GNG4

Functionⁱ

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.Curated

GO - Molecular functionⁱ

G-protein beta-subunit binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
GTPase activity Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

G protein-coupled receptor signaling pathway Source: InterPro
negative regulation of cell growth
Source: BHF-UCL
Inferred from mutant phenotypeⁱ
- 15824735
regulation of G protein-coupled receptor signaling pathway
Source: ProtInc
Traceable author statementⁱ
- 7665596

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Transducer

Molecular function

Transducer

Enzyme and pathway databases

Reactomeⁱ	R-HSA-1296041 Activation of G protein gated Potassium channels R-HSA-163359 Glucagon signaling in metabolic regulation R-HSA-202040 G-protein activation R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-392170 ADP signalling through P2Y purinoceptor 12 R-HSA-392451 G beta:gamma signalling through PI3Kgamma R-HSA-392851 Prostacyclin signalling through prostacyclin receptor R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion R-HSA-4086398 Ca2+ pathway R-HSA-416476 G alpha (q) signalling events R-HSA-416482 G alpha (12/13) signalling events R-HSA-418217 G beta:gamma signalling through PLC beta R-HSA-418555 G alpha (s) signalling events R-HSA-418592 ADP signalling through P2Y purinoceptor 1 R-HSA-418594 G alpha (i) signalling events R-HSA-418597 G alpha (z) signalling events R-HSA-420092 Glucagon-type ligand receptors R-HSA-428930 Thromboxane signalling through TP receptor R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) R-HSA-500657 Presynaptic function of Kainate receptors R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
SignaLinkⁱ	P50150

Reactomeⁱ

R-HSA-1296041 Activation of G protein gated Potassium channels
R-HSA-163359 Glucagon signaling in metabolic regulation
R-HSA-202040 G-protein activation
R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
R-HSA-392170 ADP signalling through P2Y purinoceptor 12
R-HSA-392451 G beta:gamma signalling through PI3Kgamma
R-HSA-392851 Prostacyclin signalling through prostacyclin receptor
R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion
R-HSA-4086398 Ca2+ pathway
R-HSA-416476 G alpha (q) signalling events
R-HSA-416482 G alpha (12/13) signalling events
R-HSA-418217 G beta:gamma signalling through PLC beta
R-HSA-418555 G alpha (s) signalling events
R-HSA-418592 ADP signalling through P2Y purinoceptor 1
R-HSA-418594 G alpha (i) signalling events
R-HSA-418597 G alpha (z) signalling events
R-HSA-420092 Glucagon-type ligand receptors
R-HSA-428930 Thromboxane signalling through TP receptor
R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins
R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs)
R-HSA-500657 Presynaptic function of Kainate receptors
R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits

SignaLinkⁱ

P50150

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
Gene namesⁱ	Name:GNG4 Synonyms:GNGT4
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 1

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000168243.10
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:4407 GNG4
MIMⁱ	604388 gene
neXtProtⁱ	NX_P50150

Keywords - Cellular componentⁱ

Cell membrane, Membrane

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	2786
Open Targets More...OpenTargetsⁱ	ENSG00000168243
PharmGKBⁱ	PA28786

Polymorphism and mutation databases

BioMutaⁱ	GNG4
DMDMⁱ	1730219

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000012621	1 – 72	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4Add BLAST		72
PropeptideⁱPRO_0000012622	73 – 75	Removed in mature form		3

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	72	Cysteine methyl ester1 Publication		1
Lipidationⁱ	72	S-geranylgeranyl cysteine1 Publication		1

Keywords - PTMⁱ

Lipoprotein, Methylation, Prenylation

Proteomic databases

EPDⁱ	P50150
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P50150
PaxDbⁱ	P50150
PeptideAtlas More...PeptideAtlasⁱ	P50150
PRIDEⁱ	P50150
ProteomicsDBⁱ	56199

PTM databases

PhosphoSitePlusⁱ	P50150

PhosphoSitePlusⁱ

P50150

Expressionⁱ

Tissue specificityⁱ

Brain, kidney, pancreas, skeletal muscle and faintly in cardiac muscle.

