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Protein

V-type proton ATPase subunit d 1

Gene

Atp6v0d1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity).By similarity1 Publication

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=0.31 mM for ATP1 Publication

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    • protein-containing complex binding Source: MGI
    • proton-exporting ATPase activity, phosphorylative mechanism Source: MGI
    • proton-transporting ATPase activity, rotational mechanism Source: GO_Central

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Biological processCilium biogenesis/degradation, Hydrogen ion transport, Ion transport, Transport

    Enzyme and pathway databases

    Reactome - a knowledgebase of biological pathways and processes

    More...
    Reactomei
    R-MMU-1222556 ROS, RNS production in phagocytes
    R-MMU-77387 Insulin receptor recycling
    R-MMU-917977 Transferrin endocytosis and recycling
    R-MMU-983712 Ion channel transport

    Protein family/group databases

    Transport Classification Database

    More...
    TCDBi
    3.A.2.2.6 the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    V-type proton ATPase subunit d 1
    Short name:
    V-ATPase subunit d 1
    Alternative name(s):
    P39
    Physophilin
    V-ATPase 40 kDa accessory protein
    V-ATPase AC39 subunit
    Vacuolar proton pump subunit d 1
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:Atp6v0d1
    Synonyms:Atp6d
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

    Organism-specific databases

    Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

    More...
    MGIi
    MGI:1201778 Atp6v0d1

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

    Keywords - Cellular componenti

    Membrane

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001193511 – 351V-type proton ATPase subunit d 1Add BLAST351

    Amino acid modifications

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei270PhosphotyrosineCombined sources1
    Modified residuei283PhosphoserineCombined sources1

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    Encyclopedia of Proteome Dynamics

    More...
    EPDi
    P51863

    MaxQB - The MaxQuant DataBase

    More...
    MaxQBi
    P51863

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    P51863

    PeptideAtlas

    More...
    PeptideAtlasi
    P51863

    PRoteomics IDEntifications database

    More...
    PRIDEi
    P51863

    PTM databases

    iPTMnet integrated resource for PTMs in systems biology context

    More...
    iPTMneti
    P51863

    Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

    More...
    PhosphoSitePlusi
    P51863

    SwissPalm database of S-palmitoylation events

    More...
    SwissPalmi
    P51863

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

    Ubiquitous.2 Publications

    <p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

    Expressed throughout early development.1 Publication

    Gene expression databases

    Bgee dataBase for Gene Expression Evolution

    More...
    Bgeei
    ENSMUSG00000013160 Expressed in 307 organ(s), highest expression level in ear

    CleanEx database of gene expression profiles

    More...
    CleanExi
    MM_ATP6V0D1

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    P51863 MM

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    <p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

    V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d).

    Protein-protein interaction databases

    The Biological General Repository for Interaction Datasets (BioGrid)

    More...
    BioGridi
    198264, 6 interactors

    Protein interaction database and analysis system

    More...
    IntActi
    P51863, 9 interactors

    Molecular INTeraction database

    More...
    MINTi
    P51863

    STRING: functional protein association networks

    More...
    STRINGi
    10090.ENSMUSP00000013304

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    3D structure databases

    Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

    More...
    ProteinModelPortali
    P51863

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    <p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the V-ATPase V0D/AC39 subunit family.Curated

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG2957 Eukaryota
    COG1527 LUCA

    Ensembl GeneTree

    More...
    GeneTreei
    ENSGT00390000002200

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    HOG000199065

    The HOVERGEN Database of Homologous Vertebrate Genes

    More...
    HOVERGENi
    HBG018065

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    P51863

    KEGG Orthology (KO)

    More...
    KOi
    K02146

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    FMDFITY

    Database of Orthologous Groups

    More...
    OrthoDBi
    EOG091G09L5

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    P51863

    TreeFam database of animal gene trees

    More...
    TreeFami
    TF300857

    Family and domain databases

    Gene3D Structural and Functional Annotation of Protein Families

    More...
    Gene3Di
    1.20.1690.10, 2 hits

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR036079 ATPase_su_C-like
    IPR002843 ATPase_V0-cplx_csu/dsu
    IPR016727 ATPase_V0-cplx_dsu
    IPR035067 V-type_ATPase_suC

    The PANTHER Classification System

    More...
    PANTHERi
    PTHR11028 PTHR11028, 1 hit

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF01992 vATP-synt_AC39, 1 hit

    PIRSF; a whole-protein classification database

    More...
    PIRSFi
    PIRSF018497 V-ATP_synth_D, 1 hit

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF103486 SSF103486, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    P51863-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MSFFPELYFN VDNGYLEGLV RGLKAGVLSQ ADYLNLVQCE TLEDLKLHLQ
    60 70 80 90 100
    STDYGNFLAN EASPLTVSVI DDKLKEKMVV EFRHMRNHAY EPLASFLDFI
    110 120 130 140 150
    TYSYMIDNVI LLITGTLHQR SIAELVPKCH PLGSFEQMEA VNIAQTPAEL
    160 170 180 190 200
    YNAILVDTPL AAFFQDCISE QDLDEMNIEI IRNTLYKAYL ESFYKFCTLL
    210 220 230 240 250
    GGTTADAMCP ILEFEADRRA FIITINSFGT ELSKEDRAKL FPHCGRLYPE
    260 270 280 290 300
    GLAQLARADD YEQVKNVADY YPEYKLLFEG AGSNPGDKTL EDRFFEHEVK
    310 320 330 340 350
    LNKLAFLNQF HFGVFYAFVK LKEQECRNIV WIAECIAQRH RAKIDNYIPI

