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Protein

Dihydroflavonol 4-reductase

Gene

A1

Organism
Zea mays (Maize)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Bifunctional enzyme involved in flavonoid metabolism.By similarity

Catalytic activityi

A (2R,3S,4S)-leucoanthocyanidin + NADP+ = a (2R,3R)-dihydroflavonol + NADPH.By similarity
(2S)-flavan-4-ol + NADP+ = (2S)-flavanone + NADPH.By similarity

Pathwayi: anthocyanin biosynthesis

This protein is involved in the pathway anthocyanin biosynthesis, which is part of Pigment biosynthesis.
View all proteins of this organism that are known to be involved in the pathway anthocyanin biosynthesis and in Pigment biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processFlavonoid biosynthesis
LigandNADP

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-18488
UniPathwayi
UPA00009

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydroflavonol 4-reductase (EC:1.1.1.219By similarity)
Short name:
DFR
Alternative name(s):
Dihydrokaempferol 4-reductase
Flavanone 4-reductase (EC:1.1.1.234By similarity)
Short name:
FNR
Gene namesi
Name:A1
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea
Proteomesi
  • UP000007305 Componenti: Unplaced

Organism-specific databases

MaizeGDBi13795

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002155691 – 357Dihydroflavonol 4-reductaseAdd BLAST357

Proteomic databases

PaxDbiP51108
PRIDEiP51108

Expressioni

Gene expression databases

ExpressionAtlasiP51108 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi4577.GRMZM2G026930_P01

Structurei

3D structure databases

ProteinModelPortaliP51108
SMRiP51108
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1502 Eukaryota
COG0451 LUCA
HOGENOMiHOG000167998

Family and domain databases

InterProiView protein in InterPro
IPR001509 Epimerase_deHydtase
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF01370 Epimerase, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit

Sequencei

Sequence statusi: Complete.

P51108-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MERGAGASEK GTVLVTGASG FVGSWLVMKL LQAGYTVRAT VRDPANVGKT
60 70 80 90 100
KPLMDLPGAT ERLSIWKADL AEEGSFHDAI RGCTGVFHVA TPMDFLSKDP
110 120 130 140 150
ENEVIKPTVE GMISIMRACK EAGTVRRIVF TSSAGTVNLE ERQRPVYDEE
160 170 180 190 200
SWTDVDFCRR VKMTGWMYFV SKTLAEKAAL AYAAEHGLDL VTIIPTLVVG
210 220 230 240 250
PFISASMPPS LITALALITG NAPHYSILKQ VQLIHLDDLC DAEIFLFENP
260 270 280 290 300
AAAGRYVCSS HDVTIHGLAA MLRDRYPEYD VPQRFPGIQD DLQPVRFSSK
310 320 330 340 350
KLQDLGFTFR YKTLEDMFDA AIRTCQEKGL IPLATAAGGD GFASVRAPGE

TEATIGA
Length:357
Mass (Da):38,856
Last modified:October 1, 1996 - v1
Checksum:i6892B51E30E52804
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X05068 Genomic DNA Translation: CAA28734.1
UniGeneiZm.95153

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X05068 Genomic DNA Translation: CAA28734.1
UniGeneiZm.95153

3D structure databases

ProteinModelPortaliP51108
SMRiP51108
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4577.GRMZM2G026930_P01

Proteomic databases

PaxDbiP51108
PRIDEiP51108

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MaizeGDBi13795

Phylogenomic databases

eggNOGiKOG1502 Eukaryota
COG0451 LUCA
HOGENOMiHOG000167998

Enzyme and pathway databases

UniPathwayi
UPA00009

BioCyciMetaCyc:MONOMER-18488

Gene expression databases

ExpressionAtlasiP51108 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR001509 Epimerase_deHydtase
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF01370 Epimerase, 1 hit
SUPFAMiSSF51735 SSF51735, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiDFRA_MAIZE
AccessioniPrimary (citable) accession number: P51108
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 7, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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