Gene expression databases

Bgeeⁱ	ENSG00000168243 Expressed in 134 organ(s), highest expression level in forebrain
CleanExⁱ	HS_GNG4
ExpressionAtlasⁱ	P50150 baseline and differential
Genevisibleⁱ	P50150 HS

Interactionⁱ

Subunit structureⁱ

G proteins are composed of 3 units, alpha, beta and gamma. Interacts with beta-1 and beta-2, but not with beta-3 (PubMed:7665596). Interacts with KCNK1 (By similarity).By similarity1 Publication

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
Kcnk2	Q920B6	3	EBI-6395970,EBI-6530063	From Rattus norvegicus.

With

Entry

#Exp.

IntAct

Notes

Kcnk2

Q920B6

3

EBI-6395970,EBI-6530063

From Rattus norvegicus.

GO - Molecular functionⁱ

G-protein beta-subunit binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	109048, 20 interactors
IntActⁱ	P50150, 2 interactors
STRINGⁱ	9606.ENSP00000355556

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P50150
SMRⁱ	P50150
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the G protein gamma family.Curated

Phylogenomic databases

eggNOGⁱ	KOG4119 Eukaryota ENOG41122JF LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119218
HOVERGENⁱ	HBG014983
InParanoidⁱ	P50150
KEGG Orthology (KO) More...KOⁱ	K04541
OMAⁱ	EVMSNNS
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G17J0
PhylomeDBⁱ	P50150
TreeFamⁱ	TF319909

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00068 GGL, 1 hit
Gene3Dⁱ	4.10.260.10, 1 hit
InterProⁱ	View protein in InterPro IPR015898 G-protein_gamma-like_dom IPR036284 GGL_sf IPR001770 Gprotein-gamma
PANTHERⁱ	PTHR13809 PTHR13809, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00631 G-gamma, 1 hit
PRINTSⁱ	PR00321 GPROTEING
SMARTⁱ	View protein in SMART SM00224 GGL, 1 hit
SUPFAMⁱ	SSF48670 SSF48670, 1 hit
PROSITEⁱ	View protein in PROSITE PS50058 G_PROTEIN_GAMMA, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

P50150-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MKEGMSNNST TSISQARKAV EQLKMEACMD RVKVSQAAAD LLAYCEAHVR 
        60         70 
EDPLIIPVPA SENPFREKKF FCTIL

Length:75

Mass (Da):8,389

Last modified:October 1, 1996 - v1

Checksum:ⁱ42FAEF4728F83FF5

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U31382 mRNA Translation: AAC50204.1 AF493872 mRNA Translation: AAM12586.1 BC022485 mRNA Translation: AAH22485.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS1607.1
PIRⁱ	I39157
NCBI Reference Sequences More...RefSeqⁱ	NP_001092191.1, NM_001098721.1 NP_001092192.1, NM_001098722.1 NP_004476.1, NM_004485.3 XP_006711824.1, XM_006711761.2 XP_011542469.1, XM_011544167.2
UniGeneⁱ	Hs.159711

Genome annotation databases

Ensemblⁱ	ENST00000366597; ENSP00000355556; ENSG00000168243 ENST00000366598; ENSP00000355557; ENSG00000168243 ENST00000391854; ENSP00000375727; ENSG00000168243 ENST00000450593; ENSP00000398629; ENSG00000168243 ENST00000484517; ENSP00000482192; ENSG00000168243 ENST00000634574; ENSP00000489027; ENSG00000282972 ENST00000635006; ENSP00000489228; ENSG00000282972 ENST00000635235; ENSP00000489454; ENSG00000282972 ENST00000635387; ENSP00000489307; ENSG00000282972 ENST00000635595; ENSP00000489194; ENSG00000282972
GeneIDⁱ	2786
KEGGⁱ	hsa:2786
UCSC genome browser More...UCSCⁱ	uc001hxe.5 human

