EIF2B2

Functionⁱ

Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.

GO - Molecular functionⁱ

ATP binding
Source: UniProtKB
Inferred from direct assayⁱ
- 11323413
GTP binding
Source: UniProtKB
Inferred from direct assayⁱ
- 11323413
translation initiation factor activity Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

central nervous system development
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 15776425
myelination
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 14566705
oligodendrocyte development
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 15217090
ovarian follicle development
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 15507143
regulation of translational initiation
Source: UniProtKB
Traceable author statementⁱ
- 15060152
response to glucose Source: UniProtKB
response to heat Source: UniProtKB
response to peptide hormone Source: UniProtKB
T cell receptor signaling pathway
Source: UniProtKB
Inferred from direct assayⁱ
- 8626696
translational initiation
Source: UniProtKB
Inferred from direct assayⁱ
- 16289705

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Initiation factor
Biological process	Protein biosynthesis

Enzyme and pathway databases

Reactomeⁱ	R-HSA-72731 Recycling of eIF2:GDP
SIGNORⁱ	P49770

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Translation initiation factor eIF-2B subunit beta Alternative name(s): S20I15 S20III15 eIF-2B GDP-GTP exchange factor subunit beta
Gene namesⁱ	Name:EIF2B2 Synonyms:EIF2BB
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 14

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000119718.10
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:3258 EIF2B2
MIMⁱ	606454 gene
neXtProtⁱ	NX_P49770

Subcellular locationⁱ

GO - Cellular component

Pathology & Biotechⁱ

Involvement in diseaseⁱ

Leukodystrophy with vanishing white matter (VWM)6 Publications

The disease is caused by mutations affecting the gene represented in this entry.

Disease descriptionA leukodystrophy that occurs mainly in children. Neurological signs include progressive cerebellar ataxia, spasticity, inconstant optic atrophy and relatively preserved mental abilities. The disease is chronic-progressive with, in most individuals, additional episodes of rapid deterioration following febrile infections or minor head trauma. While childhood onset is the most common form of the disorder, some severe forms are apparent at birth. A severe, early-onset form seen among the Cree and Chippewayan populations of Quebec and Manitoba is called Cree leukoencephalopathy. Milder forms may not become evident until adolescence or adulthood. Some females with milder forms of the disease who survive to adolescence exhibit ovarian dysfunction. This variant of the disorder is called ovarioleukodystrophy.

Keywords - Diseaseⁱ

Disease mutation, Leukodystrophy

Organism-specific databases

DisGeNET More...DisGeNETⁱ	8892
GeneReviewsⁱ	EIF2B2
MalaCards human disease database More...MalaCardsⁱ	EIF2B2
MIMⁱ	603896 phenotype
Open Targets More...OpenTargetsⁱ	ENSG00000119718
Orphanetⁱ	157713 Congenital or early infantile CACH syndrome 99854 Cree leukoencephalopathy 157719 Juvenile or adult CACH syndrome 157716 Late infantile CACH syndrome 99853 Ovarioleukodystrophy
PharmGKBⁱ	PA27689

Polymorphism and mutation databases

BioMutaⁱ	EIF2B2
DMDMⁱ	6226858

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000156061	1 – 351	Translation initiation factor eIF-2B subunit betaAdd BLAST		351

Proteomic databases

EPDⁱ	P49770
PaxDbⁱ	P49770
PeptideAtlas More...PeptideAtlasⁱ	P49770
PRIDEⁱ	P49770
ProteomicsDBⁱ	56113

PTM databases

iPTMnetⁱ	P49770
PhosphoSitePlusⁱ	P49770

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000119718 Expressed in 233 organ(s), highest expression level in right lobe of thyroid gland
CleanExⁱ	HS_EIF2B2
ExpressionAtlasⁱ	P49770 baseline and differential
Genevisibleⁱ	P49770 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	CAB037105 HPA005841 HPA048028

HPAⁱ

CAB037105
HPA005841
HPA048028

Interactionⁱ

Subunit structureⁱ

Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
C9orf72	Q96LT7	3	EBI-718773,EBI-2961725
EIF2B4	Q9UI10	5	EBI-718773,EBI-2340132

Protein-protein interaction databases

BioGridⁱ	114409, 78 interactors
IntActⁱ	P49770, 15 interactors
Molecular INTeraction database More...MINTⁱ	P49770
STRINGⁱ	9606.ENSP00000266126

