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Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Acts as a chaperone.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAGRO:ATU0122-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaK
Alternative name(s):
HSP70
Heat shock 70 kDa protein
Heat shock protein 70
Gene namesi
Name:dnaK
Ordered Locus Names:Atu0122
ORF Names:AGR_C_195
OrganismiAgrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Taxonomic identifieri176299 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex
Proteomesi
  • UP000000813 Componenti: Chromosome circular

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000784051 – 633Chaperone protein DnaKAdd BLAST633

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei198Phosphothreonine; by autocatalysisBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiP50019

Expressioni

Inductioni

By heat shock.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi176299.Atu0122

Structurei

3D structure databases

ProteinModelPortaliP50019
SMRiP50019
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Phylogenomic databases

eggNOGiENOG4105CFG Bacteria
COG0443 LUCA
HOGENOMiHOG000228136
KOiK04043
OMAiISIKRHM

Family and domain databases

Gene3Di1.20.1270.10, 1 hit
2.60.34.10, 1 hit
HAMAPiMF_00332 DnaK, 1 hit
InterProiView protein in InterPro
IPR012725 Chaperone_DnaK
IPR018181 Heat_shock_70_CS
IPR029048 HSP70_C_sf
IPR029047 HSP70_peptide-bd_sf
IPR013126 Hsp_70_fam
PANTHERiPTHR19375 PTHR19375, 1 hit
PfamiView protein in Pfam
PF00012 HSP70, 1 hit
PRINTSiPR00301 HEATSHOCK70
SUPFAMiSSF100920 SSF100920, 1 hit
SSF100934 SSF100934, 1 hit
TIGRFAMsiTIGR02350 prok_dnaK, 1 hit
PROSITEiView protein in PROSITE
PS00297 HSP70_1, 1 hit
PS00329 HSP70_2, 1 hit
PS01036 HSP70_3, 1 hit

Sequencei

Sequence statusi: Complete.

P50019-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKVIGIDLG TTNSCVAVMD GKDTKVIENA EGARTTPSMV AFSDDGERLV
60 70 80 90 100
GQPAKRQAVT NPTNTLFAVK RLIGRRYEDP TVEKDKALVP FEIVKGDNGD
110 120 130 140 150
AWVKAQDKNY SPSQISAMIL QKMKETAESY LGEKVEKAVI TVPAYFNDAQ
160 170 180 190 200
RQATKDAGRI AGLDVLRIIN EPTAAALAYG LDKKEGKTIA VYDLGGGTFD
210 220 230 240 250
ISVLEIGDGV FEVKSTNGDT FLGGEDFDMR LVEYLAGEFK KDQGIDLKND
260 270 280 290 300
KLALQRLKEA AEKAKIELSS SQQTEINLPF ITADASGPKH LTLKLTRAKF
310 320 330 340 350
ESLVDDLVQR TVAPCKAALK DAGVTAAEID EVVLVGGMSR MPKVQEVVKQ
360 370 380 390 400
LFGKEPHKGV NPDEVVAMGA AIQAGVLQGD VKDVLLLDVT PLSLGIETLG
410 420 430 440 450
GVFTRLIDRN TTIPTKKSQT FSTAEDNQSA VTIRVSQGER EMAQDNKLLG
460 470 480 490 500
QFDLVGLPPS PRGVPQIEVT FDIDANGIVQ VSAKDKGTGK EQQIRIQASG
510 520 530 540 550
GLSDADIEKM VKDAEANAEA DKKRRAGVEA KNQAESLIHS TEKSVKEYGD
560 570 580 590 600
KVSETDRKAI EDAIASLKTA VEAAEPDADD IQAKTQTLME VSMKLGQAIY
610 620 630
EAQQAEAGDA SAEGKDDVVD ADYEEIKDDK KSA
Length:633
Mass (Da):68,080
Last modified:March 27, 2002 - v2
Checksum:iD53CC7E6EB3B50E3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti293L → P in CAA60592 (PubMed:7592349).Curated1
Sequence conflicti345Q → R in CAA60592 (PubMed:7592349).Curated1
Sequence conflicti463G → A in CAA60592 (PubMed:7592349).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X87113 Genomic DNA Translation: CAA60592.1
AE007869 Genomic DNA Translation: AAK85942.1
PIRiAE2591
E97373
I39585
RefSeqiNP_353157.1, NC_003062.2
WP_006309946.1, NC_003062.2

Genome annotation databases

EnsemblBacteriaiAAK85942; AAK85942; Atu0122
GeneIDi1132160
KEGGiatu:Atu0122
PATRICifig|176299.10.peg.114

Similar proteinsi

Entry informationi

Entry nameiDNAK_AGRFC
AccessioniPrimary (citable) accession number: P50019
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: March 27, 2002
Last modified: February 28, 2018
This is version 114 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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