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P50150	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4		PONAB		75	UniRef100_P50150
Guanine nucleotide-binding protein subunit gamma		HUMAN		75
Guanine nucleotide-binding protein subunit gamma		CALJA		75
Guanine nucleotide-binding protein subunit gamma		PANTR		75
Guanine nucleotide-binding protein subunit gamma		ERIEU		75
+14

Protein	Similar proteins		Species	Score	Length	Source
P50150	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4		PONAB		75	UniRef90_P50150
Guanine nucleotide-binding protein subunit gamma		HUMAN		75
Guanine nucleotide-binding protein subunit gamma		CALJA		75
Guanine nucleotide-binding protein subunit gamma		PANTR		75
Guanine nucleotide-binding protein subunit gamma		ERIEU		75
+18

Protein	Similar proteins		Species	Score	Length	Source
P50150	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4		PONAB		75	UniRef50_P50150
Guanine nucleotide-binding protein subunit gamma		HUMAN		75
Guanine nucleotide-binding protein subunit gamma		CALJA		75
Guanine nucleotide-binding protein subunit gamma		PANTR		75
Guanine nucleotide-binding protein subunit gamma		ERIEU		75
+20

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U31382 mRNA Translation: AAC50204.1 AF493872 mRNA Translation: AAM12586.1 BC022485 mRNA Translation: AAH22485.1
CCDSⁱ	CCDS1607.1
PIRⁱ	I39157
RefSeqⁱ	NP_001092191.1, NM_001098721.1 NP_001092192.1, NM_001098722.1 NP_004476.1, NM_004485.3 XP_006711824.1, XM_006711761.2 XP_011542469.1, XM_011544167.2
UniGeneⁱ	Hs.159711

3D structure databases

ProteinModelPortalⁱ	P50150
SMRⁱ	P50150
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	109048, 20 interactors
IntActⁱ	P50150, 2 interactors
STRINGⁱ	9606.ENSP00000355556

PTM databases

PhosphoSitePlusⁱ	P50150

PhosphoSitePlusⁱ

P50150

Polymorphism and mutation databases

BioMutaⁱ	GNG4
DMDMⁱ	1730219

Proteomic databases

EPDⁱ	P50150
MaxQBⁱ	P50150
PaxDbⁱ	P50150
PeptideAtlasⁱ	P50150
PRIDEⁱ	P50150
ProteomicsDBⁱ	56199

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	2786
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000366597; ENSP00000355556; ENSG00000168243 ENST00000366598; ENSP00000355557; ENSG00000168243 ENST00000391854; ENSP00000375727; ENSG00000168243 ENST00000450593; ENSP00000398629; ENSG00000168243 ENST00000484517; ENSP00000482192; ENSG00000168243 ENST00000634574; ENSP00000489027; ENSG00000282972 ENST00000635006; ENSP00000489228; ENSG00000282972 ENST00000635235; ENSP00000489454; ENSG00000282972 ENST00000635387; ENSP00000489307; ENSG00000282972 ENST00000635595; ENSP00000489194; ENSG00000282972
GeneIDⁱ	2786
KEGGⁱ	hsa:2786
UCSCⁱ	uc001hxe.5 human

Organism-specific databases

CTDⁱ	2786
DisGeNETⁱ	2786
EuPathDBⁱ	HostDB:ENSG00000168243.10
GeneCardsⁱ	GNG4
HGNCⁱ	HGNC:4407 GNG4
MIMⁱ	604388 gene
neXtProtⁱ	NX_P50150
OpenTargetsⁱ	ENSG00000168243
PharmGKBⁱ	PA28786
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG4119 Eukaryota ENOG41122JF LUCA
GeneTreeⁱ	ENSGT00760000119218
HOVERGENⁱ	HBG014983
InParanoidⁱ	P50150
KOⁱ	K04541
OMAⁱ	EVMSNNS
OrthoDBⁱ	EOG091G17J0
PhylomeDBⁱ	P50150
TreeFamⁱ	TF319909

