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Entry version 161 (02 Jun 2021)
Sequence version 2 (27 Sep 2005)
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Protein

E3 ubiquitin-protein ligase msl-2

Gene

msl-2

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

The Msl proteins are essential for elevating transcription of the single X chromosome in the male (X chromosome dosage compensation). Msl-2 is required for translation and/or stability of msl-1 in males. In complex with msl-1, acts as an E3 ubiquitin ligase that promotes ubiquitination of histone H2B.

4 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri41 – 85RING-typePROSITE-ProRule annotationAdd BLAST45

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, Transferase
Biological processUbl conjugation pathway
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-3214847, HATs acetylate histones

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
E3 ubiquitin-protein ligase msl-2 (EC:2.3.2.-)
Alternative name(s):
E3 ubiquitin-protein transferase msl-2Curated
Protein male-specific lethal-2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:msl-2
ORF Names:CG3241
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0005616, msl-2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Chromosome, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000559621 – 773E3 ubiquitin-protein ligase msl-2Add BLAST773

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P50534

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Only produced in males.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0005616, Expressed in central nervous system and 33 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P50534, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P50534, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the male-specific lethal (MSL) histone acetyltransferase complex at least composed of mof, msl-1, msl-2 and msl-3.

4 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
59776, 28 interactors

Protein interaction database and analysis system

More...
IntActi
P50534, 2 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0077259

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1773
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Biological Magnetic Resonance Data Bank

More...
BMRBi
P50534

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P50534

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni460 – 525DisorderedSequence analysisAdd BLAST66
Regioni572 – 616DisorderedSequence analysisAdd BLAST45
Regioni687 – 773DisorderedSequence analysisAdd BLAST87

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili424 – 468Sequence analysisAdd BLAST45

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi460 – 476Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi506 – 523Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi687 – 708Pro residuesSequence analysisAdd BLAST22
Compositional biasi739 – 763Polar residuesSequence analysisAdd BLAST25

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MSL2 family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri41 – 85RING-typePROSITE-ProRule annotationAdd BLAST45

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QPJR, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000016814

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_009669_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P50534

Identification of Orthologs from Complete Genome Data

More...
OMAi
CEGCSDF

Database of Orthologous Groups

More...
OrthoDBi
943810at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P50534

Family and domain databases

Conserved Domains Database

More...
CDDi
cd13122, MSL2_CXC, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037922, MSL2
IPR032049, Msl2-CXC
IPR032043, Msl2_Znf-RING
IPR033467, Tesmin/TSO1-like_CXC
IPR001841, Znf_RING
IPR013083, Znf_RING/FYVE/PHD
IPR017907, Znf_RING_CS

The PANTHER Classification System

More...
PANTHERi
PTHR16048, PTHR16048, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16682, MSL2-CXC, 1 hit
PF16685, zf-RING_10, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01114, CXC, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00518, ZF_RING_1, 1 hit
PS50089, ZF_RING_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P50534-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQTAYLKVT RIAMRSASNL SKRRVEELNS GLGELRQLLS CVVCCQLLVD
60 70 80 90 100
PYSPKGKRCQ HNVCRLCLRG KKHLFPSCTQ CEGCSDFKTY EENRMMAAQL
110 120 130 140 150
LCYKTLCVHL LHSALFGELA GMRPQVAREL VPRIKLPPKT TQEFIREGSN
160 170 180 190 200
ISDTFDIFLP QPDLPFLKDM PTSLPAETPP TSAVTTPELP YDHHLNISDI
210 220 230 240 250
EAEAAATAEQ GHFSPLPLLP TGSRMGMLSH AGQIVIATES SESGFMDQAW
260 270 280 290 300
TDQVDLSGTV SVSKYTNSGN NFAVSYVMPT SATTKFDPQE LQIGQVVQMA
310 320 330 340 350
DSTQLAVLAA VEETVETSTQ LTVLSTTVEE TVETSTQLEV LTSAEEPNEI
360 370 380 390 400
SDQLANLQVE ESDEALVEET VEEAEGTSIP SEVVAEHMEE DQHLDVHTSQ
410 420 430 440 450
SPTQTEMEEA VEEHVATKTQ LGHVQTELQD AESLQKDFED AKAAAEEAKE
460 470 480 490 500
KEKDLHAISA ELQKEDSDEP TLKRKRTRTL KASQAAKIEP VPSEVKTKVQ
510 520 530 540 550
SGKGALRRIR GKDKEEKVKP PKPKCRCGIS GSSNTLTTCR NSRCPCYKSY
560 570 580 590 600
NSCAGCHCVC CKNPHKEDYV ESDEDDDLED FEMPKDVPEP MTQSEEPVVA
610 620 630 640 650
EPRQEENSMA PPDSSAPISL VPLNNLQQSQ HPLVLVQNEK GEYQGFNIFQ
660 670 680 690 700
GSKPLDPVTV GFTIRVQLQH TDGFGSLPQY AYIMPTIDPP NPPAPSLSPP
710 720 730 740 750
PPPAPDREVI EPPAKKFRTS RTRRGRANFS ALDTVDELVS GGSRSNSAAG
760 770
DRSSATDNAH SLFEEIMSGS DDL
Length:773
Mass (Da):84,856
Last modified:September 27, 2005 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i31830142AD64F4D7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A4V038A4V038_DROME
Male-specific lethal 2
msl-2 Dmel\CG3241, km(2)A, kmA, MSL, msl
773Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti280T → N in CAA88358 (PubMed:7796814).Curated1
Sequence conflicti367 – 370Missing (PubMed:7796814).Curated4
Sequence conflicti371 – 373VEE → LKT in AAA75573 (PubMed:7781064).Curated3
Sequence conflicti380P → Q in CAA88358 (PubMed:7796814).Curated1
Sequence conflicti403 – 405TQT → IQA in CAA88358 (PubMed:7796814).Curated3
Sequence conflicti423H → Q in CAA61529 (PubMed:7588059).Curated1
Sequence conflicti429Q → H (PubMed:7796814).Curated1
Sequence conflicti431 – 433AES → EEP (PubMed:7796814).Curated3
Sequence conflicti431 – 433AES → EEP (PubMed:7588059).Curated3
Sequence conflicti439E → V in CAA88358 (PubMed:7796814).Curated1
Sequence conflicti443A → P in CAA88358 (PubMed:7796814).Curated1
Sequence conflicti471T → A in CAA61529 (PubMed:7588059).Curated1
Sequence conflicti591M → L in CAA61529 (PubMed:7588059).Curated1
Sequence conflicti642E → D in CAA88358 (PubMed:7796814).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L42553 Genomic DNA Translation: AAA75573.1
Z48443 Genomic DNA Translation: CAA88358.1
X89241 Genomic DNA Translation: CAA61529.1
AE014134 Genomic DNA Translation: AAF51104.1
AY128426 mRNA Translation: AAM75019.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S55554

