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Protein

N-acylglucosamine 2-epimerase

Gene

RENBP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine. Binds to renin forming a protein complex called high molecular weight (HMW) renin and inhibits renin activity. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded.1 Publication

Caution

It is uncertain whether Met-1 or Met-11 is the initiator.Curated

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: N-acetylneuraminate degradation

This protein is involved in the pathway N-acetylneuraminate degradation, which is part of Amino-sugar metabolism.1 Publication
View all proteins of this organism that are known to be involved in the pathway N-acetylneuraminate degradation and in Amino-sugar metabolism.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ATP binding Source: Ensembl
  • endopeptidase inhibitor activity Source: ProtInc
  • N-acylglucosamine 2-epimerase activity Source: UniProtKB
  • peptidase inhibitor activity Source: GO_Central
  • protein homodimerization activity Source: Ensembl

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIsomerase

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-446210 Synthesis of UDP-N-acetyl-glucosamine

SABIO-RK: Biochemical Reaction Kinetics Database

More...
SABIO-RKi
P51606

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00629

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
N-acylglucosamine 2-epimerase (EC:5.1.3.8)
Short name:
AGE
Alternative name(s):
GlcNAc 2-epimerase
N-acetyl-D-glucosamine 2-epimerase
Renin-binding protein
Short name:
RnBP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RENBP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000102032.12

Human Gene Nomenclature Database

More...
HGNCi
HGNC:9959 RENBP

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
312420 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P51606

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
5973

Open Targets

More...
OpenTargetsi
ENSG00000102032

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34325

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB00141 N-Acetyl-D-glucosamine

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RENBP

Domain mapping of disease mutations (DMDM)

More...
DMDMi
294862458

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002089491 – 427N-acylglucosamine 2-epimeraseAdd BLAST427

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P51606

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P51606

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P51606

PeptideAtlas

More...
PeptideAtlasi
P51606

PRoteomics IDEntifications database

More...
PRIDEi
P51606

ProteomicsDB human proteome resource

More...
ProteomicsDBi
56342
56343 [P51606-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P51606

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P51606

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000102032 Expressed in 106 organ(s), highest expression level in spleen

CleanEx database of gene expression profiles

More...
CleanExi
HS_RENBP

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P51606 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P51606 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA000428
HPA000522

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.1 Publication

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
111905, 2 interactors

Protein interaction database and analysis system

More...
IntActi
P51606, 3 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000377303

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P51606

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P51606

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni195 – 216Leucine-zipperAdd BLAST22

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IE08 Eukaryota
COG2942 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000013740

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000252296

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG054048

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P51606

KEGG Orthology (KO)

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KOi
K01787

Identification of Orthologs from Complete Genome Data

More...
OMAi
HDMKFWW

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0EO8

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P51606

TreeFam database of animal gene trees

More...
TreeFami
TF329027

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00249 AGE, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.50.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008928 6-hairpin_glycosidase_sf
IPR012341 6hp_glycosidase-like_sf
IPR034116 AGE_dom

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48208 SSF48208, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P51606-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSKGLPARQD MEKERETLQA WKERVGQELD RVVAFWMEHS HDQEHGGFFT
60 70 80 90 100
CLGREGRVYD DLKYVWLQGR QVWMYCRLYR TFERFRHAQL LDAAKAGGEF
110 120 130 140 150
LLRYARVAPP GKKCAFVLTR DGRPVKVQRT IFSECFYTMA MNELWRATGE
160 170 180 190 200
VRYQTEAVEM MDQIVHWVQE DASGLGRPQL QGAPAAEPMA VPMMLLNLVE
210 220 230 240 250
QLGEADEELA GKYAELGDWC ARRILQHVQR DGQAVLENVS EGGKELPGCL
260 270 280 290 300
GRQQNPGHTL EAGWFLLRHC IRKGDPELRA HVIDKFLLLP FHSGWDPDHG
310 320 330 340 350
GLFYFQDADN FCPTQLEWAM KLWWPHSEAM IAFLMGYSDS GDPVLLRLFY
360 370 380 390 400
QVAEYTFRQF RDPEYGEWFG YLSREGKVAL SIKGGPFKGC FHVPRCLAMC
410 420
EEMLGALLSR PAPAPSPAPT PACRGAE
Length:427
Mass (Da):48,831
Last modified:April 20, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i40D5C485C30BE009
GO
Isoform 2 (identifier: P51606-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     230-254: RDGQAVLENVSEGGKELPGCLGRQQ → ATRWKPAGFCSVIAFGKATPNFEPT
     255-427: Missing.

