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Protein

Nitrogen regulatory protein P-II

Gene

glnB

Organism
Porphyra purpurea (Red seaweed) (Ulva purpurea)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

P-II indirectly controls the transcription of the glutamine synthetase gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase, so activating the enzyme (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulation
LigandNucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Nitrogen regulatory protein P-II
Gene namesi
Name:glnB
Encoded oniPlastid; Chloroplast
OrganismiPorphyra purpurea (Red seaweed) (Ulva purpurea)
Taxonomic identifieri2787 [NCBI]
Taxonomic lineageiEukaryotaRhodophytaBangiophyceaeBangialesBangiaceaePorphyra

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001397991 – 112Nitrogen regulatory protein P-IIAdd BLAST112

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei51O-UMP-tyrosinePROSITE-ProRule annotation1

Keywords - PTMi

Phosphoprotein

Interactioni

Subunit structurei

Homotrimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP51254
SMRiP51254
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the P(II) protein family.PROSITE-ProRule annotation

Family and domain databases

Gene3Di3.30.70.120, 1 hit
InterProiView protein in InterPro
IPR002187 N-reg_PII
IPR011322 N-reg_PII-like_a/b
IPR015867 N-reg_PII/ATP_PRibTrfase_C
IPR017918 N-reg_PII_CS
IPR002332 N-reg_PII_urydylation_site
PANTHERiPTHR30115 PTHR30115, 1 hit
PfamiView protein in Pfam
PF00543 P-II, 1 hit
PRINTSiPR00340 PIIGLNB
SMARTiView protein in SMART
SM00938 P-II, 1 hit
SUPFAMiSSF54913 SSF54913, 1 hit
PROSITEiView protein in PROSITE
PS00638 PII_GLNB_CTER, 1 hit
PS51343 PII_GLNB_DOM, 1 hit
PS00496 PII_GLNB_UMP, 1 hit

Sequencei

Sequence statusi: Complete.

P51254-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKKIEAIIRP FKLNEVKLAL VKGGIGGMTV VKVSGFGRQK GQTERYKGSE
60 70 80 90 100
YSIDIIDKIK IEIIVSDDKV NSITEIIIKT AKTGEIGDGK IFISDVEQVI
110
RIRTNDLNSA AL
Length:112
Mass (Da):12,320
Last modified:October 1, 1996 - v1
Checksum:i29416AA49FC37A18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38804 Genomic DNA Translation: AAC08140.1
PIRiS73175
RefSeqiNP_053864.1, NC_000925.1

Genome annotation databases

GeneIDi809883

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U38804 Genomic DNA Translation: AAC08140.1
PIRiS73175
RefSeqiNP_053864.1, NC_000925.1

3D structure databases

ProteinModelPortaliP51254
SMRiP51254
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi809883

Family and domain databases

Gene3Di3.30.70.120, 1 hit
InterProiView protein in InterPro
IPR002187 N-reg_PII
IPR011322 N-reg_PII-like_a/b
IPR015867 N-reg_PII/ATP_PRibTrfase_C
IPR017918 N-reg_PII_CS
IPR002332 N-reg_PII_urydylation_site
PANTHERiPTHR30115 PTHR30115, 1 hit
PfamiView protein in Pfam
PF00543 P-II, 1 hit
PRINTSiPR00340 PIIGLNB
SMARTiView protein in SMART
SM00938 P-II, 1 hit
SUPFAMiSSF54913 SSF54913, 1 hit
PROSITEiView protein in PROSITE
PS00638 PII_GLNB_CTER, 1 hit
PS51343 PII_GLNB_DOM, 1 hit
PS00496 PII_GLNB_UMP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiGLNB_PORPU
AccessioniPrimary (citable) accession number: P51254
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: December 20, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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