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Helixⁱ	9 – 24	Combined sources	16
Beta strandⁱ	28 – 30	Combined sources	3
Helixⁱ	31 – 47	Combined sources	17
Helixⁱ	54 – 71	Combined sources	18
Helixⁱ	76 – 95	Combined sources	20
Helixⁱ	127 – 145	Combined sources	19
Helixⁱ	147 – 153	Combined sources	7
Helixⁱ	154 – 158	Combined sources	5
Beta strandⁱ	164 – 169	Combined sources	6
Helixⁱ	172 – 181	Combined sources	10
Turnⁱ	182 – 184	Combined sources	3
Beta strandⁱ	188 – 192	Combined sources	5
Turnⁱ	195 – 198	Combined sources	4
Helixⁱ	200 – 208	Combined sources	9
Beta strandⁱ	214 – 217	Combined sources	4
Helixⁱ	219 – 221	Combined sources	3
Helixⁱ	222 – 225	Combined sources	4
Helixⁱ	226 – 228	Combined sources	3
Beta strandⁱ	231 – 234	Combined sources	4
Beta strandⁱ	237 – 239	Combined sources	3
Beta strandⁱ	245 – 248	Combined sources	4
Helixⁱ	251 – 260	Combined sources	10
Beta strandⁱ	265 – 268	Combined sources	4
Turnⁱ	279 – 281	Combined sources	3
Turnⁱ	291 – 294	Combined sources	4
Helixⁱ	297 – 299	Combined sources	3
Helixⁱ	301 – 303	Combined sources	3
Beta strandⁱ	311 – 316	Combined sources	6
Helixⁱ	318 – 320	Combined sources	3
Beta strandⁱ	323 – 326	Combined sources	4
Beta strandⁱ	329 – 331	Combined sources	3
Helixⁱ	333 – 335	Combined sources	3
Helixⁱ	336 – 343	Combined sources	8
Helixⁱ	346 – 348	Combined sources	3

Show more details

3D structure databases

ProteinModelPortalⁱ	P49770
SMRⁱ	P49770
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the eIF-2B alpha/beta/delta subunits family.Curated

Phylogenomic databases

eggNOGⁱ	KOG1465 Eukaryota COG1184 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00550000074908
HOGENOMⁱ	HOG000208487
HOVERGENⁱ	HBG051458
InParanoidⁱ	P49770
KEGG Orthology (KO) More...KOⁱ	K03754
OMAⁱ	DHRWSNA
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G09RO
PhylomeDBⁱ	P49770
TreeFamⁱ	TF101506

Family and domain databases

InterProⁱ	View protein in InterPro IPR000649 IF-2B-related IPR037171 NagB/RpiA_transferase-like
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01008 IF-2B, 1 hit
SUPFAMⁱ	SSF100950 SSF100950, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show all Align All

P49770-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPGSAAKGSE LSERIESFVE TLKRGGGPRS SEEMARETLG LLRQIITDHR 
        60         70         80         90        100
WSNAGELMEL IRREGRRMTA AQPSETTVGN MVRRVLKIIR EEYGRLHGRS 
       110        120        130        140        150
DESDQQESLH KLLTSGGLNE DFSFHYAQLQ SNIIEAINEL LVELEGTMEN 
       160        170        180        190        200
IAAQALEHIH SNEVIMTIGF SRTVEAFLKE AARKRKFHVI VAECAPFCQG 
       210        220        230        240        250
HEMAVNLSKA GIETTVMTDA AIFAVMSRVN KVIIGTKTIL ANGALRAVTG 
       260        270        280        290        300
THTLALAAKH HSTPLIVCAP MFKLSPQFPN EEDSFHKFVA PEEVLPFTEG 
       310        320        330        340        350
DILEKVSVHC PVFDYVPPEL ITLFISNIGG NAPSYIYRLM SELYHPDDHV 

L

Length:351

Mass (Da):38,990

Last modified:May 30, 2000 - v3

Checksum:ⁱC29FE477143F545A

GO

Computationally mapped potential isoform sequencesⁱ

There are 3 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

H0YJJ8	H0YJJ8_HUMAN	Translation initiation factor eIF-2... Translation initiation factor eIF-2B subunit beta	EIF2B2	200	Annotation score:
G3V5E5	G3V5E5_HUMAN	Translation initiation factor eIF-2... Translation initiation factor eIF-2B subunit beta	EIF2B2	206	Annotation score:
H0YK01	H0YK01_HUMAN	Translation initiation factor eIF-2... Translation initiation factor eIF-2B subunit beta	EIF2B2	71	Annotation score:

Sequence cautionⁱ

The sequence AAC42002 differs from that shown. Reason: Frameshift at several positions.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	6	A → K in AAC42002 (PubMed:7596406).Curated	1
Sequence conflictⁱ	23	K → T in AAC42002 (PubMed:7596406).Curated	1
Sequence conflictⁱ	30	S → R in AAC42002 (PubMed:7596406).Curated	1
Sequence conflictⁱ	35	A → V in AAC42002 (PubMed:7596406).Curated	1
Sequence conflictⁱ	52	S → R in AAC42002 (PubMed:7596406).Curated	1
Sequence conflictⁱ	95 – 101	RLHGRSD → DSMDAAT in AAC42002 (PubMed:7596406).Curated	7
Sequence conflictⁱ	110	H → D in AAC42002 (PubMed:7596406).Curated	1

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_068451	85	V → E in VWM. 1 PublicationCorresponds to variant dbSNP:rs397514648EnsemblClinVar.	1
Natural variantⁱVAR_079034	127	A → V Found in a patient with Rett syndrome-like phenotype; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs150617429EnsemblClinVar.	1
Natural variantⁱVAR_016842	171	S → F in VWM; with ovarian failure. 2 PublicationsCorresponds to variant dbSNP:rs104894428EnsemblClinVar.	1
Natural variantⁱVAR_068452	196	P → S in VWM. 1 PublicationCorresponds to variant dbSNP:rs113994011Ensembl.	1
Natural variantⁱVAR_068453	200	G → V in VWM. 1 PublicationCorresponds to variant dbSNP:rs113994012EnsemblClinVar.	1
Natural variantⁱVAR_012289	213	E → G in VWM; with and without ovarian failure. 4 PublicationsCorresponds to variant dbSNP:rs104894425EnsemblClinVar.	1
Natural variantⁱVAR_068454	268	C → Y in VWM. 1 Publication	1
Natural variantⁱVAR_012321	273	K → R in VWM. 1 PublicationCorresponds to variant dbSNP:rs113994016EnsemblClinVar.	1
Natural variantⁱVAR_012290	316	V → D in VWM. 1 PublicationCorresponds to variant dbSNP:rs104894426EnsemblClinVar.	1
Natural variantⁱVAR_012322	329	G → V in VWM. 1 PublicationCorresponds to variant dbSNP:rs113994020Ensembl.	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF035280 mRNA Translation: AAB88176.1 L40395 mRNA Translation: AAC42002.1 Frameshift. AC006530 Genomic DNA Translation: AAD30183.1 BC011750 mRNA Translation: AAH11750.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS9836.1
NCBI Reference Sequences More...RefSeqⁱ	NP_055054.1, NM_014239.3
UniGeneⁱ	Hs.409137

Genome annotation databases

Ensemblⁱ	ENST00000266126; ENSP00000266126; ENSG00000119718
GeneIDⁱ	8892
KEGGⁱ	hsa:8892

Protein	Similar proteins		Species	Score	Length	Source
P49770	Eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa		HUMAN		351	UniRef100_P49770

Protein	Similar proteins		Species	Score	Length	Source
P49770	Translation initiation factor eIF-2B subunit beta		BOVIN		351	UniRef90_P49770
Translation initiation factor eIF-2B subunit beta		MOUSE		351
Translation initiation factor eIF-2B subunit beta		RABIT		351
Translation initiation factor eIF-2B subunit beta		RAT		351
Eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa		HUMAN		351
+110

Protein	Similar proteins		Species	Score	Length	Source
P49770	Translation initiation factor eIF-2B subunit beta		BOVIN		351	UniRef50_P49770
Translation initiation factor eIF-2B subunit beta		RABIT		351
Translation initiation factor eIF-2B subunit beta		RAT		351
Translation initiation factor eIF-2B subunit beta		MOUSE		351
Translation initiation factor eIF-2B subunit beta		TAKRU		355
+246

Cross-referencesⁱ

Web resourcesⁱ

Mendelian genes eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa (EIF2B2)

Leiden Open Variation Database (LOVD)

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF035280 mRNA Translation: AAB88176.1 L40395 mRNA Translation: AAC42002.1 Frameshift. AC006530 Genomic DNA Translation: AAD30183.1 BC011750 mRNA Translation: AAH11750.1
CCDSⁱ	CCDS9836.1
RefSeqⁱ	NP_055054.1, NM_014239.3
UniGeneⁱ	Hs.409137

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	6CAJ	electron microscopy	2.80	C/D	2-351	[»]
	6EZO	electron microscopy	4.10	C/D	5-351	[»]
ProteinModelPortalⁱ	P49770
SMRⁱ	P49770
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	114409, 78 interactors
IntActⁱ	P49770, 15 interactors
MINTⁱ	P49770
STRINGⁱ	9606.ENSP00000266126

PTM databases

iPTMnetⁱ	P49770
PhosphoSitePlusⁱ	P49770

Polymorphism and mutation databases

BioMutaⁱ	EIF2B2
DMDMⁱ	6226858

Proteomic databases

EPDⁱ	P49770
PaxDbⁱ	P49770
PeptideAtlasⁱ	P49770
PRIDEⁱ	P49770
ProteomicsDBⁱ	56113

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	8892
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000266126; ENSP00000266126; ENSG00000119718
GeneIDⁱ	8892
KEGGⁱ	hsa:8892

Organism-specific databases

CTDⁱ	8892
DisGeNETⁱ	8892
EuPathDBⁱ	HostDB:ENSG00000119718.10
GeneCardsⁱ	EIF2B2
GeneReviewsⁱ	EIF2B2
HGNCⁱ	HGNC:3258 EIF2B2
HPAⁱ	CAB037105 HPA005841 HPA048028
MalaCardsⁱ	EIF2B2
MIMⁱ	603896 phenotype 606454 gene
neXtProtⁱ	NX_P49770
OpenTargetsⁱ	ENSG00000119718
Orphanetⁱ	157713 Congenital or early infantile CACH syndrome 99854 Cree leukoencephalopathy 157719 Juvenile or adult CACH syndrome 157716 Late infantile CACH syndrome 99853 Ovarioleukodystrophy
PharmGKBⁱ	PA27689
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1465 Eukaryota COG1184 LUCA
GeneTreeⁱ	ENSGT00550000074908
HOGENOMⁱ	HOG000208487
HOVERGENⁱ	HBG051458
InParanoidⁱ	P49770
KOⁱ	K03754
OMAⁱ	DHRWSNA
OrthoDBⁱ	EOG091G09RO
PhylomeDBⁱ	P49770
TreeFamⁱ	TF101506

Enzyme and pathway databases

Reactomeⁱ	R-HSA-72731 Recycling of eIF2:GDP
SIGNORⁱ	P49770

Miscellaneous databases

ChiTaRSⁱ	EIF2B2 human
GeneWikiⁱ	EIF2B2
GenomeRNAiⁱ	8892
Protein Ontology More...PROⁱ	PR:P49770
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000119718 Expressed in 233 organ(s), highest expression level in right lobe of thyroid gland
CleanExⁱ	HS_EIF2B2
ExpressionAtlasⁱ	P49770 baseline and differential
Genevisibleⁱ	P49770 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR000649 IF-2B-related IPR037171 NagB/RpiA_transferase-like
Pfamⁱ	View protein in Pfam PF01008 IF-2B, 1 hit
SUPFAMⁱ	SSF100950 SSF100950, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	EI2BB_HUMAN
Accessionⁱ	P49770Primary (citable) accession number: P49770 Secondary accession number(s): O43201
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
	Last sequence update:	May 30, 2000
	Last modified:	November 7, 2018
	This is version 164 of the entry and version 3 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
PDB cross-references
Index of Protein Data Bank (PDB) cross-references
Human chromosome 14
Human chromosome 14: entries, gene names and cross-references to MIM

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UniProtKB - P49770 (EI2BB_HUMAN)

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Translation initiation factor eIF-2B subunit beta

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

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Other locations

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Keywords - Diseasei

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Natural variant

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

Keywords - Diseaseⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequence cautionⁱ

Cross-referencesⁱ

Web resourcesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