Show »
Length:254
Mass (Da):29,270
Checksum:i9CB7FE6EED3368F7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A6NKZ2A6NKZ2_HUMAN
N-acylglucosamine 2-epimerase
RENBP
413Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C2G7H7C2G7_HUMAN
N-acylglucosamine 2-epimerase
RENBP
116Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C1A7H7C1A7_HUMAN
N-acylglucosamine 2-epimerase
RENBP
159Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C317H7C317_HUMAN
N-acylglucosamine 2-epimerase
RENBP
125Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WE83F8WE83_HUMAN
N-acylglucosamine 2-epimerase
RENBP
60Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH15558 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAA01082 differs from that shown. Contaminating sequence.Curated
The sequence BAA01082 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti236L → P in AAH15558 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_029339169Q → R. Corresponds to variant dbSNP:rs2229241Ensembl.1
Natural variantiVAR_049182284D → G. Corresponds to variant dbSNP:rs2269371Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_039022230 – 254RDGQA…LGRQQ → ATRWKPAGFCSVIAFGKATP NFEPT in isoform 2. 1 PublicationAdd BLAST25
Alternative sequenceiVSP_039023255 – 427Missing in isoform 2. 1 PublicationAdd BLAST173

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK298125 mRNA Translation: BAG60405.1
U52112 Genomic DNA No translation available.
BC015558 mRNA Translation: AAH15558.1 Different initiation.
D10232 mRNA Translation: BAA01082.1 Sequence problems.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS14738.2 [P51606-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
JX0188

NCBI Reference Sequences

More...
RefSeqi
NP_002901.2, NM_002910.5 [P51606-1]
XP_016885187.1, XM_017029698.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.158331

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000393700; ENSP00000377303; ENSG00000102032 [P51606-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
5973

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:5973

UCSC genome browser

More...
UCSCi
uc004fjo.3 human [P51606-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK298125 mRNA Translation: BAG60405.1
U52112 Genomic DNA No translation available.
BC015558 mRNA Translation: AAH15558.1 Different initiation.
D10232 mRNA Translation: BAA01082.1 Sequence problems.
CCDSiCCDS14738.2 [P51606-1]
PIRiJX0188
RefSeqiNP_002901.2, NM_002910.5 [P51606-1]
XP_016885187.1, XM_017029698.1
UniGeneiHs.158331

3D structure databases

ProteinModelPortaliP51606
SMRiP51606
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi111905, 2 interactors
IntActiP51606, 3 interactors
STRINGi9606.ENSP00000377303

Chemistry databases

DrugBankiDB00141 N-Acetyl-D-glucosamine

PTM databases

iPTMnetiP51606
PhosphoSitePlusiP51606

Polymorphism and mutation databases

BioMutaiRENBP
DMDMi294862458

Proteomic databases

EPDiP51606
MaxQBiP51606
PaxDbiP51606
PeptideAtlasiP51606
PRIDEiP51606
ProteomicsDBi56342
56343 [P51606-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
5973
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000393700; ENSP00000377303; ENSG00000102032 [P51606-1]
GeneIDi5973
KEGGihsa:5973
UCSCiuc004fjo.3 human [P51606-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
5973
DisGeNETi5973
EuPathDBiHostDB:ENSG00000102032.12

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RENBP

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0203300
HGNCiHGNC:9959 RENBP
HPAiHPA000428
HPA000522
MIMi312420 gene
neXtProtiNX_P51606
OpenTargetsiENSG00000102032
PharmGKBiPA34325

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IE08 Eukaryota
COG2942 LUCA
GeneTreeiENSGT00390000013740
HOGENOMiHOG000252296
HOVERGENiHBG054048
InParanoidiP51606
KOiK01787
OMAiHDMKFWW
OrthoDBiEOG091G0EO8
PhylomeDBiP51606
TreeFamiTF329027

Enzyme and pathway databases

UniPathwayi
UPA00629

ReactomeiR-HSA-446210 Synthesis of UDP-N-acetyl-glucosamine
SABIO-RKiP51606

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
RENBP human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
RENBP

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
5973

Protein Ontology

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PROi
PR:P51606

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000102032 Expressed in 106 organ(s), highest expression level in spleen
CleanExiHS_RENBP
ExpressionAtlasiP51606 baseline and differential
GenevisibleiP51606 HS

Family and domain databases

CDDicd00249 AGE, 1 hit
Gene3Di1.50.10.10, 1 hit
InterProiView protein in InterPro
IPR008928 6-hairpin_glycosidase_sf
IPR012341 6hp_glycosidase-like_sf
IPR034116 AGE_dom
SUPFAMiSSF48208 SSF48208, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRENBP_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P51606
Secondary accession number(s): B4DNZ3, Q96BI6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: April 20, 2010
Last modified: December 5, 2018
This is version 158 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  6. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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