UniProtKB - P50275 (ASE1_YEAST)
Protein
Anaphase spindle elongation protein
Gene
ASE1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Required for anaphase spindle elongation.1 Publication
Miscellaneous
Present with 556 molecules/cell in log phase SD medium.1 Publication
GO - Molecular functioni
- microtubule binding Source: SGD
GO - Biological processi
- microtubule bundle formation Source: SGD
- mitotic spindle elongation Source: SGD
- mitotic spindle organization Source: SGD
- mitotic spindle pole body separation Source: SGD
- septum digestion after cytokinesis Source: SGD
- spindle midzone assembly Source: SGD
Enzyme and pathway databases
BioCyci | YEAST:G3O-33598-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Anaphase spindle elongation protein |
Gene namesi | Name:ASE1 Ordered Locus Names:YOR058C ORF Names:YOR29-09 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:YOR058C |
SGDi | S000005584 ASE1 |
Subcellular locationi
Cytoskeleton
- spindle 1 Publication
Cytoskeleton
- microtubule Source: SGD
- nuclear microtubule Source: SGD
- spindle Source: SGD
- spindle midzone Source: SGD
Nucleus
- nuclear microtubule Source: SGD
Other locations
- cytoplasm Source: SGD
Keywords - Cellular componenti
Cytoplasm, Cytoskeleton, MicrotubulePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000064694 | 1 – 885 | Anaphase spindle elongation proteinAdd BLAST | 885 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 17 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
MaxQBi | P50275 |
PaxDbi | P50275 |
PRIDEi | P50275 |
TopDownProteomicsi | P50275 |
PTM databases
iPTMneti | P50275 |
Interactioni
Subunit structurei
Interacts with CDC48; the interaction is likely to result in CDC5 degradation.1 Publication
GO - Molecular functioni
- microtubule binding Source: SGD
Protein-protein interaction databases
BioGridi | 34456, 275 interactors |
DIPi | DIP-7343N |
IntActi | P50275, 2 interactors |
MINTi | P50275 |
STRINGi | 4932.YOR058C |
Structurei
3D structure databases
ProteinModelPortali | P50275 |
SMRi | P50275 |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the MAP65/ASE1 family.Curated
Phylogenomic databases
GeneTreei | ENSGT00390000009453 |
HOGENOMi | HOG000034091 |
InParanoidi | P50275 |
KOi | K16732 |
OMAi | ECEWLRQ |
Family and domain databases
InterProi | View protein in InterPro IPR007145 MAP65_Ase1_PRC1 |
PANTHERi | PTHR19321 PTHR19321, 1 hit |
i Sequence
Sequence statusi: Complete.
P50275-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
METATSSPLP IKSRRNSENS GSTTVIPHMN PSLATPLTVS TMVNQSNSKE
60 70 80 90 100
FMKLTPVRIR DFGSPLKNVS TNYHFLDSEN GKGNTMDNMY RENFILISKD
110 120 130 140 150
LEKLLENLNV IYQNIGYSNT EIITKEKIIF TTISNSIKQF FEQADEELKR
160 170 180 190 200
LSAENGIEQD ILNNILERIN DPSGIKTIPD LYIRNAILLQ ESKTVPQSPK
210 220 230 240 250
KPLSLLSKKA ALDTAKKFVL GSFLPRLRDY LKSLITLKHL IQSVKENLPG
260 270 280 290 300
LTEADNEAIA EFPELSTLTA YLLQIENGKG DIGLSMKFII DNRKDILKGS
310 320 330 340 350
AFKTINEESV KHMNEVIKIY EEEYERRFKS VLTKKVSISS ICEQLGTPLA
360 370 380 390 400
