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Entry version 171 (11 Dec 2019)
Sequence version 3 (13 Jul 2010)
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Protein

Zinc finger protein 83

Gene

ZNF83

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri93 – 115C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri121 – 143C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri149 – 171C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri177 – 199C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri205 – 227C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri233 – 255C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri261 – 283C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri289 – 311C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri317 – 339C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri345 – 367C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri373 – 395C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri401 – 423C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri429 – 451C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri457 – 479C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri485 – 507C2H2-type 15PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 83
Alternative name(s):
Zinc finger protein 816B
Zinc finger protein HPF1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF83
Synonyms:ZNF816B
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000167766.18

Human Gene Nomenclature Database

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HGNCi
HGNC:13158 ZNF83

Online Mendelian Inheritance in Man (OMIM)

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MIMi
194558 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P51522

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000167766

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37731

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P51522 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF83

Domain mapping of disease mutations (DMDM)

More...
DMDMi
300669707

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000473961 – 516Zinc finger protein 83Add BLAST516

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
P51522

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
P51522

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
P51522

PeptideAtlas

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PeptideAtlasi
P51522

PRoteomics IDEntifications database

More...
PRIDEi
P51522

ProteomicsDB: a multi-organism proteome resource

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ProteomicsDBi
56319 [P51522-1]
56320 [P51522-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P51522

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
P51522

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000167766 Expressed in 221 organ(s), highest expression level in right uterine tube

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
P51522 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
P51522 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA025970

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
120886, 3 interactors

Protein interaction database and analysis system

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IntActi
P51522, 5 interactors

Molecular INTeraction database

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MINTi
P51522

STRING: functional protein association networks

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STRINGi
9606.ENSP00000472619

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

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RNActi
P51522 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P51522

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri93 – 115C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri121 – 143C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri149 – 171C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri177 – 199C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri205 – 227C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri233 – 255C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri261 – 283C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri289 – 311C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri317 – 339C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri345 – 367C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri373 – 395C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri401 – 423C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri429 – 451C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri457 – 479C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri485 – 507C2H2-type 15PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163013

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234617

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P51522

KEGG Orthology (KO)

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KOi
K09228

Identification of Orthologs from Complete Genome Data

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OMAi
NSYLAYH

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P51522

TreeFam database of animal gene trees

More...
TreeFami
TF341892

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096 zf-C2H2, 14 hits

Simple Modular Architecture Research Tool; a protein domain database

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SMARTi
View protein in SMART
SM00355 ZnF_C2H2, 15 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667 SSF57667, 8 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 14 hits
PS50157 ZINC_FINGER_C2H2_2, 15 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 8 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P51522-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MHGRKDDAQK QPVKNQLGLN PQSHLPELQL FQAEGKIYKY DHMEKSVNSS
60 70 80 90 100
SLVSPPQRIS STVKTHISHT YECNFVDSLF TQKEKANIGT EHYKCSERGK
110 120 130 140 150
AFHQGLHFTI HQIIHTKETQ FKCDICGKIF NKKSNLASHQ RIHTGEKPYK
160 170 180 190 200
CNECGKVFHN MSHLAQHRRI HTGEKPYKCN ECGKVFNQIS HLAQHQRIHT
210 220 230 240 250
GEKPYKCNEC GKVFHQISHL AQHRTIHTGE KPYECNKCGK VFSRNSYLVQ
260 270 280 290 300
HLIIHTGEKP YRCNVCGKVF HHISHLAQHQ RIHTGEKPYK CNECGKVFSH
310 320 330 340 350
KSSLVNHWRI HTGEKPYKCN ECGKVFSHKS SLVNHWRIHT GEKPYKCNEC
360 370 380 390 400
GKVFSRNSYL AQHLIIHAGE KPYKCDECDK AFSQNSHLVQ HHRIHTGEKP
410 420 430 440 450
YKCDECGKVF SQNSYLAYHW RIHTGEKAYK CNECGKVFGL NSSLAHHRKI
460 470 480 490 500
HTGEKPFKCN ECGKAFSMRS SLTNHHAIHT GEKHFKCNEC GKLFRDNSYL
510
VRHQRFHAGK KSNTCN
Length:516
Mass (Da):59,710
Last modified:July 13, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA6CA428CFAEA5D69
GO
Isoform 2 (identifier: P51522-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     271-298: Missing.

