Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

NAD(P) transhydrogenase subunit alpha part 2

Gene

pntAB

Organism
Rickettsia prowazekii (strain Madrid E)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.By similarity

Catalytic activityi

NADPH + NAD+ = NADP+ + NADH.

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandNAD, NADP

Enzyme and pathway databases

BioCyciRPRO272947:G1GT0-866-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
NAD(P) transhydrogenase subunit alpha part 2 (EC:1.6.1.2)
Alternative name(s):
Nicotinamide nucleotide transhydrogenase subunit alpha 2
Pyridine nucleotide transhydrogenase subunit alpha 2
Gene namesi
Name:pntAB
Ordered Locus Names:RP862
OrganismiRickettsia prowazekii (strain Madrid E)
Taxonomic identifieri272947 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
Proteomesi
  • UP000002480 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei43 – 63HelicalSequence analysisAdd BLAST21
Transmembranei72 – 92HelicalSequence analysisAdd BLAST21
Transmembranei103 – 123HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001990221 – 132NAD(P) transhydrogenase subunit alpha part 2Add BLAST132

Interactioni

Subunit structurei

Complex of an alpha and a beta chain; in Rickettsia, the alpha chain seems to be made of two subunits.

Protein-protein interaction databases

STRINGi272947.RP862

Structurei

3D structure databases

ProteinModelPortaliP51995
SMRiP51995
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105W8H Bacteria
COG3288 LUCA
HOGENOMiHOG000253038
KOiK00324
OMAiFVVTDRM

Family and domain databases

InterProiView protein in InterPro
IPR024605 NADP_transhyd_a_C
PfamiView protein in Pfam
PF12769 PNTB_4TM, 1 hit

Sequencei

Sequence statusi: Complete.

P51995-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNQLPIMAKQ AAEIASNAQE LSNKLKDLVI DASWQTNTNT IDPLVFAITI
60 70 80 90 100
FVLASFVGYY VVWKVTPALH TPLMSITNAI SGIIVISSMI AITSSSAFEF
110 120 130
SSLLGSFATL LASINIFGGF IVTTRMLEMF KK
Length:132
Mass (Da):14,325
Last modified:May 30, 2000 - v2
Checksum:i8A56163C9F394F0D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U02878 Unassigned DNA No translation available.
AJ235273 Genomic DNA Translation: CAA15286.1
PIRiF71648
RefSeqiNP_221210.1, NC_000963.1
WP_004596754.1, NC_000963.1

Genome annotation databases

EnsemblBacteriaiCAA15286; CAA15286; CAA15286
GeneIDi883350
KEGGirpr:RP862
PATRICifig|272947.5.peg.901

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U02878 Unassigned DNA No translation available.
AJ235273 Genomic DNA Translation: CAA15286.1
PIRiF71648
RefSeqiNP_221210.1, NC_000963.1
WP_004596754.1, NC_000963.1

3D structure databases

ProteinModelPortaliP51995
SMRiP51995
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272947.RP862

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAA15286; CAA15286; CAA15286
GeneIDi883350
KEGGirpr:RP862
PATRICifig|272947.5.peg.901

Phylogenomic databases

eggNOGiENOG4105W8H Bacteria
COG3288 LUCA
HOGENOMiHOG000253038
KOiK00324
OMAiFVVTDRM

Enzyme and pathway databases

BioCyciRPRO272947:G1GT0-866-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR024605 NADP_transhyd_a_C
PfamiView protein in Pfam
PF12769 PNTB_4TM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPNTAB_RICPR
AccessioniPrimary (citable) accession number: P51995
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: May 30, 2000
Last modified: February 28, 2018
This is version 85 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Rickettsia prowazekii
    Rickettsia prowazekii (strain Madrid E): entries and gene names
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again