TLIGEDFEQD LRSYGEEENS TSEIPNFHPV DRERMSKIDI TLEKLQAIHK
410 420 430 440 450
ERADKKRLLM EQCQKLWTRL KISQEYIKTF MRNNSSLSTE SLGRISKEVM
460 470 480 490 500
RLEAMKKKLI KKLISDSWDK IQELWRTLQY SEESRSKFII VFEELRNSAT
510 520 530 540 550
TLQEDELLLE TCENELKRLE EKLTLYKPIL KLISDFESLQ EDQEFLERSS
560 570 580 590 600
KDSSRLLSRN SHKILLTEEK MRKRITRHFP RVINDLRIKL EEADGLFDQP
610 620 630 640 650
FLFKGKPLSE AIDIQQQEIE AKYPRCRVRM QRSKKGKCGA NKENKVIKNT
660 670 680 690 700
FKATESSIRV PIGLNLNDAN ITYKTPSKKT IQGLTKNDLS QENSLARHMQ
710 720 730 740 750
GTTKLSSPNR RATRLLAPTV ISRNSKGNIE RPTLNRNRSS DLSSSPRINH
760 770 780 790 800
THGEHAVKPR QLFPIPLNKV DTKGSHIPQL TKEKALELLK RSTGTTGKEN
810 820 830 840 850
VRSPERKSSL EDYAQKLSSP YKEPEHSIYK LSMSPEGKFQ LNIQQKDIES
860 870 880
GFDDTSMMED ENDKDFITWK NEQVSKLNGF SFTDI
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U20235 Genomic DNA Translation: AAA75026.1 Z74966 Genomic DNA Translation: CAA99251.1 Z70678 Genomic DNA Translation: CAA94543.1 BK006948 Genomic DNA Translation: DAA10837.1 |
PIRi | S59660 |
RefSeqi | NP_116582.1, NM_001183477.1 |
Genome annotation databases
EnsemblFungii | YOR058C_mRNA; YOR058C_mRNA; YOR058C |
GeneIDi | 854223 |
KEGGi | sce:YOR058C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U20235 Genomic DNA Translation: AAA75026.1 Z74966 Genomic DNA Translation: CAA99251.1 Z70678 Genomic DNA Translation: CAA94543.1 BK006948 Genomic DNA Translation: DAA10837.1 |
PIRi | S59660 |
RefSeqi | NP_116582.1, NM_001183477.1 |
3D structure databases
ProteinModelPortali | P50275 |
SMRi | P50275 |
ModBasei | Search... |
MobiDBi | Search... |
Protein-protein interaction databases
BioGridi | 34456, 275 interactors |
DIPi | DIP-7343N |
IntActi | P50275, 2 interactors |
MINTi | P50275 |
STRINGi | 4932.YOR058C |
PTM databases
iPTMneti | P50275 |
Proteomic databases
MaxQBi | P50275 |
PaxDbi | P50275 |
PRIDEi | P50275 |
TopDownProteomicsi | P50275 |
Protocols and materials databases
Structural Biology Knowledgebase | Search... |
Genome annotation databases
EnsemblFungii | YOR058C_mRNA; YOR058C_mRNA; YOR058C |
GeneIDi | 854223 |
KEGGi | sce:YOR058C |
Organism-specific databases
EuPathDBi | FungiDB:YOR058C |
SGDi | S000005584 ASE1 |
Phylogenomic databases
GeneTreei | ENSGT00390000009453 |
HOGENOMi | HOG000034091 |
InParanoidi | P50275 |
KOi | K16732 |
OMAi | ECEWLRQ |
Enzyme and pathway databases
BioCyci | YEAST:G3O-33598-MONOMER |
Miscellaneous databases
PROi | PR:P50275 |
Family and domain databases
InterProi | View protein in InterPro IPR007145 MAP65_Ase1_PRC1 |
PANTHERi | PTHR19321 PTHR19321, 1 hit |
ProtoNeti | Search... |
Entry informationi
Entry namei | ASE1_YEAST | |
Accessioni | P50275Primary (citable) accession number: P50275 Secondary accession number(s): D6W2C1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1996 |
Last sequence update: | October 1, 1996 | |
Last modified: | February 13, 2019 | |
This is version 132 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome XV
Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names