Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phase 2 flagellin

Gene

fljB

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.

Miscellaneous

Individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes.

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

BioCyciSENT99287:G1FZD-2798-MONOMER
ReactomeiR-GGA-433822 NFkB and MAPK activation mediated by TRAF6
R-GGA-451534 TLR5 cascade
R-GGA-977240 MyD88 cascade initiated on plasma membrane
R-HSA-844623 The IPAF inflammasome

Names & Taxonomyi

Protein namesi
Recommended name:
Phase 2 flagellin
Gene namesi
Name:fljB
Synonyms:H2
Ordered Locus Names:STM2771
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Bacterial flagellum, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001825802 – 506Phase 2 flagellinAdd BLAST505

Proteomic databases

PaxDbiP52616
PRIDEiP52616

Interactioni

Protein-protein interaction databases

STRINGi99287.STM2771

Structurei

3D structure databases

ProteinModelPortaliP52616
SMRiP52616
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial flagellin family.Curated

Phylogenomic databases

eggNOGiENOG4105I03 Bacteria
COG1344 LUCA
HOGENOMiHOG000255144
KOiK02406
OMAiFEHTINN
PhylomeDBiP52616

Family and domain databases

InterProiView protein in InterPro
IPR001492 Flagellin
IPR001029 Flagellin_D0/D1
IPR014981 Flagellin_D3
PfamiView protein in Pfam
PF00700 Flagellin_C, 1 hit
PF08884 Flagellin_D3, 1 hit
PF00669 Flagellin_N, 1 hit
PRINTSiPR00207 FLAGELLIN

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P52616-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQVINTNSL SLLTQNNLNK SQSALGTAIE RLSSGLRINS AKDDAAGQAI
60 70 80 90 100
ANRFTANIKG LTQASRNAND GISIAQTTEG ALNEINNNLQ RVRELAVQSA
110 120 130 140 150
NSTNSQSDLD SIQAEITQRL NEIDRVSGQT QFNGVKVLAQ DNTLTIQVGA
160 170 180 190 200
NDGETIDIDL KQINSQTLGL DSLNVQKAYD VKDTAVTTKA YANNGTTLDV
210 220 230 240 250
SGLDDAAIKA ATGGTNGTAS VTGGAVKFDA DNNKYFVTIG GFTGADAAKN
260 270 280 290 300
GDYEVNVATD GTVTLAAGAT KTTMPAGATT KTEVQELKDT PAVVSADAKN
310 320 330 340 350
ALIAGGVDAT DANGAELVKM SYTDKNGKTI EGGYALKAGD KYYAADYDEA
360 370 380 390 400
TGAIKAKTTS YTAADGTTKT AANQLGGVDG KTEVVTIDGK TYNASKAAGH
410 420 430 440 450
DFKAQPELAE AAAKTTENPL QKIDAALAQV DALRSDLGAV QNRFNSAITN
460 470 480 490 500
LGNTVNNLSE ARSRIEDSDY ATEVSNMSRA QILQQAGTSV LAQANQVPQN

VLSLLR
Length:506
Mass (Da):52,536
Last modified:January 23, 2007 - v2
Checksum:i3A4051A9AF7AF88B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti38I → S in CAA24655 (PubMed:6271461).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U17177 Genomic DNA Translation: AAC43354.1
AE006468 Genomic DNA Translation: AAL21657.1
V01370 Genomic DNA Translation: CAA24655.1
D26168 Genomic DNA Translation: BAA05156.1
RefSeqiNP_461698.1, NC_003197.2
WP_000079794.1, NC_003197.2

Genome annotation databases

EnsemblBacteriaiAAL21657; AAL21657; STM2771
GeneIDi1254294
KEGGistm:STM2771
PATRICifig|99287.12.peg.2923

Similar proteinsi

Entry informationi

Entry nameiFLJB_SALTY
AccessioniPrimary (citable) accession number: P52616
Secondary accession number(s): P97159
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 107 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health