Show »
Length:488
Mass (Da):56,429
Checksum:i02D19C75A1677C48
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0R099M0R099_HUMAN
Zinc finger protein 83
ZNF83
53Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R0P3M0R0P3_HUMAN
Zinc finger protein 83
ZNF83
125Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R183M0R183_HUMAN
Zinc finger protein 83
ZNF83
71Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R1T0M0R1T0_HUMAN
Zinc finger protein 83
ZNF83
55Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R3A5M0R3A5_HUMAN
Zinc finger protein 83
ZNF83
92Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R287M0R287_HUMAN
Zinc finger protein 83
ZNF83
125Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
L0R8M2L0R8M2_HUMAN
Alternative protein ZNF83
ZNF83
105Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QXM0M0QXM0_HUMAN
Zinc finger protein 83
ZNF83
30Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti89 – 91GTE → MDR in AAG41760 (PubMed:2505992).Curated3
Sequence conflicti108 – 109FT → LP in AAG41760 (PubMed:2505992).Curated2

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05820670T → I. Corresponds to variant dbSNP:rs3786490Ensembl.1
Natural variantiVAR_05820796S → N3 PublicationsCorresponds to variant dbSNP:rs1056185Ensembl.1
Natural variantiVAR_058208119T → M. Corresponds to variant dbSNP:rs329940Ensembl.1
Natural variantiVAR_058209392H → R1 PublicationCorresponds to variant dbSNP:rs11545619Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_037663271 – 298Missing in isoform 2. 2 PublicationsAdd BLAST28

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK289399 mRNA Translation: BAF82088.1
AC022150 Genomic DNA No translation available.
BC050407 mRNA Translation: AAH50407.1
BC032867 mRNA Translation: AAH32867.1
M27877 mRNA Translation: AAG41760.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS12854.1 [P51522-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
A32891

NCBI Reference Sequences

More...
RefSeqi
NP_001099019.1, NM_001105549.1 [P51522-1]
NP_001099020.1, NM_001105550.1 [P51522-1]
NP_001099021.1, NM_001105551.1 [P51522-1]
NP_001099022.1, NM_001105552.1 [P51522-1]
NP_001264874.1, NM_001277945.1 [P51522-1]
NP_001264875.1, NM_001277946.1 [P51522-1]
NP_001264876.1, NM_001277947.1 [P51522-1]
NP_001264877.1, NM_001277948.1 [P51522-1]
NP_001264878.1, NM_001277949.1 [P51522-1]
NP_001264880.1, NM_001277951.1 [P51522-1]
NP_001264881.1, NM_001277952.1 [P51522-1]
NP_001334944.1, NM_001348015.1 [P51522-1]
NP_001334945.1, NM_001348016.1 [P51522-1]
NP_001334946.1, NM_001348017.1 [P51522-1]
NP_001334947.1, NM_001348018.1 [P51522-1]
NP_001334948.1, NM_001348019.1 [P51522-1]
NP_060770.3, NM_018300.3 [P51522-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000301096; ENSP00000301096; ENSG00000167766 [P51522-1]
ENST00000536937; ENSP00000445993; ENSG00000167766 [P51522-1]
ENST00000541777; ENSP00000439681; ENSG00000167766 [P51522-1]
ENST00000545872; ENSP00000440713; ENSG00000167766 [P51522-1]
ENST00000597597; ENSP00000472619; ENSG00000167766 [P51522-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
55769

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:55769

UCSC genome browser

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UCSCi
uc002pzu.5 human [P51522-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK289399 mRNA Translation: BAF82088.1
AC022150 Genomic DNA No translation available.
BC050407 mRNA Translation: AAH50407.1
BC032867 mRNA Translation: AAH32867.1
M27877 mRNA Translation: AAG41760.1
CCDSiCCDS12854.1 [P51522-1]
PIRiA32891
RefSeqiNP_001099019.1, NM_001105549.1 [P51522-1]
NP_001099020.1, NM_001105550.1 [P51522-1]
NP_001099021.1, NM_001105551.1 [P51522-1]
NP_001099022.1, NM_001105552.1 [P51522-1]
NP_001264874.1, NM_001277945.1 [P51522-1]
NP_001264875.1, NM_001277946.1 [P51522-1]
NP_001264876.1, NM_001277947.1 [P51522-1]
NP_001264877.1, NM_001277948.1 [P51522-1]
NP_001264878.1, NM_001277949.1 [P51522-1]
NP_001264880.1, NM_001277951.1 [P51522-1]
NP_001264881.1, NM_001277952.1 [P51522-1]
NP_001334944.1, NM_001348015.1 [P51522-1]
NP_001334945.1, NM_001348016.1 [P51522-1]
NP_001334946.1, NM_001348017.1 [P51522-1]
NP_001334947.1, NM_001348018.1 [P51522-1]
NP_001334948.1, NM_001348019.1 [P51522-1]
NP_060770.3, NM_018300.3 [P51522-1]

3D structure databases

SMRiP51522
ModBaseiSearch...

Protein-protein interaction databases

BioGridi120886, 3 interactors
IntActiP51522, 5 interactors
MINTiP51522
STRINGi9606.ENSP00000472619

PTM databases

iPTMnetiP51522
PhosphoSitePlusiP51522

Polymorphism and mutation databases

BioMutaiZNF83
DMDMi300669707

Proteomic databases

jPOSTiP51522
MassIVEiP51522
PaxDbiP51522
PeptideAtlasiP51522
PRIDEiP51522
ProteomicsDBi56319 [P51522-1]
56320 [P51522-2]

Genome annotation databases

EnsembliENST00000301096; ENSP00000301096; ENSG00000167766 [P51522-1]
ENST00000536937; ENSP00000445993; ENSG00000167766 [P51522-1]
ENST00000541777; ENSP00000439681; ENSG00000167766 [P51522-1]
ENST00000545872; ENSP00000440713; ENSG00000167766 [P51522-1]
ENST00000597597; ENSP00000472619; ENSG00000167766 [P51522-1]
GeneIDi55769
KEGGihsa:55769
UCSCiuc002pzu.5 human [P51522-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55769
EuPathDBiHostDB:ENSG00000167766.18

GeneCards: human genes, protein and diseases

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GeneCardsi
ZNF83
HGNCiHGNC:13158 ZNF83
HPAiHPA025970
MIMi194558 gene
neXtProtiNX_P51522
OpenTargetsiENSG00000167766
PharmGKBiPA37731

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000163013
HOGENOMiHOG000234617
InParanoidiP51522
KOiK09228
OMAiNSYLAYH
OrthoDBi1318335at2759
PhylomeDBiP51522
TreeFamiTF341892

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ZNF83 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
ZNF83

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
55769
PharosiP51522 Tdark

Protein Ontology

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PROi
PR:P51522
RNActiP51522 protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSG00000167766 Expressed in 221 organ(s), highest expression level in right uterine tube
ExpressionAtlasiP51522 baseline and differential
GenevisibleiP51522 HS

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 14 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 15 hits
SUPFAMiSSF57667 SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 14 hits
PS50157 ZINC_FINGER_C2H2_2, 15 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZNF83_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P51522
Secondary accession number(s): A8MT75, Q3ZCX0, Q6PI08
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: July 13, 2010
Last modified: December 11, 2019
This is version 171 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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