    F
    Length:351
    Mass (Da):40,301
    Last modified:January 11, 2001 - v2
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i62CDF67B982124C9
    GO

    Experimental Info

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti23L → M in AAC83085 (Ref. 1) Curated1

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    U13840 mRNA Translation: AAC83085.1
    U21549 mRNA Translation: AAA92288.1
    AB088408 mRNA Translation: BAC57954.1
    AK083372 mRNA Translation: BAC38889.1
    AK171515 mRNA Translation: BAE42500.1

    The Consensus CDS (CCDS) project

    More...
    CCDSi
    CCDS22604.1

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_038505.2, NM_013477.3

    UniGene gene-oriented nucleotide sequence clusters

    More...
    UniGenei
    Mm.17708

    Genome annotation databases

    Ensembl eukaryotic genome annotation project

    More...
    Ensembli
    ENSMUST00000013304; ENSMUSP00000013304; ENSMUSG00000013160

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    11972

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    mmu:11972

    UCSC genome browser

    More...
    UCSCi
    uc009ndg.1 mouse

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    U13840 mRNA Translation: AAC83085.1
    U21549 mRNA Translation: AAA92288.1
    AB088408 mRNA Translation: BAC57954.1
    AK083372 mRNA Translation: BAC38889.1
    AK171515 mRNA Translation: BAE42500.1
    CCDSiCCDS22604.1
    RefSeqiNP_038505.2, NM_013477.3
    UniGeneiMm.17708

    3D structure databases

    ProteinModelPortaliP51863
    ModBaseiSearch...
    MobiDBiSearch...

    Protein-protein interaction databases

    BioGridi198264, 6 interactors
    IntActiP51863, 9 interactors
    MINTiP51863
    STRINGi10090.ENSMUSP00000013304

    Protein family/group databases

    TCDBi3.A.2.2.6 the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily

    PTM databases

    iPTMnetiP51863
    PhosphoSitePlusiP51863
    SwissPalmiP51863

    Proteomic databases

    EPDiP51863
    MaxQBiP51863
    PaxDbiP51863
    PeptideAtlasiP51863
    PRIDEiP51863

    Protocols and materials databases

    Structural Biology KnowledgebaseSearch...

    Genome annotation databases

    EnsembliENSMUST00000013304; ENSMUSP00000013304; ENSMUSG00000013160
    GeneIDi11972
    KEGGimmu:11972
    UCSCiuc009ndg.1 mouse

    Organism-specific databases

    Comparative Toxicogenomics Database

    More...
    CTDi
    9114
    MGIiMGI:1201778 Atp6v0d1

    Phylogenomic databases

    eggNOGiKOG2957 Eukaryota
    COG1527 LUCA
    GeneTreeiENSGT00390000002200
    HOGENOMiHOG000199065
    HOVERGENiHBG018065
    InParanoidiP51863
    KOiK02146
    OMAiFMDFITY
    OrthoDBiEOG091G09L5
    PhylomeDBiP51863
    TreeFamiTF300857

    Enzyme and pathway databases

    ReactomeiR-MMU-1222556 ROS, RNS production in phagocytes
    R-MMU-77387 Insulin receptor recycling
    R-MMU-917977 Transferrin endocytosis and recycling
    R-MMU-983712 Ion channel transport

    Miscellaneous databases

    ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

    More...
    ChiTaRSi
    Atp6v0d1 mouse

    Protein Ontology

    More...
    PROi
    PR:P51863

    The Stanford Online Universal Resource for Clones and ESTs

    More...
    SOURCEi
    Search...

    Gene expression databases

    BgeeiENSMUSG00000013160 Expressed in 307 organ(s), highest expression level in ear
    CleanExiMM_ATP6V0D1
    GenevisibleiP51863 MM

    Family and domain databases

    Gene3Di1.20.1690.10, 2 hits
    InterProiView protein in InterPro
    IPR036079 ATPase_su_C-like
    IPR002843 ATPase_V0-cplx_csu/dsu
    IPR016727 ATPase_V0-cplx_dsu
    IPR035067 V-type_ATPase_suC
    PANTHERiPTHR11028 PTHR11028, 1 hit
    PfamiView protein in Pfam
    PF01992 vATP-synt_AC39, 1 hit
    PIRSFiPIRSF018497 V-ATP_synth_D, 1 hit
    SUPFAMiSSF103486 SSF103486, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiVA0D1_MOUSE
    <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P51863
    Secondary accession number(s): Q54A57, Q9QWJ2
    <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: January 11, 2001
    Last modified: November 7, 2018
    This is version 155 of the entry and version 2 of the sequence. See complete history.
    <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    <p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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