TUFM

Functionⁱ

Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG-I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy.2 Publications

Regions

Feature key	Position(s)	DescriptionActions	Length
Nucleotide bindingⁱ	64 – 71	GTPBy similarity	8
Nucleotide bindingⁱ	126 – 130	GTPBy similarity	5
Nucleotide bindingⁱ	181 – 184	GTPBy similarity	4

GO - Molecular functionⁱ

GTPase activity Source: InterPro
GTP binding Source: UniProtKB-KW
RNA binding
Source: UniProtKB
Inferred from high throughput direct assayⁱ
- 22658674
translation elongation factor activity
Source: UniProtKB
Inferred from direct assayⁱ
- 9332382

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

mitochondrial translational elongation
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
response to ethanol Source: Ensembl
translational elongation
Source: UniProtKB
Inferred from direct assayⁱ
- 9332382

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Elongation factor
Biological process	Protein biosynthesis
Ligand	GTP-binding, Nucleotide-binding

Enzyme and pathway databases

Reactomeⁱ	R-HSA-5389840 Mitochondrial translation elongation
SignaLinkⁱ	P49411

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Elongation factor Tu, mitochondrial Short name: EF-Tu Alternative name(s): P43
Gene namesⁱ	Name:TUFM
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 16

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000178952.8
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:12420 TUFM
MIMⁱ	602389 gene
neXtProtⁱ	NX_P49411

Keywords - Cellular componentⁱ

Mitochondrion

Pathology & Biotechⁱ

Involvement in diseaseⁱ

Combined oxidative phosphorylation deficiency 4 (COXPD4)1 Publication

The disease is caused by mutations affecting the gene represented in this entry.

Disease descriptionA mitochondrial disease resulting in neonatal lactic acidosis, rapidly progressive encephalopathy, severely decreased mitochondrial protein synthesis, and combined deficiency of mtDNA-related mitochondrial respiratory chain complexes.

Keywords - Diseaseⁱ

Disease mutation, Primary mitochondrial disease

Organism-specific databases

DisGeNET More...DisGeNETⁱ	7284
MalaCards human disease database More...MalaCardsⁱ	TUFM
MIMⁱ	610678 phenotype
Orphanetⁱ	254925 Combined oxidative phosphorylation defect type 4
PharmGKBⁱ	PA37082

Chemistry databases

Drug and drug target database More...DrugBankⁱ	DB04315 Guanosine-5'-Diphosphate

DrugBankⁱ

DB04315 Guanosine-5'-Diphosphate

Polymorphism and mutation databases

BioMutaⁱ	TUFM
DMDMⁱ	1706611

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transit peptideⁱ	1 – 43	Mitochondrion2 PublicationsAdd BLAST		43
ChainⁱPRO_0000007462	44 – 452	Elongation factor Tu, mitochondrialAdd BLAST		409

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	79	N6-acetyllysineCombined sources	1
Modified residueⁱ	88	N6-acetyllysine; alternateCombined sources	1
Modified residueⁱ	88	N6-succinyllysine; alternateBy similarity	1
Modified residueⁱ	234	N6-succinyllysineBy similarity	1
Modified residueⁱ	256	N6-acetyllysineCombined sources	1
Modified residueⁱ	278	PhosphothreonineCombined sources	1
Modified residueⁱ	286	N6-succinyllysineBy similarity	1
Modified residueⁱ	312	PhosphoserineBy similarity	1
Modified residueⁱ	361	N6-acetyllysineBy similarity	1
Modified residueⁱ	418	N6-acetyllysineCombined sources	1

Keywords - PTMⁱ

Acetylation, Phosphoprotein

Proteomic databases

EPDⁱ	P49411
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P49411
PaxDbⁱ	P49411
PeptideAtlas More...PeptideAtlasⁱ	P49411
PRIDEⁱ	P49411
ProteomicsDBⁱ	56003
TopDownProteomicsⁱ	P49411

2D gel databases

DOSAC-COBS 2D-PAGE database More...DOSAC-COBS-2DPAGEⁱ	P49411
USC-OGP 2-DE database More...OGPⁱ	P49411
REPRODUCTION-2DPAGE More...REPRODUCTION-2DPAGEⁱ	IPI00027107
SWISS-2DPAGEⁱ	P49411
UCD-2DPAGEⁱ	P49411

