UniProtKB - P52233 (THIO_ACIFR)
Protein
Thioredoxin
Gene
trxA
Organism
Acidithiobacillus ferrooxidans (Thiobacillus ferrooxidans)
Status
Functioni
Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
GO - Molecular functioni
- protein disulfide oxidoreductase activity Source: InterPro
GO - Biological processi
- cell redox homeostasis Source: InterPro
- glycerol ether metabolic process Source: InterPro
Keywordsi
Biological process | Electron transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: ThioredoxinShort name: Trx |
Gene namesi | Name:trxA |
Organismi | Acidithiobacillus ferrooxidans (Thiobacillus ferrooxidans) |
Taxonomic identifieri | 920 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Acidithiobacillia › Acidithiobacillales › Acidithiobacillaceae › Acidithiobacillus |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000120142 | 1 – 108 | ThioredoxinAdd BLAST | 108 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 33 ↔ 36 | Redox-activePROSITE-ProRule annotation |
Keywords - PTMi
Disulfide bondProteomic databases
PRIDEi | P52233 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 2 – 108 | ThioredoxinPROSITE-ProRule annotationAdd BLAST | 107 |
Sequence similaritiesi
Belongs to the thioredoxin family.Curated
Keywords - Domaini
Redox-active centerFamily and domain databases
Gene3Di | 3.40.30.10, 1 hit |
InterProi | View protein in InterPro IPR005746, Thioredoxin IPR036249, Thioredoxin-like_sf IPR017937, Thioredoxin_CS IPR013766, Thioredoxin_domain |
Pfami | View protein in Pfam PF00085, Thioredoxin, 1 hit |
PIRSFi | PIRSF000077, Thioredoxin, 1 hit |
SUPFAMi | SSF52833, SSF52833, 1 hit |
TIGRFAMsi | TIGR01068, thioredoxin, 1 hit |
PROSITEi | View protein in PROSITE PS00194, THIOREDOXIN_1, 1 hit PS51352, THIOREDOXIN_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P52233-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSDAILYVSD DSFETDVLKS SKPVLVDFWA EWCGPCKMIA PILEEIADEY
60 70 80 90 100
ADRLRVAKFN IDENPNTPPQ YAIRGIPTLL LFKAGKLEAT KVGALSKAQL
TAFLDSQL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U20361 Genomic DNA Translation: AAA88939.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U20361 Genomic DNA Translation: AAA88939.1 |
3D structure databases
SMRi | P52233 |
ModBasei | Search... |
Proteomic databases
PRIDEi | P52233 |
Family and domain databases
Gene3Di | 3.40.30.10, 1 hit |
InterProi | View protein in InterPro IPR005746, Thioredoxin IPR036249, Thioredoxin-like_sf IPR017937, Thioredoxin_CS IPR013766, Thioredoxin_domain |
Pfami | View protein in Pfam PF00085, Thioredoxin, 1 hit |
PIRSFi | PIRSF000077, Thioredoxin, 1 hit |
SUPFAMi | SSF52833, SSF52833, 1 hit |
TIGRFAMsi | TIGR01068, thioredoxin, 1 hit |
PROSITEi | View protein in PROSITE PS00194, THIOREDOXIN_1, 1 hit PS51352, THIOREDOXIN_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | THIO_ACIFR | |
Accessioni | P52233Primary (citable) accession number: P52233 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1996 |
Last sequence update: | October 1, 1996 | |
Last modified: | December 2, 2020 | |
This is version 86 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |