Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
1 to 25 of 38  Show
  1. 1
    "Identification of tuberous sclerosis 2 messenger RNA splice variants that are conserved and differentially expressed in rat and human tissues."
    Xiao G.-H., Jin F., Yeung R.S.
    Cell Growth Differ. 6:1185-1191(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3 AND 4), DISEASE.
    Category: Pathology & Biotech, Sequences.
    Strain: Wistar.
    Tissue: Kidney.
    Source: UniProtKB/Swiss-Prot (reviewed).
  2. 2
    "cDNA structure, alternative splicing and exon-intron organization of the predisposing tuberous sclerosis (Tsc2) gene of the Eker rat model."
    Kobayashi T., Nishizawa M., Hirayama Y., Kobayashi E., Hino O.
    Nucleic Acids Res. 23:2608-2613(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Category: Sequences.
    Strain: Long Evans.
    Tissue: Brain and Kidney.
    Source: UniProtKB/Swiss-Prot (reviewed).
  3. 3
    "The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis."
    Xiao G.-H., Shoarinejad F., Jin F., Golemis E.A., Yeung R.S.
    J. Biol. Chem. 272:6097-6100(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH RABEP1.
    Category: Function, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 and mapped to 1 other entries.

  4. 4
    "Isolation and characterization of a rat homologue of the human tuberous sclerosis 1 gene (Tsc1) and analysis of its mutations in rat renal carcinomas."
    Satake N., Kobayashi T., Kobayashi E., Izumi K., Hino O.
    Cancer Res. 59:849-855(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: MUTAGENESIS OF ASN-314 AND LEU-713.
    Category: Pathology & Biotech.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 1 other entries.

  5. 5
    "Regulation of microtubule-dependent protein transport by the TSC2/mammalian target of rapamycin pathway."
    Jiang X., Yeung R.S.
    Cancer Res. 66:5258-5269(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3 other entries.

  6. 6
    "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues."
    Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C., Olsen J.V.
    Nat. Commun. 3:876-876(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1389 AND SER-1413, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 6815 other entries.

  7. 7
    "Loss of tuberin, the tuberous-sclerosis-complex-2 gene product is associated with angiogenesis."
    Nguyen-Vu P.A., Fackler I., Rust A., DeClue J.E., Sander C.A., Volkenandt M., Flaig M., Yeung R.S., Wienecke R.
    J. Cutan. Pathol. 28:470-475(2001) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: RGD:3908.

    This publication is mapped to 2 other entries.

  8. 8
    "Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM)."
    Goncharova E.A., Goncharov D.A., Eszterhas A., Hunter D.S., Glassberg M.K., Yeung R.S., Walker C.L., Noonan D., Kwiatkowski D.J., Chou M.M., Panettieri R.A. Jr., Krymskaya V.P.
    J. Biol. Chem. 277:30958-30967(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: RGD:3908.

    This publication is mapped to 2 other entries.

  9. 9
    "Multicompartmental distribution of the tuberous sclerosis gene products, hamartin and tuberin."
    Yamamoto Y., Jones K.A., Mak B.C., Muehlenbachs A., Yeung R.S.
    Arch. Biochem. Biophys. 404:210-217(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location.
    Source: RGD:3908.

    This publication is mapped to 3 other entries.

  10. 10
    Category: Interaction.
    Source: IntAct:P49816.

    This publication is mapped to 15 other entries.

  11. 11
    "The tuberin-hamartin complex negatively regulates beta-catenin signaling activity."
    Mak B.C., Takemaru K., Kenerson H.L., Moon R.T., Yeung R.S.
    J. Biol. Chem. 278:5947-5951(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: RGD:3908.

    This publication is mapped to 2 other entries.

  12. 12
    "Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling."
    Inoki K., Li Y., Xu T., Guan K.-L.
    Genes Dev. 17:1829-1834(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: RGD:3908.

    This publication is mapped to 21 other entries.

  13. 13
    "Pam and its ortholog highwire interact with and may negatively regulate the TSC1.TSC2 complex."
    Murthy V., Han S., Beauchamp R.L., Smith N., Haddad L.A., Ito N., Ramesh V.
    J. Biol. Chem. 279:1351-1358(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location, Interaction.
    Source: RGD:3908.

    This publication is mapped to 13 other entries.

