InterPro
- RNA polymerase II repressing transcription factor binding Source: SGD
- zinc ion binding Source: InterPro
GO - Biological processi
- negative regulation of transcription by RNA polymerase II Source: SGD
- negative regulation of transcription from RNA polymerase II promoter by pheromones Source: SGD
- positive regulation of transcription by RNA polymerase II Source: SGD
Keywordsi
Biological process | Transcription, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: Sterol uptake protein 1 |
Gene namesi | Name:SUT1 Ordered Locus Names:YGL162W ORF Names:G1828 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000003130, SUT1 |
VEuPathDBi | FungiDB:YGL162W |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000115014 | 1 – 299 | Sterol uptake protein 1Add BLAST | 299 |
Proteomic databases
MaxQBi | P53032 |
PaxDbi | P53032 |
PRIDEi | P53032 |
PTM databases
iPTMneti | P53032 |
Interactioni
Subunit structurei
Interacts with SSN6/CYC8.
1 PublicationGO - Molecular functioni
Protein-protein interaction databases
BioGRIDi | 33091, 98 interactors |
DIPi | DIP-5748N |
IntActi | P53032, 10 interactors |
MINTi | P53032 |
STRINGi | 4932.YGL162W |
Miscellaneous databases
RNActi | P53032, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the SUT1 family.Curated
Phylogenomic databases
eggNOGi | ENOG502S235, Eukaryota |
GeneTreei | ENSGT00940000176592 |
HOGENOMi | CLU_051216_0_0_1 |
InParanoidi | P53032 |
OMAi | ADSNECA |
Family and domain databases
CDDi | cd00067, GAL4, 1 hit |
InterProi | View protein in InterPro IPR001138, Zn2-C6_fun-type_DNA-bd IPR036864, Zn2-C6_fun-type_DNA-bd_sf |
SUPFAMi | SSF57701, SSF57701, 1 hit |
i Sequence
Sequence statusi: Complete.
P53032-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSTSITVRNR DRSLPPLLLP NVSLLEKDIR RKGTQNVGIT DPELLSTTWT
60 70 80 90 100
RKRAFPTDEL LGGYKRLKPA AADSNECAIG IATVTPPPTL PVSAIVPPPQ
110 120 130 140 150
NYTPPLFEYH PHALASMVNE DANASCTQMS IISRSTSNST TSSATSTSSI
160 170 180 190 200
SKRQRSGPSC DKCRLKKIKC NAKIEILLQD DTIMPMISNK LRYVLTPDDI
210 220 230 240 250
RLYRGTLLRN IAIPDDVIEG TGSRKLIKHI DKLVLLTPCL PCIKKKHSSS
260 270 280 290
STNFPKNDKC TFSKGFTRAD INISSKISLK FKDKTIYDIT YDDYKSIDF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X77766 Genomic DNA Translation: CAA54806.1 Z48618 Genomic DNA No translation available. Z72684 Genomic DNA Translation: CAA96874.1 BK006941 Genomic DNA Translation: DAA07950.1 |
PIRi | JC4374 |
RefSeqi | NP_011353.1, NM_001181027.1 |
Genome annotation databases
EnsemblFungii | YGL162W_mRNA; YGL162W; YGL162W |
GeneIDi | 852714 |
KEGGi | sce:YGL162W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X77766 Genomic DNA Translation: CAA54806.1 Z48618 Genomic DNA No translation available. Z72684 Genomic DNA Translation: CAA96874.1 BK006941 Genomic DNA Translation: DAA07950.1 |
PIRi | JC4374 |
RefSeqi | NP_011353.1, NM_001181027.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 33091, 98 interactors |
DIPi | DIP-5748N |
IntActi | P53032, 10 interactors |
MINTi | P53032 |
STRINGi | 4932.YGL162W |
PTM databases
iPTMneti | P53032 |
Proteomic databases
MaxQBi | P53032 |
PaxDbi | P53032 |
PRIDEi | P53032 |
Genome annotation databases
EnsemblFungii | YGL162W_mRNA; YGL162W; YGL162W |
GeneIDi | 852714 |
KEGGi | sce:YGL162W |
Organism-specific databases
SGDi | S000003130, SUT1 |
VEuPathDBi | FungiDB:YGL162W |
Phylogenomic databases
eggNOGi | ENOG502S235, Eukaryota |
GeneTreei | ENSGT00940000176592 |
HOGENOMi | CLU_051216_0_0_1 |
InParanoidi | P53032 |
OMAi | ADSNECA |
Miscellaneous databases
PROi | PR:P53032 |
RNActi | P53032, protein |
Family and domain databases
CDDi | cd00067, GAL4, 1 hit |
InterProi | View protein in InterPro IPR001138, Zn2-C6_fun-type_DNA-bd IPR036864, Zn2-C6_fun-type_DNA-bd_sf |
SUPFAMi | SSF57701, SSF57701, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SUT1_YEAST | |
Accessioni | P53032Primary (citable) accession number: P53032 Secondary accession number(s): D6VTY9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1996 |
Last sequence update: | October 1, 1996 | |
Last modified: | February 10, 2021 | |
This is version 141 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - SIMILARITY comments
Index of protein domains and families - Yeast chromosome VII
Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names