NCBI Reference Sequences

More...
RefSeqi
NP_523467.1, NM_078743.5
NP_722907.1, NM_164536.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0077570; FBpp0077259; FBgn0005616
FBtr0077571; FBpp0077260; FBgn0005616

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
33565

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG3241

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42553 Genomic DNA Translation: AAA75573.1
Z48443 Genomic DNA Translation: CAA88358.1
X89241 Genomic DNA Translation: CAA61529.1
AE014134 Genomic DNA Translation: AAF51104.1
AY128426 mRNA Translation: AAM75019.1
PIRiS55554
RefSeqiNP_523467.1, NM_078743.5
NP_722907.1, NM_164536.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2LUANMR-A520-570[»]
4RKGX-ray2.50A/B520-570[»]
4RKHX-ray2.00C/D/E/F520-570[»]
BMRBiP50534
SMRiP50534
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi59776, 28 interactors
IntActiP50534, 2 interactors
STRINGi7227.FBpp0077259

Proteomic databases

PaxDbiP50534

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
33565

Genome annotation databases

EnsemblMetazoaiFBtr0077570; FBpp0077259; FBgn0005616
FBtr0077571; FBpp0077260; FBgn0005616
GeneIDi33565
KEGGidme:Dmel_CG3241

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
33565
FlyBaseiFBgn0005616, msl-2

Phylogenomic databases

eggNOGiENOG502QPJR, Eukaryota
GeneTreeiENSGT00390000016814
HOGENOMiCLU_009669_0_0_1
InParanoidiP50534
OMAiCEGCSDF
OrthoDBi943810at2759
PhylomeDBiP50534

Enzyme and pathway databases

ReactomeiR-DME-3214847, HATs acetylate histones

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
33565, 0 hits in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
33565

Protein Ontology

More...
PROi
PR:P50534

Gene expression databases

BgeeiFBgn0005616, Expressed in central nervous system and 33 other tissues
ExpressionAtlasiP50534, baseline and differential
GenevisibleiP50534, DM

Family and domain databases

CDDicd13122, MSL2_CXC, 1 hit
Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR037922, MSL2
IPR032049, Msl2-CXC
IPR032043, Msl2_Znf-RING
IPR033467, Tesmin/TSO1-like_CXC
IPR001841, Znf_RING
IPR013083, Znf_RING/FYVE/PHD
IPR017907, Znf_RING_CS
PANTHERiPTHR16048, PTHR16048, 1 hit
PfamiView protein in Pfam
PF16682, MSL2-CXC, 1 hit
PF16685, zf-RING_10, 1 hit
SMARTiView protein in SMART
SM01114, CXC, 1 hit
PROSITEiView protein in PROSITE
PS00518, ZF_RING_1, 1 hit
PS50089, ZF_RING_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMSL2_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P50534
Secondary accession number(s): Q9VQR1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: September 27, 2005
Last modified: June 2, 2021
This is version 161 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
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