Sorting assembly machinery 37 kDa subunit

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

Miscellaneous

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• mitochondrial outer membrane translocase complex assembly Source: SGD <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypeⁱ
  • Ref.6

    "Machinery for protein sorting and assembly in the mitochondrial outer membrane."
    Wiedemann N., Kozjak V., Chacinska A., Schoenfisch B., Rospert S., Ryan M.T., Pfanner N., Meisinger C.
    Nature 424:565-571(2003) [PubMed] [Europe PMC] [Abstract]

    Cited for: IDENTIFICATION IN THE SAM COMPLEX, FUNCTION OF THE SAM COMPLEX.
  • "Alternative function for the mitochondrial SAM complex in biogenesis of alpha-helical TOM proteins."
    Stojanovski D., Guiard B., Kozjak-Pavlovic V., Pfanner N., Meisinger C.
    J Cell Biol 179:881-893(2007) [PubMed] [Europe PMC] [Abstract]
• mitochondrion organization Source: GO_Central <p>Inferred from Biological aspect of Ancestor</p> <p>A type of phylogenetic evidence whereby an aspect of a descendent is inferred through the characterization of an aspect of a ancestral gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#iba">GO evidence code guide</a></p> Inferred from biological aspect of ancestorⁱ
  • "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief Bioinform 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]
• phospholipid transport Source: SGDInferred from mutant phenotypeⁱ
  • "Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2."
    Dagley M.J., Gentle I.E., Beilharz T.H., Pettolino F.A., Djordjevic J.T., Lo T.L., Uwamahoro N., Rupasinghe T., Tull D.L., McConville M., Beaurepaire C., Nantel A., Lithgow T., Mitchell A.P., Traven A.
    Mol Microbiol 79:968-989(2011) [PubMed] [Europe PMC] [Abstract]
• protein import into mitochondrial matrix Source: ComplexPortal <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • "Coupling of mitochondrial import and export translocases by receptor-mediated supercomplex formation."
    Qiu J., Wenz L.S., Zerbes R.M., Oeljeklaus S., Bohnert M., Stroud D.A., Wirth C., Ellenrieder L., Thornton N., Kutik S., Wiese S., Schulze-Specking A., Zufall N., Chacinska A., Guiard B., Hunte C., Warscheid B., van der Laan M.

    , Pfanner N., Wiedemann N., Becker T.
    Cell 154:596-608(2013) [PubMed] [Europe PMC] [Abstract]
• protein insertion into mitochondrial outer membrane Source: SGDInferred from mutant phenotypeⁱ
  • "Alternative function for the mitochondrial SAM complex in biogenesis of alpha-helical TOM proteins."
    Stojanovski D., Guiard B., Kozjak-Pavlovic V., Pfanner N., Meisinger C.
    J Cell Biol 179:881-893(2007) [PubMed] [Europe PMC] [Abstract]

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

• UniProt annotation
• GO - Cellular component

Topology

Keywords - Cellular componentⁱ

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structureⁱ

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsⁱ

Protein-protein interaction databases

Miscellaneous databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

Secondary structure

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MVKGSVHLWG KDGKASLISV DSIALVWFIK LCTSEEAKSM VAGLQIVFSN 
        60         70         80         90        100
NTDLSSDGKL PVLILDNGTK VSGYVNIVQF LHKNICTSKY EKGTDYEEDL 
       110        120        130        140        150
AIVRKKDRLL EYSLLNYVDV EISRLTDYQL FLNTKNYNEY TKKLFSKLLY 
       160        170        180        190        200
FPMWYNTPLQ LRSQARENCE EIIGSLTLED DEEFVESKAM ESASQLAQSK 
       210        220        230        240        250
TFKIAHKNKI KGKQELQQVK YNLQFDNRLQ SCVSNWLAAR KKLDDSVILS 
       260        270        280        290        300
SDLLFLANLY VQLGLPDGNR IRSKLEQTFG SELLNSMSNK IDDFVHRPSN 
       310        320 
NLEQRDPQFR EQGNVVMSLY NLACKYI                          

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 100% Identity
• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Proteomic databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

Keywords - Technical termⁱ

Documents

1. Yeast
   Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
2. Yeast chromosome XIII
   Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names
3. PDB cross-references
   Index of Protein Data Bank (PDB) cross-references