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UniProtKB - P51109 (DFRA_MEDSA)
Protein
Dihydroflavonol 4-reductase
Gene
DFR1
Organism
Medicago sativa (Alfalfa)
Status
Functioni
Bifunctional enzyme involved in flavonoid metabolism.
By similarityCatalytic activityi
: anthocyanin biosynthesis Pathwayi
This protein is involved in the pathway anthocyanin biosynthesis, which is part of Pigment biosynthesis.View all proteins of this organism that are known to be involved in the pathway anthocyanin biosynthesis and in Pigment biosynthesis.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 27 | NADPBy similarity | 1 | |
Binding sitei | 146 | NADPBy similarity | 1 |
GO - Molecular functioni
- dihydrokaempferol 4-reductase activity Source: UniProtKB-EC
- flavanone 4-reductase activity Source: UniProtKB-EC
GO - Biological processi
- anthocyanin-containing compound biosynthetic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Oxidoreductase |
Biological process | Flavonoid biosynthesis |
Ligand | NADP |
Enzyme and pathway databases
UniPathwayi | UPA00009 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:DFR1 |
Organismi | Medicago sativa (Alfalfa) |
Taxonomic identifieri | 3879 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › fabids › Fabales › Fabaceae › Papilionoideae › 50 kb inversion clade › NPAAA clade › Hologalegina › IRL clade › Trifolieae › Medicago |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000215570 | ‹1 – ›217 | Dihydroflavonol 4-reductaseAdd BLAST | ›217 |
Family & Domainsi
Sequence similaritiesi
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.Curated
Family and domain databases
InterProi | View protein in InterPro IPR001509, Epimerase_deHydtase IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF01370, Epimerase, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit |
i Sequence
Sequence statusi: Fragment.
P51109-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
GSWLVMRLME PGYMVRATVR DPENLKKVSP LLELPGAKSK LSIWKADLGE
60 70 80 90 100
EGSFDEAIKG CTGVFHVATP MDFESKDPEN EMIKPTIKGV LDIMKACLKA
110 120 130 140 150
KTVRRLIYTS SAGTLNVTED QKPLWDESCW SDVEFCRRVK MTGWMYFVSK
160 170 180 190 200
TLAEQEAWKF AKEHKMDVIT IIPPLVVGPF LIPTMPPSLI TALSPITGNE
210
AHYSIIKQGQ YVHLDDL
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | 1 | ||
Non-terminal residuei | 217 | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X80222 mRNA Translation: CAA56508.1 |
PIRi | S61416 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X80222 mRNA Translation: CAA56508.1 |
PIRi | S61416 |
3D structure databases
SMRi | P51109 |
ModBasei | Search... |
Enzyme and pathway databases
UniPathwayi | UPA00009 |
Family and domain databases
InterProi | View protein in InterPro IPR001509, Epimerase_deHydtase IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF01370, Epimerase, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | DFRA_MEDSA | |
Accessioni | P51109Primary (citable) accession number: P51109 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1996 |
Last sequence update: | October 1, 1996 | |
Last modified: | February 23, 2022 | |
This is version 78 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Documents
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families