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1 to 25 of 26  Show
  1. 1
    "Characterization of a cDNA clone for human NAD(+)-specific isocitrate dehydrogenase alpha-subunit and structural comparison with its isoenzymes from different species."
    Kim Y.O., Oh I.U., Park H.S., Jeng J., Song B.J., Huh T.L.
    Biochem. J. 308:63-68(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Category: Sequences.
    Tissue: Heart.
    Source: UniProtKB/Swiss-Prot (reviewed).
  2. 2
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Category: Sequences.
    Tissue: Brain cortex.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2471 other entries.

  3. 3
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  4. 4
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Category: Sequences.
    Tissue: Lymph.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50448 other entries.

  5. 5
    Lubec G., Vishwanath V., Chen W.-Q., Sun Y.
    Submitted (DEC-2008) to UniProtKB
    Cited for: PROTEIN SEQUENCE OF 135-146; 179-188 AND 300-316, IDENTIFICATION BY MASS SPECTROMETRY.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  6. 6
    "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
    Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
    Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-343, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3123 other entries.

  7. 7
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 18117 other entries.

  8. 8
    Cited for: CLEAVAGE OF TRANSIT PEPTIDE [LARGE SCALE ANALYSIS] AFTER PHE-27, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 6322 other entries.

  9. 9
    "The beta and gamma subunits play distinct functional roles in the alpha2betagamma heterotetramer of human NAD-dependent isocitrate dehydrogenase."
    Ma T., Peng Y., Huang W., Liu Y., Ding J.
    Sci. Rep. 7:41882-41882(2017) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBUNIT, ACTIVITY REGULATION, BIOPHYSICOCHEMICAL PROPERTIES, COFACTOR, CATALYTIC ACTIVITY, MUTAGENESIS OF TYR-153.
    Category: Function, Pathology & Biotech, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 other entries.

  10. 10
    "Molecular mechanism of the allosteric regulation of the alphagamma heterodimer of human NAD-dependent isocitrate dehydrogenase."
    Ma T., Peng Y., Huang W., Ding J.
    Sci. Rep. 7:40921-40921(2017) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.31 ANGSTROMS) OF 28-366 IN COMPLEX WITH MAGNESIUM AND CITRATE, SUBUNIT, CATALYTIC ACTIVITY, COFACTOR, ACTIVITY REGULATION, MUTAGENESIS OF GLU-152; TYR-153; LYS-169; LYS-200; ASN-202; ASP-208 AND TYR-255.
    Category: Function, Pathology & Biotech, Interaction, Structure.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 other entries.

  11. 11
    "Evaluation by mutagenesis of the importance of 3 arginines in alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase."
    Soundar S., Park J.H., Huh T.L., Colman R.F.
    J. Biol. Chem. 278:52146-52153(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Interaction.
    Annotation: for IDH a normal alpha subunit is required for catalytic activity and alpha-Arg88 likely participates in the isocitrate site whereas the beta and gamma subunits have roles in the nucleotide functions of this allosteric enzyme. [GeneRIF:3419]. Pathway. [Reactome:R-HSA-70962].
    Source: IntAct:P50213, GeneRIF:3419, Reactome:R-HSA-70962.

    This publication is mapped to 7 other entries.

  12. 12
    Category: Interaction.
    Source: IntAct:P50213.

    This publication is cited by 4 and mapped to 512 other entries.

  13. 13
    "Identification of Mn2+-binding aspartates from alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase."
    Soundar S., O'hagan M., Fomulu K.S., Colman R.F.
    J. Biol. Chem. 281:21073-21081(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: active sites of the human NAD-IDH are shared between alpha and gamma subunits and between alpha and beta subunits. [GeneRIF:3419]. Pathway. [Reactome:R-HSA-70962].
    Source: GeneRIF:3419, Reactome:R-HSA-70962.

    This publication is mapped to 15 other entries.