Enzyme and pathway databases

Reactomeⁱ	R-HSA-1296041 Activation of G protein gated Potassium channels R-HSA-163359 Glucagon signaling in metabolic regulation R-HSA-202040 G-protein activation R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-392170 ADP signalling through P2Y purinoceptor 12 R-HSA-392451 G beta:gamma signalling through PI3Kgamma R-HSA-392851 Prostacyclin signalling through prostacyclin receptor R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion R-HSA-4086398 Ca2+ pathway R-HSA-416476 G alpha (q) signalling events R-HSA-416482 G alpha (12/13) signalling events R-HSA-418217 G beta:gamma signalling through PLC beta R-HSA-418555 G alpha (s) signalling events R-HSA-418592 ADP signalling through P2Y purinoceptor 1 R-HSA-418594 G alpha (i) signalling events R-HSA-418597 G alpha (z) signalling events R-HSA-420092 Glucagon-type ligand receptors R-HSA-428930 Thromboxane signalling through TP receptor R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) R-HSA-500657 Presynaptic function of Kainate receptors R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
SignaLinkⁱ	P50150

Reactomeⁱ

R-HSA-1296041 Activation of G protein gated Potassium channels
R-HSA-163359 Glucagon signaling in metabolic regulation
R-HSA-202040 G-protein activation
R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
R-HSA-392170 ADP signalling through P2Y purinoceptor 12
R-HSA-392451 G beta:gamma signalling through PI3Kgamma
R-HSA-392851 Prostacyclin signalling through prostacyclin receptor
R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion
R-HSA-4086398 Ca2+ pathway
R-HSA-416476 G alpha (q) signalling events
R-HSA-416482 G alpha (12/13) signalling events
R-HSA-418217 G beta:gamma signalling through PLC beta
R-HSA-418555 G alpha (s) signalling events
R-HSA-418592 ADP signalling through P2Y purinoceptor 1
R-HSA-418594 G alpha (i) signalling events
R-HSA-418597 G alpha (z) signalling events
R-HSA-420092 Glucagon-type ligand receptors
R-HSA-428930 Thromboxane signalling through TP receptor
R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins
R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs)
R-HSA-500657 Presynaptic function of Kainate receptors
R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
R-HSA-997272 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits

SignaLinkⁱ

P50150

Miscellaneous databases

ChiTaRSⁱ	GNG4 human
GenomeRNAiⁱ	2786
Protein Ontology More...PROⁱ	PR:P50150
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000168243 Expressed in 134 organ(s), highest expression level in forebrain
CleanExⁱ	HS_GNG4
ExpressionAtlasⁱ	P50150 baseline and differential
Genevisibleⁱ	P50150 HS

Family and domain databases

CDDⁱ	cd00068 GGL, 1 hit
Gene3Dⁱ	4.10.260.10, 1 hit
InterProⁱ	View protein in InterPro IPR015898 G-protein_gamma-like_dom IPR036284 GGL_sf IPR001770 Gprotein-gamma
PANTHERⁱ	PTHR13809 PTHR13809, 1 hit
Pfamⁱ	View protein in Pfam PF00631 G-gamma, 1 hit
PRINTSⁱ	PR00321 GPROTEING
SMARTⁱ	View protein in SMART SM00224 GGL, 1 hit
SUPFAMⁱ	SSF48670 SSF48670, 1 hit
PROSITEⁱ	View protein in PROSITE PS50058 G_PROTEIN_GAMMA, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	GBG4_HUMAN
Accessionⁱ	P50150Primary (citable) accession number: P50150
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
	Last sequence update:	October 1, 1996
	Last modified:	November 7, 2018
	This is version 167 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

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UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P50150 (GBG4_HUMAN)

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Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma membrane

Extracellular region or secreted

Plasma Membrane

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