PTM databases

CarbonylDBⁱ	P49411
iPTMnetⁱ	P49411
PhosphoSitePlusⁱ	P49411
SwissPalmⁱ	P49411

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000178952 Expressed in 122 organ(s), highest expression level in testis
CleanExⁱ	HS_TUFM
ExpressionAtlasⁱ	P49411 baseline and differential
Genevisibleⁱ	P49411 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	CAB075730 CAB075731 HPA018991 HPA024087

HPAⁱ

CAB075730
CAB075731
HPA018991
HPA024087

Interactionⁱ

Subunit structureⁱ

(Microbial infection) Interacts with human parainfluenza virus 3 matrix protein; this interaction inhibits RLR-mediated type I interferon production while promoting autophagy.1 Publication

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
ARL6IP1	Q15041	3	EBI-359097,EBI-714543
CMTM5	Q96DZ9	3	EBI-359097,EBI-2548702
FAM9B	Q8IZU0	3	EBI-359097,EBI-10175124
FUNDC1	Q8IVP5	3	EBI-359097,EBI-3059266
NLRX1	Q86UT6	2	EBI-359097,EBI-3893071
PB2	P03427	9	EBI-359097,EBI-8430745	From Influenza A virus (strain A/Wilson-Smith/1933 H1N1).

Protein-protein interaction databases

BioGridⁱ	113135, 180 interactors
CORUMⁱ	P49411
IntActⁱ	P49411, 49 interactors
Molecular INTeraction database More...MINTⁱ	P49411
STRINGⁱ	9606.ENSP00000322439

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P49411
SMRⁱ	P49411
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	55 – 251	tr-type GPROSITE-ProRule annotationAdd BLAST		197

Region

Feature key	Position(s)	DescriptionActions	Length
Regionⁱ	64 – 71	G1PROSITE-ProRule annotation	8
Regionⁱ	105 – 109	G2PROSITE-ProRule annotation	5
Regionⁱ	126 – 129	G3PROSITE-ProRule annotation	4
Regionⁱ	181 – 184	G4PROSITE-ProRule annotation	4
Regionⁱ	219 – 221	G5PROSITE-ProRule annotation	3

Sequence similaritiesⁱ

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.PROSITE-ProRule annotation

Keywords - Domainⁱ

Transit peptide

Phylogenomic databases

eggNOGⁱ	KOG0460 Eukaryota COG0050 LUCA
HOGENOMⁱ	HOG000229290
HOVERGENⁱ	HBG001535
InParanoidⁱ	P49411
KEGG Orthology (KO) More...KOⁱ	K02358
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0BFD
PhylomeDBⁱ	P49411
TreeFamⁱ	TF300432

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd03697 EFTU_II, 1 hit
InterProⁱ	View protein in InterPro IPR004161 EFTu-like_2 IPR033720 EFTU_2 IPR031157 G_TR_CS IPR027417 P-loop_NTPase IPR000795 TF_GTP-bd_dom IPR009000 Transl_B-barrel_sf IPR009001 Transl_elong_EF1A/Init_IF2_C IPR004541 Transl_elong_EFTu/EF1A_bac/org IPR004160 Transl_elong_EFTu/EF1A_C
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00009 GTP_EFTU, 1 hit PF03144 GTP_EFTU_D2, 1 hit PF03143 GTP_EFTU_D3, 1 hit
PRINTSⁱ	PR00315 ELONGATNFCT
SUPFAMⁱ	SSF50447 SSF50447, 1 hit SSF50465 SSF50465, 1 hit SSF52540 SSF52540, 1 hit
TIGRFAMsⁱ	TIGR00485 EF-Tu, 1 hit
PROSITEⁱ	View protein in PROSITE PS00301 G_TR_1, 1 hit PS51722 G_TR_2, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show all Align All

