UniProtKB - P52869 (EAEA_HAFAL)
Protein
Intimin
Gene
eaeA
Organism
Hafnia alvei
Status
Functioni
Necessary for the production of attaching and effacing lesions on tissue culture cells.
GO - Biological processi
- pathogenesis Source: UniProtKB-KW
Keywordsi
Biological process | Virulence |
Names & Taxonomyi
Protein namesi | Recommended name: IntiminAlternative name(s): Attaching and effacing protein Outer membrane protein |
Gene namesi | Name:eaeA Synonyms:eae |
Organismi | Hafnia alvei |
Taxonomic identifieri | 569 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Hafniaceae › Hafnia |
Subcellular locationi
- Cell outer membrane By similarity; Single-pass membrane protein By similarity
GO - Cellular componenti
- cell outer membrane Source: UniProtKB-SubCell
- integral component of membrane Source: UniProtKB-KW
Keywords - Cellular componenti
Cell outer membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000211829 | ‹1 – 280 | IntiminAdd BLAST | ›280 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 92 | Big-1PROSITE-ProRule annotationAdd BLAST | 92 | |
Domaini | 127 – 173 | BIG2Sequence analysisAdd BLAST | 47 |
Sequence similaritiesi
Belongs to the intimin/invasin family.Curated
Keywords - Domaini
TransmembraneFamily and domain databases
Gene3Di | 2.60.40.10, 1 hit 3.10.100.10, 1 hit |
InterProi | View protein in InterPro IPR003344, Big_1_dom IPR003343, Big_2 IPR016186, C-type_lectin-like/link_sf IPR016187, CTDL_fold IPR013783, Ig-like_fold IPR013117, Intimin_C IPR008964, Invasin/intimin_cell_adhesion |
Pfami | View protein in Pfam PF02369, Big_1, 1 hit PF02368, Big_2, 1 hit PF07979, Intimin_C, 1 hit |
SMARTi | View protein in SMART SM00634, BID_1, 1 hit SM00635, BID_2, 1 hit |
SUPFAMi | SSF49373, SSF49373, 2 hits SSF56436, SSF56436, 1 hit |
PROSITEi | View protein in PROSITE PS51127, BIG1, 1 hit |
i Sequence
Sequence statusi: Fragment.
P52869-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
ITEIKADKTT AVANGKDAVT YTVKVMKDGK PLSGEEVTFT TTLGTLSKST
60 70 80 90 100
EKTNTNGYRK VSLTSANQGK SLVSASVTMP QLMLKLLEVE FFTQLTIDNG
110 120 130 140 150
NVEIVGTGAK GKLPNVWLQY GQVNLKANGG NGKYTWYSAN PAIASVDPSS
160 170 180 190 200
GQVTLKDKGE TTITVVSGDK QTAIYTIAMP NSIVSVNSSG RVDYNTANNI
210 220 230 240 250
CKNIKGSLPS SIKELKDLYD DWGAANKYQH YSQESITAWT LQTSENKVQG
260 270 280
VASTYDLVRK NPLIDKVDIA GNYAYAVCVK
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L29509 Genomic DNA Translation: AAA24937.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L29509 Genomic DNA Translation: AAA24937.1 |
3D structure databases
SMRi | P52869 |
ModBasei | Search... |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 3.10.100.10, 1 hit |
InterProi | View protein in InterPro IPR003344, Big_1_dom IPR003343, Big_2 IPR016186, C-type_lectin-like/link_sf IPR016187, CTDL_fold IPR013783, Ig-like_fold IPR013117, Intimin_C IPR008964, Invasin/intimin_cell_adhesion |
Pfami | View protein in Pfam PF02369, Big_1, 1 hit PF02368, Big_2, 1 hit PF07979, Intimin_C, 1 hit |
SMARTi | View protein in SMART SM00634, BID_1, 1 hit SM00635, BID_2, 1 hit |
SUPFAMi | SSF49373, SSF49373, 2 hits SSF56436, SSF56436, 1 hit |
PROSITEi | View protein in PROSITE PS51127, BIG1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | EAEA_HAFAL | |
Accessioni | P52869Primary (citable) accession number: P52869 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1996 |
Last sequence update: | October 1, 1996 | |
Last modified: | December 2, 2020 | |
This is version 75 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |