UniProtKB - P51692 (STA5B_HUMAN)
Protein
Signal transducer and activator of transcription 5B
Gene
STAT5B
Organism
Homo sapiens (Human)
Status
Functioni
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation.2 Publications
Caution
It was reported that dephosphorylation on tyrosine residues by PTPN2 would negatively regulate prolactin signaling pathway (PubMed:11773439). However, the corresponding article has been retracted (PubMed:24319783).1 Publication1 Publication
GO - Molecular functioni
- chromatin binding Source: UniProtKB
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: GO_Central
- DNA-binding transcription factor activity Source: ProtInc
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: NTNU_SB
- glucocorticoid receptor binding Source: BHF-UCL
- identical protein binding Source: IntAct
- protein dimerization activity Source: UniProtKB
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- cellular response to epidermal growth factor stimulus Source: UniProtKB
- cellular response to growth factor stimulus Source: UniProtKB
- cellular response to hormone stimulus Source: BHF-UCL
- cytokine-mediated signaling pathway Source: GO_Central
- defense response Source: GO_Central
- development of secondary female sexual characteristics Source: Ensembl
- development of secondary male sexual characteristics Source: Ensembl
- female pregnancy Source: Ensembl
- growth hormone receptor signaling pathway via JAK-STAT Source: BHF-UCL
- interleukin-15-mediated signaling pathway Source: Reactome
- interleukin-2-mediated signaling pathway Source: Reactome
- interleukin-7-mediated signaling pathway Source: Reactome
- interleukin-9-mediated signaling pathway Source: Reactome
- lactation Source: Ensembl
- lipid storage Source: Ensembl
- luteinization Source: Ensembl
- mast cell migration Source: Ensembl
- natural killer cell differentiation Source: Ensembl
- negative regulation of apoptotic process Source: Ensembl
- negative regulation of erythrocyte differentiation Source: Ensembl
- Peyer's patch development Source: Ensembl
- positive regulation of activated T cell proliferation Source: Ensembl
- positive regulation of B cell differentiation Source: Ensembl
- positive regulation of erythrocyte differentiation Source: UniProtKB
- positive regulation of gamma-delta T cell differentiation Source: Ensembl
- positive regulation of inflammatory response Source: Ensembl
- positive regulation of interleukin-2 production Source: Ensembl
- positive regulation of mitotic cell cycle Source: Ensembl
- positive regulation of multicellular organism growth Source: Ensembl
- positive regulation of natural killer cell differentiation Source: Ensembl
- positive regulation of natural killer cell mediated cytotoxicity Source: Ensembl
- positive regulation of natural killer cell proliferation Source: Ensembl
- positive regulation of transcription by RNA polymerase II Source: UniProtKB
- progesterone metabolic process Source: Ensembl
- receptor signaling pathway via JAK-STAT Source: GO_Central
- regulation of cell population proliferation Source: GO_Central
- regulation of epithelial cell differentiation Source: Ensembl
- regulation of multicellular organism growth Source: BHF-UCL
- regulation of steroid metabolic process Source: Ensembl
- regulation of transcription by RNA polymerase II Source: ProtInc
- response to estradiol Source: BHF-UCL
- response to interleukin-4 Source: Ensembl
- response to peptide hormone Source: GO_Central
- taurine metabolic process Source: BHF-UCL
- T cell differentiation in thymus Source: Ensembl
- T cell homeostasis Source: Ensembl
Keywordsi
Molecular function | Activator, DNA-binding |
Biological process | Transcription, Transcription regulation |
Enzyme and pathway databases
PathwayCommonsi | P51692 |
Reactomei | R-HSA-1170546, Prolactin receptor signaling R-HSA-1266695, Interleukin-7 signaling R-HSA-1433557, Signaling by SCF-KIT R-HSA-1839117, Signaling by cytosolic FGFR1 fusion mutants R-HSA-186763, Downstream signal transduction R-HSA-2586552, Signaling by Leptin R-HSA-512988, Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-8854691, Interleukin-20 family signaling R-HSA-8983432, Interleukin-15 signaling R-HSA-8985947, Interleukin-9 signaling R-HSA-9020558, Interleukin-2 signaling R-HSA-9020958, Interleukin-21 signaling R-HSA-9027283, Erythropoietin activates STAT5 R-HSA-9645135, STAT5 Activation R-HSA-9670439, Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-982772, Growth hormone receptor signaling |
SignaLinki | P51692 |
SIGNORi | P51692 |
Names & Taxonomyi
Protein namesi | Recommended name: Signal transducer and activator of transcription 5B |
Gene namesi | Name:STAT5B |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000173757.9 |
HGNCi | HGNC:11367, STAT5B |
MIMi | 604260, gene |
neXtProti | NX_P51692 |
Subcellular locationi
Cytosol
- cytosol Source: GO_Central
Nucleus
- nuclear chromatin Source: NTNU_SB
- nucleoplasm Source: Reactome
- nucleus Source: UniProtKB
Other locations
- cytoplasm Source: UniProtKB
Keywords - Cellular componenti
Cytoplasm, NucleusPathology & Biotechi
Involvement in diseasei
Growth hormone insensitivity with immunodeficiency (GHII)3 Publications
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA disease characterized by short stature, growth hormone deficiency in the presence of normal to elevated circulating concentrations of growth hormone, resistance to exogeneous growth hormone therapy, and recurrent infections.
Related information in OMIMFeature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_018728 | 630 | A → P in GHII; affects activation by growth hormone or interferon-gamma. 1 PublicationCorresponds to variant dbSNP:rs121908501EnsemblClinVar. | 1 | |
Natural variantiVAR_067368 | 646 | F → S in GHII; transcriptionally inactive. 1 Publication | 1 |
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 684 | T → A: Abolishes interaction with INSR. 1 Publication | 1 | |
Mutagenesisi | 699 | Y → F: Abolishes phosphorylation by HCK. 1 Publication | 1 |
Keywords - Diseasei
Disease mutation, DwarfismOrganism-specific databases
DisGeNETi | 6777 |
MalaCardsi | STAT5B |
MIMi | 245590, phenotype |
OpenTargetsi | ENSG00000173757 |
Orphaneti | 520, Acute promyelocytic leukemia 220465, Laron syndrome with immunodeficiency |
PharmGKBi | PA36186 |
Miscellaneous databases
Pharosi | P51692, Tchem |
Chemistry databases
ChEMBLi | CHEMBL5817 |
DrugBanki | DB01254, Dasatinib |
Polymorphism and mutation databases
BioMutai | STAT5B |
DMDMi | 41019536 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000182429 | 1 – 787 | Signal transducer and activator of transcription 5BAdd BLAST | 787 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 90 | PhosphotyrosineCombined sources | 1 | |
Modified residuei | 128 | PhosphoserineCombined sources | 1 | |
Modified residuei | 193 | PhosphoserineCombined sources | 1 | |
Modified residuei | 682 | PhosphotyrosineBy similarity | 1 | |
Modified residuei | 699 | Phosphotyrosine; by HCK, JAK and PTK62 Publications | 1 |
Post-translational modificationi
Tyrosine phosphorylated in response to signaling via activated KIT, resulting in translocation to the nucleus. Tyrosine phosphorylated in response to signaling via activated FLT3; wild-type FLT3 results in much weaker phosphorylation than constitutively activated mutant FLT3. Alternatively, can be phosphorylated by JAK2. Phosphorylation at Tyr-699 by PTK6 or HCK leads to an increase of its transcriptional activity.6 Publications
Keywords - PTMi
PhosphoproteinProteomic databases
CPTACi | CPTAC-1638 |
EPDi | P51692 |
jPOSTi | P51692 |
MassIVEi | P51692 |
MaxQBi | P51692 |
PaxDbi | P51692 |
PeptideAtlasi | P51692 |
PRIDEi | P51692 |
ProteomicsDBi | 56378 |
PTM databases
iPTMneti | P51692 |
PhosphoSitePlusi | P51692 |
Expressioni
Gene expression databases
Bgeei | ENSG00000173757, Expressed in blood and 247 other tissues |
ExpressionAtlasi | P51692, baseline and differential |
Genevisiblei | P51692, HS |
Organism-specific databases
HPAi | ENSG00000173757, Low tissue specificity |
Interactioni
Subunit structurei
Forms a homodimer or a heterodimer with a related family member. Binds NR3C1 (By similarity).
Interacts with NCOA1 (PubMed:12954634).
Interacts with NMI (PubMed:9989503).
Interacts with SOCS7 (PubMed:15677474).
Interacts (via SH2 domain) with INSR (PubMed:9428692).
Interacts with CPEB3; this inhibits STAT5B-mediated transcriptional activation (PubMed:20639532).
By similarity5 PublicationsBinary interactionsi
Hide detailsP51692
GO - Molecular functioni
- glucocorticoid receptor binding Source: BHF-UCL
- identical protein binding Source: IntAct
- protein dimerization activity Source: UniProtKB
Protein-protein interaction databases
BioGRIDi | 112654, 76 interactors |
CORUMi | P51692 |
IntActi | P51692, 117 interactors |
MINTi | P51692 |
STRINGi | 9606.ENSP00000293328 |
Chemistry databases
BindingDBi | P51692 |
Miscellaneous databases
RNActi | P51692, protein |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P51692 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 589 – 686 | SH2PROSITE-ProRule annotationAdd BLAST | 98 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 232 – 321 | Required for interaction with NMI1 PublicationAdd BLAST | 90 |
Sequence similaritiesi
Belongs to the transcription factor STAT family.Curated
Keywords - Domaini
SH2 domainPhylogenomic databases
eggNOGi | KOG3667, Eukaryota |
GeneTreei | ENSGT00990000203570 |
HOGENOMi | CLU_014189_2_2_1 |
InParanoidi | P51692 |
OMAi | IWLNRQQ |
OrthoDBi | 327469at2759 |
PhylomeDBi | P51692 |
TreeFami | TF318648 |
Family and domain databases
CDDi | cd10420, SH2_STAT5b, 1 hit |
Gene3Di | 1.10.532.10, 1 hit 2.60.40.630, 1 hit 3.30.505.10, 1 hit |
InterProi | View protein in InterPro IPR008967, p53-like_TF_DNA-bd IPR000980, SH2 IPR036860, SH2_dom_sf IPR001217, STAT IPR035858, STAT5a/5b IPR035886, STAT5b_SH2 IPR036535, STAT_N_sf IPR013800, STAT_TF_alpha IPR015988, STAT_TF_coiled-coil IPR013801, STAT_TF_DNA-bd IPR012345, STAT_TF_DNA-bd_N IPR013799, STAT_TF_prot_interaction |
PANTHERi | PTHR11801, PTHR11801, 1 hit PTHR11801:SF47, PTHR11801:SF47, 1 hit |
Pfami | View protein in Pfam PF00017, SH2, 1 hit PF01017, STAT_alpha, 1 hit PF02864, STAT_bind, 1 hit PF02865, STAT_int, 1 hit |
SMARTi | View protein in SMART SM00252, SH2, 1 hit SM00964, STAT_int, 1 hit |
SUPFAMi | SSF47655, SSF47655, 1 hit SSF48092, SSF48092, 1 hit SSF49417, SSF49417, 1 hit SSF55550, SSF55550, 1 hit |
PROSITEi | View protein in PROSITE PS50001, SH2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
P51692-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAVWIQAQQL QGEALHQMQA LYGQHFPIEV RHYLSQWIES QAWDSVDLDN
60 70 80 90 100
PQENIKATQL LEGLVQELQK KAEHQVGEDG FLLKIKLGHY ATQLQNTYDR
110 120 130 140 150
CPMELVRCIR HILYNEQRLV REANNGSSPA GSLADAMSQK HLQINQTFEE
160 170 180 190 200
LRLVTQDTEN ELKKLQQTQE YFIIQYQESL RIQAQFGPLA QLSPQERLSR
210 220 230 240 250
ETALQQKQVS LEAWLQREAQ TLQQYRVELA EKHQKTLQLL RKQQTIILDD
260 270 280 290 300
ELIQWKRRQQ LAGNGGPPEG SLDVLQSWCE KLAEIIWQNR QQIRRAEHLC
310 320 330 340 350
QQLPIPGPVE EMLAEVNATI TDIISALVTS TFIIEKQPPQ VLKTQTKFAA
360 370 380 390 400
TVRLLVGGKL NVHMNPPQVK ATIISEQQAK SLLKNENTRN DYSGEILNNC
410 420 430 440 450
CVMEYHQATG TLSAHFRNMS LKRIKRSDRR GAESVTEEKF TILFESQFSV
460 470 480 490 500
GGNELVFQVK TLSLPVVVIV HGSQDNNATA TVLWDNAFAE PGRVPFAVPD
510 520 530 540 550
KVLWPQLCEA LNMKFKAEVQ SNRGLTKENL VFLAQKLFNN SSSHLEDYSG
560 570 580 590 600
LSVSWSQFNR ENLPGRNYTF WQWFDGVMEV LKKHLKPHWN DGAILGFVNK
610 620 630 640 650
QQAHDLLINK PDGTFLLRFS DSEIGGITIA WKFDSQERMF WNLMPFTTRD
660 670 680 690 700
FSIRSLADRL GDLNYLIYVF PDRPKDEVYS KYYTPVPCES ATAKAVDGYV
710 720 730 740 750
KPQIKQVVPE FVNASADAGG GSATYMDQAP SPAVCPQAHY NMYPQNPDSV
760 770 780
LDTDGDFDLE DTMDVARRVE ELLGRPMDSQ WIPHAQS
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketC9J4I3 | C9J4I3_HUMAN | Signal transducer and activator of ... | STAT5B | 156 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 230 | A → P in AAC50491 (Ref. 2) Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_052074 | 130 | A → V. Corresponds to variant dbSNP:rs2277619EnsemblClinVar. | 1 | |
Natural variantiVAR_018728 | 630 | A → P in GHII; affects activation by growth hormone or interferon-gamma. 1 PublicationCorresponds to variant dbSNP:rs121908501EnsemblClinVar. | 1 | |
Natural variantiVAR_067368 | 646 | F → S in GHII; transcriptionally inactive. 1 Publication | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U48730 mRNA Translation: AAC50485.2 U47686 mRNA Translation: AAC50491.1 AJ412888 , AJ412889, AJ412890, AJ412891, AJ412892, AJ412893, AJ412894, AJ412895, AJ412896, AJ412897, AJ412898, AJ412899 Genomic DNA Translation: CAD19638.1 BC065227 mRNA Translation: AAH65227.1 |
CCDSi | CCDS11423.1 |
RefSeqi | NP_036580.2, NM_012448.3 |
Genome annotation databases
Ensembli | ENST00000293328; ENSP00000293328; ENSG00000173757 |
GeneIDi | 6777 |
KEGGi | hsa:6777 |
UCSCi | uc002hzh.4, human |
Keywords - Coding sequence diversityi
PolymorphismSimilar proteinsi
Cross-referencesi
Web resourcesi
STAT5Bbase STAT5B mutation db |
Wikipedia STAT5 entry |
Atlas of Genetics and Cytogenetics in Oncology and Haematology |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U48730 mRNA Translation: AAC50485.2 U47686 mRNA Translation: AAC50491.1 AJ412888 , AJ412889, AJ412890, AJ412891, AJ412892, AJ412893, AJ412894, AJ412895, AJ412896, AJ412897, AJ412898, AJ412899 Genomic DNA Translation: CAD19638.1 BC065227 mRNA Translation: AAH65227.1 |
CCDSi | CCDS11423.1 |
RefSeqi | NP_036580.2, NM_012448.3 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
6MBW | X-ray | 3.29 | A/B | 136-703 | [»] | |
6MBZ | X-ray | 3.21 | A/B | 136-703 | [»] | |
SMRi | P51692 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 112654, 76 interactors |
CORUMi | P51692 |
IntActi | P51692, 117 interactors |
MINTi | P51692 |
STRINGi | 9606.ENSP00000293328 |
Chemistry databases
BindingDBi | P51692 |
ChEMBLi | CHEMBL5817 |
DrugBanki | DB01254, Dasatinib |
PTM databases
iPTMneti | P51692 |
PhosphoSitePlusi | P51692 |
Polymorphism and mutation databases
BioMutai | STAT5B |
DMDMi | 41019536 |
Proteomic databases
CPTACi | CPTAC-1638 |
EPDi | P51692 |
jPOSTi | P51692 |
MassIVEi | P51692 |
MaxQBi | P51692 |
PaxDbi | P51692 |
PeptideAtlasi | P51692 |
PRIDEi | P51692 |
ProteomicsDBi | 56378 |
Protocols and materials databases
Antibodypediai | 3804, 887 antibodies |
DNASUi | 6777 |
Genome annotation databases
Ensembli | ENST00000293328; ENSP00000293328; ENSG00000173757 |
GeneIDi | 6777 |
KEGGi | hsa:6777 |
UCSCi | uc002hzh.4, human |
Organism-specific databases
CTDi | 6777 |
DisGeNETi | 6777 |
EuPathDBi | HostDB:ENSG00000173757.9 |
GeneCardsi | STAT5B |
HGNCi | HGNC:11367, STAT5B |
HPAi | ENSG00000173757, Low tissue specificity |
MalaCardsi | STAT5B |
MIMi | 245590, phenotype 604260, gene |
neXtProti | NX_P51692 |
OpenTargetsi | ENSG00000173757 |
Orphaneti | 520, Acute promyelocytic leukemia 220465, Laron syndrome with immunodeficiency |
PharmGKBi | PA36186 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG3667, Eukaryota |
GeneTreei | ENSGT00990000203570 |
HOGENOMi | CLU_014189_2_2_1 |
InParanoidi | P51692 |
OMAi | IWLNRQQ |
OrthoDBi | 327469at2759 |
PhylomeDBi | P51692 |
TreeFami | TF318648 |
Enzyme and pathway databases
PathwayCommonsi | P51692 |
Reactomei | R-HSA-1170546, Prolactin receptor signaling R-HSA-1266695, Interleukin-7 signaling R-HSA-1433557, Signaling by SCF-KIT R-HSA-1839117, Signaling by cytosolic FGFR1 fusion mutants R-HSA-186763, Downstream signal transduction R-HSA-2586552, Signaling by Leptin R-HSA-512988, Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-8854691, Interleukin-20 family signaling R-HSA-8983432, Interleukin-15 signaling R-HSA-8985947, Interleukin-9 signaling R-HSA-9020558, Interleukin-2 signaling R-HSA-9020958, Interleukin-21 signaling R-HSA-9027283, Erythropoietin activates STAT5 R-HSA-9645135, STAT5 Activation R-HSA-9670439, Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-982772, Growth hormone receptor signaling |
SignaLinki | P51692 |
SIGNORi | P51692 |
Miscellaneous databases
BioGRID-ORCSi | 6777, 27 hits in 866 CRISPR screens |
ChiTaRSi | STAT5B, human |
GeneWikii | STAT5B |
GenomeRNAii | 6777 |
Pharosi | P51692, Tchem |
PROi | PR:P51692 |
RNActi | P51692, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000173757, Expressed in blood and 247 other tissues |
ExpressionAtlasi | P51692, baseline and differential |
Genevisiblei | P51692, HS |
Family and domain databases
CDDi | cd10420, SH2_STAT5b, 1 hit |
Gene3Di | 1.10.532.10, 1 hit 2.60.40.630, 1 hit 3.30.505.10, 1 hit |
InterProi | View protein in InterPro IPR008967, p53-like_TF_DNA-bd IPR000980, SH2 IPR036860, SH2_dom_sf IPR001217, STAT IPR035858, STAT5a/5b IPR035886, STAT5b_SH2 IPR036535, STAT_N_sf IPR013800, STAT_TF_alpha IPR015988, STAT_TF_coiled-coil IPR013801, STAT_TF_DNA-bd IPR012345, STAT_TF_DNA-bd_N IPR013799, STAT_TF_prot_interaction |
PANTHERi | PTHR11801, PTHR11801, 1 hit PTHR11801:SF47, PTHR11801:SF47, 1 hit |
Pfami | View protein in Pfam PF00017, SH2, 1 hit PF01017, STAT_alpha, 1 hit PF02864, STAT_bind, 1 hit PF02865, STAT_int, 1 hit |
SMARTi | View protein in SMART SM00252, SH2, 1 hit SM00964, STAT_int, 1 hit |
SUPFAMi | SSF47655, SSF47655, 1 hit SSF48092, SSF48092, 1 hit SSF49417, SSF49417, 1 hit SSF55550, SSF55550, 1 hit |
PROSITEi | View protein in PROSITE PS50001, SH2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | STA5B_HUMAN | |
Accessioni | P51692Primary (citable) accession number: P51692 Secondary accession number(s): Q8WWS8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1996 |
Last sequence update: | January 16, 2004 | |
Last modified: | December 2, 2020 | |
This is version 208 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Human chromosome 17
Human chromosome 17: entries, gene names and cross-references to MIM - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations