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UniProtKB - P51108 (DFRA_MAIZE)
Protein
Dihydroflavonol 4-reductase
Gene
A1
Organism
Zea mays (Maize)
Status
Functioni
Bifunctional enzyme involved in flavonoid metabolism.
By similarityCatalytic activityi
: anthocyanin biosynthesis Pathwayi
This protein is involved in the pathway anthocyanin biosynthesis, which is part of Pigment biosynthesis.View all proteins of this organism that are known to be involved in the pathway anthocyanin biosynthesis and in Pigment biosynthesis.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 49 | NADPBy similarity | 1 | |
Binding sitei | 168 | NADPBy similarity | 1 |
GO - Molecular functioni
- dihydrokaempferol 4-reductase activity Source: UniProtKB-EC
- flavanone 4-reductase activity Source: UniProtKB-EC
- oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: GO_Central
GO - Biological processi
- anthocyanin-containing compound biosynthetic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Oxidoreductase |
Biological process | Flavonoid biosynthesis |
Ligand | NADP |
Enzyme and pathway databases
UniPathwayi | UPA00009 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:A1 |
Organismi | Zea mays (Maize) |
Taxonomic identifieri | 4577 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › PACMAD clade › Panicoideae › Andropogonodae › Andropogoneae › Tripsacinae › Zea |
Proteomesi |
|
Organism-specific databases
MaizeGDBi | 13795 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000215569 | 1 – 357 | Dihydroflavonol 4-reductaseAdd BLAST | 357 |
Proteomic databases
PaxDbi | P51108 |
Family & Domainsi
Sequence similaritiesi
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.Curated
Phylogenomic databases
eggNOGi | KOG1502, Eukaryota |
Family and domain databases
InterProi | View protein in InterPro IPR001509, Epimerase_deHydtase IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF01370, Epimerase, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit |
i Sequence
Sequence statusi: Complete.
P51108-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MERGAGASEK GTVLVTGASG FVGSWLVMKL LQAGYTVRAT VRDPANVGKT
60 70 80 90 100
KPLMDLPGAT ERLSIWKADL AEEGSFHDAI RGCTGVFHVA TPMDFLSKDP
110 120 130 140 150
ENEVIKPTVE GMISIMRACK EAGTVRRIVF TSSAGTVNLE ERQRPVYDEE
160 170 180 190 200
SWTDVDFCRR VKMTGWMYFV SKTLAEKAAL AYAAEHGLDL VTIIPTLVVG
210 220 230 240 250
PFISASMPPS LITALALITG NAPHYSILKQ VQLIHLDDLC DAEIFLFENP
260 270 280 290 300
AAAGRYVCSS HDVTIHGLAA MLRDRYPEYD VPQRFPGIQD DLQPVRFSSK
310 320 330 340 350
KLQDLGFTFR YKTLEDMFDA AIRTCQEKGL IPLATAAGGD GFASVRAPGE
TEATIGA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X05068 Genomic DNA Translation: CAA28734.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X05068 Genomic DNA Translation: CAA28734.1 |
3D structure databases
SMRi | P51108 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 4577.GRMZM2G026930_P01 |
Proteomic databases
PaxDbi | P51108 |
Organism-specific databases
MaizeGDBi | 13795 |
Phylogenomic databases
eggNOGi | KOG1502, Eukaryota |
Enzyme and pathway databases
UniPathwayi | UPA00009 |
Gene expression databases
ExpressionAtlasi | P51108, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR001509, Epimerase_deHydtase IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF01370, Epimerase, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | DFRA_MAIZE | |
Accessioni | P51108Primary (citable) accession number: P51108 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1996 |
Last sequence update: | October 1, 1996 | |
Last modified: | February 23, 2022 | |
This is version 100 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families