UniProtKB - P51335 (MOEB_PORPU)
Protein
Probable molybdopterin-synthase adenylyltransferase
Gene
moeB
Organism
Porphyra purpurea (Red seaweed) (Ulva purpurea)
Status
Functioni
Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD.By similarity
Catalytic activityi
- [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + ATP + H+ = [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly-AMP + diphosphateEC:2.7.7.80
: molybdopterin biosynthesis Pathwayi
This protein is involved in the pathway molybdopterin biosynthesis, which is part of Cofactor biosynthesis.View all proteins of this organism that are known to be involved in the pathway molybdopterin biosynthesis and in Cofactor biosynthesis.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 48 | ATP; via amide nitrogenBy similarity | 1 | |
Binding sitei | 69 | ATPBy similarity | 1 | |
Binding sitei | 93 | ATPBy similarity | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 76 – 80 | ATPBy similarity | 5 | |
Nucleotide bindingi | 137 – 138 | ATPBy similarity | 2 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- molybdopterin-synthase adenylyltransferase activity Source: UniProtKB-EC
- ubiquitin-like modifier activating enzyme activity Source: InterPro
GO - Biological processi
- Mo-molybdopterin cofactor biosynthetic process Source: UniProtKB-KW
Keywordsi
Molecular function | Nucleotidyltransferase, Transferase |
Biological process | Molybdenum cofactor biosynthesis |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
UniPathwayi | UPA00344 |
Names & Taxonomyi
Protein namesi | Recommended name: Probable molybdopterin-synthase adenylyltransferase (EC:2.7.7.80)Alternative name(s): MoaD protein adenylase Molybdopterin-converting factor subunit 1 adenylase Sulfur carrier protein MoaD adenylyltransferase |
Gene namesi | Name:moeB |
Encoded oni | Plastid; Chloroplast |
Organismi | Porphyra purpurea (Red seaweed) (Ulva purpurea) |
Taxonomic identifieri | 2787 [NCBI] |
Taxonomic lineagei | Eukaryota › Rhodophyta › Bangiophyceae › Bangiales › Bangiaceae › Porphyra |
Subcellular locationi
Chloroplast
Chloroplast
- chloroplast Source: UniProtKB-SubCell
Keywords - Cellular componenti
Chloroplast, PlastidPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000120574 | 1 – 382 | Probable molybdopterin-synthase adenylyltransferaseAdd BLAST | 382 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 288 – 377 | RhodanesePROSITE-ProRule annotationAdd BLAST | 90 |
Sequence similaritiesi
Belongs to the HesA/MoeB/ThiF family.Curated
Family and domain databases
Gene3Di | 3.40.250.10, 1 hit |
InterProi | View protein in InterPro IPR001763, Rhodanese-like_dom IPR036873, Rhodanese-like_dom_sf IPR000594, ThiF_NAD_FAD-bd IPR035985, Ubiquitin-activating_enz |
Pfami | View protein in Pfam PF00581, Rhodanese, 1 hit PF00899, ThiF, 1 hit |
SMARTi | View protein in SMART SM00450, RHOD, 1 hit |
SUPFAMi | SSF69572, SSF69572, 1 hit |
PROSITEi | View protein in PROSITE PS50206, RHODANESE_3, 1 hit |
i Sequence
Sequence statusi: Complete.
P51335-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLNFRAKCTT YSLEEYTRYS KHLILPQIKL EGQERLKQSS ILCVGAGGLG
60 70 80 90 100
SPALIYLAAS GIGKIGIVDN DIIDISNLQR QILYTVNDIG LSKAYIAKKK
110 120 130 140 150
ILEINPTCNV QIFNTRLQSI NAIEIIRQYD IIIDGTDNFG SRYIISDSCL
160 170 180 190 200
ELNKIHIYGA IFQFEGQVST FNYQGGPKYR DFHNNIETEN NPEDTCSNAG
210 220 230 240 250
VLGLLPGIIG TLQATEAIKI ILGYKSVLSG IILKYNAMTI SFEKFKIIHT
260 270 280 290 300
QFILSQPKKK IKSLLVGNSS YPVQEIDVIE LQNELYRNSF KYIILDVRSK
310 320 330 340 350
EEYEESHLDK AVNLPIKDMK KRYYSDLNLQ DKISFIYCSV DSRSIFAYNF
360 370 380
LRKQEFKVIR VKGGLSSWTN IIGNEKLYVK SC
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U38804 Genomic DNA Translation: AAC08221.1 |
PIRi | S73256 |
RefSeqi | NP_053945.1, NC_000925.1 |
Genome annotation databases
GeneIDi | 809970 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U38804 Genomic DNA Translation: AAC08221.1 |
PIRi | S73256 |
RefSeqi | NP_053945.1, NC_000925.1 |
3D structure databases
SMRi | P51335 |
ModBasei | Search... |
Genome annotation databases
GeneIDi | 809970 |
Enzyme and pathway databases
UniPathwayi | UPA00344 |
Family and domain databases
Gene3Di | 3.40.250.10, 1 hit |
InterProi | View protein in InterPro IPR001763, Rhodanese-like_dom IPR036873, Rhodanese-like_dom_sf IPR000594, ThiF_NAD_FAD-bd IPR035985, Ubiquitin-activating_enz |
Pfami | View protein in Pfam PF00581, Rhodanese, 1 hit PF00899, ThiF, 1 hit |
SMARTi | View protein in SMART SM00450, RHOD, 1 hit |
SUPFAMi | SSF69572, SSF69572, 1 hit |
PROSITEi | View protein in PROSITE PS50206, RHODANESE_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | MOEB_PORPU | |
Accessioni | P51335Primary (citable) accession number: P51335 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1996 |
Last sequence update: | October 1, 1996 | |
Last modified: | December 11, 2019 | |
This is version 80 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) |
Miscellaneousi
Documents
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families