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Entry version 162 (08 May 2019)
Sequence version 3 (23 Jan 2007)
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Protein

Retinol-binding protein 2

Gene

RBP2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Intracellular transport of retinol.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei41Retinoic acid1
Binding sitei109Retinoic acidBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTransport
LigandRetinol-binding, Vitamin A

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
MetaCyc:ENSG00000114113-MONOMER

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-975634 Retinoid metabolism and transport

Protein family/group databases

Transport Classification Database

More...
TCDBi
8.A.33.1.3 the fatty acid binding protein (fabp) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Retinol-binding protein 2
Alternative name(s):
Cellular retinol-binding protein II
Short name:
CRBP-II
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RBP2
Synonyms:CRBP2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:9920 RBP2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
180280 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P50120

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
5948

Open Targets

More...
OpenTargetsi
ENSG00000114113

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34287

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB00162 Vitamin A

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RBP2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
62297500

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000673951 – 134Retinol-binding protein 2Add BLAST134

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P50120

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P50120

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P50120

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P50120

PeptideAtlas

More...
PeptideAtlasi
P50120

PRoteomics IDEntifications database

More...
PRIDEi
P50120

ProteomicsDB human proteome resource

More...
ProteomicsDBi
56194

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P50120

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P50120

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Higher expression in adult small intestine and to a much lesser extent in fetal kidney.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000114113 Expressed in 105 organ(s), highest expression level in duodenum

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P50120 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P50120 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA035866

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
111882, 3 interactors

Protein interaction database and analysis system

More...
IntActi
P50120, 3 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000232217

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1134
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2RCQX-ray1.20A2-134[»]
2RCTX-ray1.20A2-134[»]
4EDEX-ray1.40A/B2-134[»]
4EEJX-ray1.50A/B2-134[»]
4EFGX-ray1.58A/B2-134[»]
4EXZX-ray1.61A/B2-134[»]
4GKCX-ray1.30A/B2-134[»]
4QYNX-ray1.19A/B2-134[»]
4QYPX-ray1.62A/B/C/D2-134[»]
4QZTX-ray1.90A/B/C/D2-134[»]
4QZUX-ray1.50A/B/C/D2-134[»]
4RUUX-ray1.40A/B2-134[»]
4ZCBX-ray1.70A/B2-134[»]
4ZGUX-ray1.49A/B/C/D2-134[»]
4ZH6X-ray1.55A2-134[»]
4ZH9X-ray2.66A2-134[»]
4ZJ0X-ray1.50A/B2-134[»]
4ZR2X-ray1.80A/B2-134[»]
5DG4X-ray1.50A/B/C/D2-134[»]
5DPQX-ray1.77A/B2-134[»]
5F58X-ray1.54A/B2-134[»]
5F6BX-ray1.31A/B2-134[»]
5F7GX-ray1.48A/B2-134[»]
5FAZX-ray1.40A/B2-134[»]
5FENX-ray1.55A/B2-134[»]
5FFHX-ray1.68A/B2-134[»]
5U6GX-ray2.60A/B/C/D/E/F/G/H/I/J/K/L2-134[»]
6BTHX-ray1.35A/B1-134[»]
6BTIX-ray1.45A/B1-134[»]
6C7ZX-ray1.42A/B2-134[»]

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P50120

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P50120

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4015 Eukaryota
ENOG4111US8 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160165

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000004831

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P50120

KEGG Orthology (KO)

More...
KOi
K14622

Identification of Orthologs from Complete Genome Data

More...
OMAi
WKQWVEG

Database of Orthologous Groups

More...
OrthoDBi
1417203at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P50120

TreeFam database of animal gene trees

More...
TreeFami
TF316894

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.128.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012674 Calycin
IPR000463 Fatty_acid-bd
IPR031259 ILBP
IPR000566 Lipocln_cytosolic_FA-bd_dom

The PANTHER Classification System

More...
PANTHERi
PTHR11955 PTHR11955, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00061 Lipocalin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00178 FATTYACIDBP

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50814 SSF50814, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00214 FABP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

P50120-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTRDQNGTWE MESNENFEGY MKALDIDFAT RKIAVRLTQT KVIDQDGDNF
60 70 80 90 100
KTKTTSTFRN YDVDFTVGVE FDEYTKSLDN RHVKALVTWE GDVLVCVQKG
110 120 130
EKENRGWKQW IEGDKLYLEL TCGDQVCRQV FKKK
Length:134
Mass (Da):15,707
Last modified:January 23, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA4A7FB157B099A7D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RB89D6RB89_HUMAN
Retinol-binding protein 2
RBP2
103Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RGE6D6RGE6_HUMAN
Retinol-binding protein 2
RBP2
24Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti31R → P in AAC50162 (PubMed:7657783).Curated1
Sequence conflicti114D → G in AAH69396 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U13831 mRNA Translation: AAC50162.1
AK291978 mRNA Translation: BAF84667.1
CH471052 Genomic DNA Translation: EAW79036.1
BC069296 mRNA Translation: AAH69296.1
BC069361 mRNA Translation: AAH69361.1
BC069396 mRNA Translation: AAH69396.1
BC069424 mRNA Translation: AAH69424.1
BC069447 mRNA Translation: AAH69447.1
BC069513 mRNA Translation: AAH69513.1
BC069522 mRNA Translation: AAH69522.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3109.1

NCBI Reference Sequences

More...
RefSeqi
NP_004155.2, NM_004164.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000232217; ENSP00000232217; ENSG00000114113

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
5948

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:5948

UCSC genome browser

More...
UCSCi
uc003eth.4 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U13831 mRNA Translation: AAC50162.1
AK291978 mRNA Translation: BAF84667.1
CH471052 Genomic DNA Translation: EAW79036.1
BC069296 mRNA Translation: AAH69296.1
BC069361 mRNA Translation: AAH69361.1
BC069396 mRNA Translation: AAH69396.1
BC069424 mRNA Translation: AAH69424.1
BC069447 mRNA Translation: AAH69447.1
BC069513 mRNA Translation: AAH69513.1
BC069522 mRNA Translation: AAH69522.1
CCDSiCCDS3109.1
RefSeqiNP_004155.2, NM_004164.2

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2RCQX-ray1.20A2-134[»]
2RCTX-ray1.20A2-134[»]
4EDEX-ray1.40A/B2-134[»]
4EEJX-ray1.50A/B2-134[»]
4EFGX-ray1.58A/B2-134[»]
4EXZX-ray1.61A/B2-134[»]
4GKCX-ray1.30A/B2-134[»]
4QYNX-ray1.19A/B2-134[»]
4QYPX-ray1.62A/B/C/D2-134[»]
4QZTX-ray1.90A/B/C/D2-134[»]
4QZUX-ray1.50A/B/C/D2-134[»]
4RUUX-ray1.40A/B2-134[»]
4ZCBX-ray1.70A/B2-134[»]
4ZGUX-ray1.49A/B/C/D2-134[»]
4ZH6X-ray1.55A2-134[»]
4ZH9X-ray2.66A2-134[»]
4ZJ0X-ray1.50A/B2-134[»]
4ZR2X-ray1.80A/B2-134[»]
5DG4X-ray1.50A/B/C/D2-134[»]
5DPQX-ray1.77A/B2-134[»]
5F58X-ray1.54A/B2-134[»]
5F6BX-ray1.31A/B2-134[»]
5F7GX-ray1.48A/B2-134[»]
5FAZX-ray1.40A/B2-134[»]
5FENX-ray1.55A/B2-134[»]
5FFHX-ray1.68A/B2-134[»]
5U6GX-ray2.60A/B/C/D/E/F/G/H/I/J/K/L2-134[»]
6BTHX-ray1.35A/B1-134[»]
6BTIX-ray1.45A/B1-134[»]
6C7ZX-ray1.42A/B2-134[»]
SMRiP50120
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi111882, 3 interactors
IntActiP50120, 3 interactors
STRINGi9606.ENSP00000232217

Chemistry databases

DrugBankiDB00162 Vitamin A

Protein family/group databases

TCDBi8.A.33.1.3 the fatty acid binding protein (fabp) family

PTM databases

iPTMnetiP50120
PhosphoSitePlusiP50120

Polymorphism and mutation databases

BioMutaiRBP2
DMDMi62297500

Proteomic databases

EPDiP50120
jPOSTiP50120
MaxQBiP50120
PaxDbiP50120
PeptideAtlasiP50120
PRIDEiP50120
ProteomicsDBi56194

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
5948
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000232217; ENSP00000232217; ENSG00000114113
GeneIDi5948
KEGGihsa:5948
UCSCiuc003eth.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
5948
DisGeNETi5948

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RBP2
HGNCiHGNC:9920 RBP2
HPAiHPA035866
MIMi180280 gene
neXtProtiNX_P50120
OpenTargetsiENSG00000114113
PharmGKBiPA34287

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4015 Eukaryota
ENOG4111US8 LUCA
GeneTreeiENSGT00940000160165
HOGENOMiHOG000004831
InParanoidiP50120
KOiK14622
OMAiWKQWVEG
OrthoDBi1417203at2759
PhylomeDBiP50120
TreeFamiTF316894

Enzyme and pathway databases

BioCyciMetaCyc:ENSG00000114113-MONOMER
ReactomeiR-HSA-975634 Retinoid metabolism and transport

Miscellaneous databases

EvolutionaryTraceiP50120

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
RBP2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
5948

Protein Ontology

More...
PROi
PR:P50120

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
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Gene expression databases

BgeeiENSG00000114113 Expressed in 105 organ(s), highest expression level in duodenum
ExpressionAtlasiP50120 baseline and differential
GenevisibleiP50120 HS

Family and domain databases

Gene3Di2.40.128.20, 1 hit
InterProiView protein in InterPro
IPR012674 Calycin
IPR000463 Fatty_acid-bd
IPR031259 ILBP
IPR000566 Lipocln_cytosolic_FA-bd_dom
PANTHERiPTHR11955 PTHR11955, 1 hit
PfamiView protein in Pfam
PF00061 Lipocalin, 1 hit
PRINTSiPR00178 FATTYACIDBP
SUPFAMiSSF50814 SSF50814, 1 hit
PROSITEiView protein in PROSITE
PS00214 FABP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRET2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P50120
Secondary accession number(s): A8K7G3, Q6ISQ9, Q6ISS7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: January 23, 2007
Last modified: May 8, 2019
This is version 162 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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