  14. 14
    "Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach."
    Koch H.B., Zhang R., Verdoodt B., Bailey A., Zhang C.D., Yates J.R., Menssen A., Hermeking H.
    Cell Cycle 6:205-217(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:P50213.

    This publication is mapped to 221 other entries.

  15. 15
    "Role of alpha-Asp181, beta-Asp192, and gamma-Asp190 in the distinctive subunits of human NAD-specific isocitrate dehydrogenase."
    Bzymek K.P., Colman R.F.
    Biochemistry 46:5391-5397(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Asp181 is essential for nicotinamide-adenine dinucleotide (NAD)-specific IDH alpha subunit catalysis and may also facilitate the binding of substrates. [GeneRIF:3419]. Pathway. [Reactome:R-HSA-70962].
    Source: GeneRIF:3419, Reactome:R-HSA-70962.

    This publication is mapped to 15 other entries.

  16. 16
    "Defining the human deubiquitinating enzyme interaction landscape."
    Sowa M.E., Bennett E.J., Gygi S.P., Harper J.W.
    Cell 138:389-403(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:P50213.

    This publication is mapped to 1015 other entries.

  17. 17
    "A three-stage genome-wide association study of general cognitive ability: hunting the small effects."
    Davis O.S., Butcher L.M., Docherty S.J., Meaburn E.L., Curtis C.J., Simpson M.A., Schalkwyk L.C., Plomin R.
    Behav. Genet. 40:759-767(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: Observational study and genome-wide association study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:3419.

    This publication is mapped to 102 other entries.

  18. 18
    "Each conserved active site tyr in the three subunits of human isocitrate dehydrogenase has a different function."
    Dange M., Colman R.F.
    J. Biol. Chem. 285:20520-20525(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-70962.

    This publication is mapped to 2 other entries.

  19. 19
    "Network organization of the human autophagy system."
    Behrends C., Sowa M.E., Gygi S.P., Harper J.W.
    Nature 466:68-76(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:P50213.

    This publication is cited by 6 and mapped to 1202 other entries.

  20. 20
    "The human-bacterial pathogen protein interaction networks of Bacillus anthracis, Francisella tularensis, and Yersinia pestis."
    Dyer M.D., Neff C., Dufford M., Rivera C.G., Shattuck D., Bassaganya-Riera J., Murali T.M., Sobral B.W.
    PLoS ONE 5:e12089-e12089(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:P50213.

    This publication is mapped to 4890 other entries.

  21. 21
    "Fast kinase domain-containing protein 3 is a mitochondrial protein essential for cellular respiration."
    Simarro M., Gimenez-Cassina A., Kedersha N., Lazaro J.B., Adelmant G.O., Marto J.A., Rhee K., Tisdale S., Danial N., Benarafa C., Orduna A., Anderson P.
    Biochem. Biophys. Res. Commun. 401:440-446(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:P50213.

    This publication is cited by 9 and mapped to 83 other entries.

  22. 22
    Category: Function.
    Annotation: Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:3419.

    This publication is mapped to 3063 other entries.

  23. 23
    Category: Interaction.
    Source: IntAct:P50213.

    This publication is mapped to 2551 other entries.

  24. 24
    Category: Interaction.
    Source: IntAct:P50213.

    This publication is mapped to 455 other entries.

  25. 25
    "Aberrant IDH3alpha expression promotes malignant tumor growth by inducing HIF-1-mediated metabolic reprogramming and angiogenesis."
    Zeng L., Morinibu A., Kobayashi M., Zhu Y., Wang X., Goto Y., Yeom C.J., Zhao T., Hirota K., Shinomiya K., Itasaka S., Yoshimura M., Guo G., Hammond E.M., Hiraoka M., Harada H.
    Oncogene 34:4758-4766(2015) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: The silencing of IDH3a significantly delayed tumor growth by suppressing the HIF-1-mediated Warburg effect and angiogenesis.
    Source: GeneRIF:3419.

    This publication is mapped to 14 other entries.

1 to 25 of 26  Show
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