  14. 14
    "Tuberous sclerosis-2 tumor suppressor modulates ERK and B-Raf activity in transformed renal epithelial cells."
    Yoon H.S., Ramachandiran S., Chacko M.A., Monks T.J., Lau S.S.
    Am. J. Physiol. Renal Physiol. 286:F417-24(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: RGD:3908.

    This publication is mapped to 2 other entries.

  15. 15
    "Tuberin is a component of lipid rafts and mediates caveolin-1 localization: role of TSC2 in post-Golgi transport."
    Jones K.A., Jiang X., Yamamoto Y., Yeung R.S.
    Exp. Cell Res. 295:512-524(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Subcellular Location, Interaction.
    Source: RGD:3908.

    This publication is mapped to 2 other entries.

  16. 16
    "Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites."
    Takei N., Inamura N., Kawamura M., Namba H., Hara K., Yonezawa K., Nawa H.
    J. Neurosci. 24:9760-9769(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location.
    Source: RGD:3908.

    This publication is mapped to 14 other entries.

  17. 17
    "Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2."
    Tavazoie S.F., Alvarez V.A., Ridenour D.A., Kwiatkowski D.J., Sabatini B.L.
    Nat. Neurosci. 8:1727-1734(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: RGD:3908.

    This publication is mapped to 42 other entries.

  18. 18
    "Mutual information-based feature selection in studying perturbation of dendritic structure caused by TSC2 inactivation."
    Zhou X., Zhu J., Liu K.Y., Sabatini B.L., Wong S.T.
    Neuroinformatics 4:81-94(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: RGD:3908.

    This publication is mapped to 2 other entries.

  19. 19
    "TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth."
    Inoki K., Ouyang H., Zhu T., Lindvall C., Wang Y., Zhang X., Yang Q., Bennett C., Harada Y., Stankunas K., Wang C.Y., He X., MacDougald O.A., You M., Williams B.O., Guan K.L.
    Cell 126:955-968(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:P49816.

    This publication is mapped to 1 other entry.

  20. 20
    "Antisense suppression of TSC1 gene product, hamartin, enhances neurite outgrowth in NGF-treated PC12h cells."
    Floricel F., Higaki K., Maki H., Nanba E., Ninomiya H., Ohno K.
    Brain Dev. 29:502-509(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Subcellular Location.
    Source: RGD:3908.

    This publication is mapped to 3 other entries.

  21. 21
    "N-terminal hamartin-binding and C-terminal GAP domain of tuberin can separate in vivo."
    Momose S., Kobayashi T., Tada N., Itoyama S., Hino O.
    Biochem. Biophys. Res. Commun. 356:693-698(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Subcellular Location, Interaction.
    Source: RGD:3908.

    This publication is mapped to 3 other entries.

  22. 22
    "c-myc Repression of TSC2 contributes to control of translation initiation and Myc-induced transformation."
    Ravitz M.J., Chen L., Lynch M., Schmidt E.V.
    Cancer Res. 67:11209-11217(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: RGD:3908.

    This publication is mapped to 2 other entries.

  23. 23
    "Mechanism of oxidative DNA damage in diabetes: tuberin inactivation and downregulation of DNA repair enzyme 8-oxo-7,8-dihydro-2'-deoxyguanosine-DNA glycosylase."
    Simone S., Gorin Y., Velagapudi C., Abboud H.E., Habib S.L.
    Diabetes 57:2626-2636(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Source: RGD:3908.

    This publication is mapped to 4 other entries.

  24. 24
    "The G1556S-type tuberin variant suppresses tumor formation in tuberous sclerosis 2 mutant (Eker) rats despite its deficiency in mTOR inhibition."
    Shiono M., Kobayashi T., Takahashi R., Sun G., Abe M., Zhang D., Wang L., Piao X., Takagi Y., Mineki R., Taka H., Tada N., Sonobe S., Momose S., Ueda M., Hino O.
    Oncogene 27:6690-6697(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Source: RGD:3908.

    This publication is mapped to 2 other entries.

  25. 25
    "Tuberous sclerosis complex proteins control axon formation."
    Choi Y.J., Di Nardo A., Kramvis I., Meikle L., Kwiatkowski D.J., Sahin M., He X.
    Genes Dev. 22:2485-2495(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Source: RGD:3908.

    This publication is cited by 1 and mapped to 36 other entries.

1 to 25 of 38  Show
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again