Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

T-cell antigen CD7

Gene

Cd7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Not yet known.

GO - Biological processi

  • adaptive immune response Source: UniProtKB-KW
  • homeostasis of number of cells within a tissue Source: MGI

Keywordsi

Molecular functionReceptor
Biological processAdaptive immunity, Immunity

Names & Taxonomyi

Protein namesi
Recommended name:
T-cell antigen CD7
Alternative name(s):
CD_antigen: CD7
Gene namesi
Name:Cd7
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:88344 Cd7

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini24 – 150ExtracellularSequence analysisAdd BLAST127
Transmembranei151 – 171HelicalSequence analysisAdd BLAST21
Topological domaini172 – 210CytoplasmicSequence analysisAdd BLAST39

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000001463424 – 210T-cell antigen CD7Add BLAST187

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi42N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi45 ↔ 111PROSITE-ProRule annotation
Glycosylationi86N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi93N-linked (GlcNAc...) asparagineSequence analysis1
Lipidationi168S-palmitoyl cysteineBy similarity1

Keywords - PTMi

Disulfide bond, Glycoprotein, Lipoprotein, Palmitate

Proteomic databases

PaxDbiP50283
PRIDEiP50283

PTM databases

iPTMnetiP50283
PhosphoSitePlusiP50283

Expressioni

Gene expression databases

BgeeiENSMUSG00000025163
CleanExiMM_CD7
ExpressionAtlasiP50283 baseline and differential
GenevisibleiP50283 MM

Interactioni

Subunit structurei

Interacts with SECTM1.1 Publication

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026159

Structurei

3D structure databases

ProteinModelPortaliP50283
SMRiP50283
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 129Ig-likeAdd BLAST106

Keywords - Domaini

Immunoglobulin domain, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IYNZ Eukaryota
ENOG41117EQ LUCA
GeneTreeiENSGT00390000013965
HOGENOMiHOG000285979
HOVERGENiHBG005290
InParanoidiP50283
KOiK06457
OMAiYEDMSHS
OrthoDBiEOG091G0Q1Y
PhylomeDBiP50283
TreeFamiTF338565

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR039090 CD7
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR013106 Ig_V-set
PANTHERiPTHR15343 PTHR15343, 1 hit
PfamiView protein in Pfam
PF07686 V-set, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SM00406 IGv, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P50283-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQQAVLALL LTLAGILPGP LDAQDVHQSP RLTIASEGDS VNITCSTRGH
60 70 80 90 100
LEGILMKKIW PQAYNVIYFE DRQEPTVDRT FSGRINFSGS QKNLTITISS
110 120 130 140 150
LQLADTGDYT CEAVRKVSAR GLFTTVVVKE KSSQEAYRSQ EPLQTSFSFP
160 170 180 190 200
AAIAVGFFFT GLLLGVVCSM LRKIQIKKLC ASGIKESPCV VYEDMSYSNR
210
KTPCIPNQYQ
Length:210
Mass (Da):23,153
Last modified:October 1, 1996 - v1
Checksum:i0EBD496B8302962B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti69F → L in AAB17482 (PubMed:7509775).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D10329 mRNA Translation: BAA01171.1
U23462 Genomic DNA Translation: AAB17482.1
D31956 Genomic DNA Translation: BAA06728.1
CCDSiCCDS25764.1
PIRiI49294
RefSeqiNP_033984.1, NM_009854.2
UniGeneiMm.4100

Genome annotation databases

EnsembliENSMUST00000026159; ENSMUSP00000026159; ENSMUSG00000025163
GeneIDi12516
KEGGimmu:12516
UCSCiuc007mvc.2 mouse

Similar proteinsi

Entry informationi

Entry nameiCD7_MOUSE
AccessioniPrimary (citable) accession number: P50283
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: July 18, 2018
This is version 134 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health