P49411-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAAATLLRAT PHFSGLAAGR TFLLQGLLRL LKAPALPLLC RGLAVEAKKT 
        60         70         80         90        100
YVRDKPHVNV GTIGHVDHGK TTLTAAITKI LAEGGGAKFK KYEEIDNAPE 
       110        120        130        140        150
ERARGITINA AHVEYSTAAR HYAHTDCPGH ADYVKNMITG TAPLDGCILV 
       160        170        180        190        200
VAANDGPMPQ TREHLLLARQ IGVEHVVVYV NKADAVQDSE MVELVELEIR 
       210        220        230        240        250
ELLTEFGYKG EETPVIVGSA LCALEGRDPE LGLKSVQKLL DAVDTYIPVP 
       260        270        280        290        300
ARDLEKPFLL PVEAVYSVPG RGTVVTGTLE RGILKKGDEC ELLGHSKNIR 
       310        320        330        340        350
TVVTGIEMFH KSLERAEAGD NLGALVRGLK REDLRRGLVM VKPGSIKPHQ 
       360        370        380        390        400
KVEAQVYILS KEEGGRHKPF VSHFMPVMFS LTWDMACRII LPPEKELAMP 
       410        420        430        440        450
GEDLKFNLIL RQPMILEKGQ RFTLRDGNRT IGTGLVTNTL AMTEEEKNIK 

WG

Length:452

Mass (Da):49,542

Last modified:October 1, 1996 - v2

Checksum:ⁱE37274ABFFDB5FC7

GO

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	H3BNU3	H3BNU3_HUMAN		Elongation factor Tu, mitochondrial Elongation factor Tu, mitochondrial	TUFM	101	Annotation score:

Sequence cautionⁱ

The sequence AAC60647 differs from that shown. Reason: Erroneous initiation.Curated

The sequence AAH01633 differs from that shown. Reason: Erroneous initiation.Curated

The sequence AAH10041 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	195 – 197	Missing in AAC60647 (PubMed:7828719).Curated	3
Sequence conflictⁱ	384	D → N in AAB00499 (PubMed:8547323).Curated	1
Sequence conflictⁱ	384	D → N in CAA72493 (Ref. 9) Curated	1

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_031902	336	R → Q in COXPD4. 1 Publication		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	L38995 mRNA Translation: AAB00499.1 S75463 mRNA Translation: AAC60647.1 Different initiation. X84694 mRNA Translation: CAA59169.1 AC133550 Genomic DNA No translation available. BC001633 mRNA Translation: AAH01633.2 Different initiation. BC010041 mRNA Translation: AAH10041.2 Different initiation. Y11797 Genomic DNA Translation: CAA72493.1
PIRⁱ	S62767 S68466
NCBI Reference Sequences More...RefSeqⁱ	NP_003312.3, NM_003321.4 XP_016879108.1, XM_017023619.1
UniGeneⁱ	Hs.12084

Genome annotation databases

Ensemblⁱ	ENST00000313511; ENSP00000322439; ENSG00000178952
GeneIDⁱ	7284
KEGGⁱ	hsa:7284
UCSC genome browser More...UCSCⁱ	uc002drh.2 human

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P49411	Elongation factor Tu		PANTR		455	UniRef100_P49411

Protein	Similar proteins		Species	Score	Length	Source
P49411	Elongation factor Tu		PANTR		455	UniRef90_P49411
Elongation factor Tu		CRIGR		458
Elongation factor Tu		MACMU		455
Elongation factor Tu		MACNE		455
Elongation factor Tu		PONAB		455
+43

Protein	Similar proteins		Species	Score	Length	Source
P49411	Elongation factor Tu, mitochondrial		MOUSE		452	UniRef50_P49411
Elongation factor Tu, mitochondrial		RAT		452
Elongation factor Tu, chloroplastic		SOYBN		479
Elongation factor TuA, chloroplastic		NICSY		478
Elongation factor Tu, chloroplastic		TOBAC		478
+771

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	L38995 mRNA Translation: AAB00499.1 S75463 mRNA Translation: AAC60647.1 Different initiation. X84694 mRNA Translation: CAA59169.1 AC133550 Genomic DNA No translation available. BC001633 mRNA Translation: AAH01633.2 Different initiation. BC010041 mRNA Translation: AAH10041.2 Different initiation. Y11797 Genomic DNA Translation: CAA72493.1
PIRⁱ	S62767 S68466
RefSeqⁱ	NP_003312.3, NM_003321.4 XP_016879108.1, XM_017023619.1
UniGeneⁱ	Hs.12084

3D structure databases

ProteinModelPortalⁱ	P49411
SMRⁱ	P49411
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	113135, 180 interactors
CORUMⁱ	P49411
IntActⁱ	P49411, 49 interactors
MINTⁱ	P49411
STRINGⁱ	9606.ENSP00000322439

Chemistry databases

DrugBankⁱ	DB04315 Guanosine-5'-Diphosphate

DrugBankⁱ

DB04315 Guanosine-5'-Diphosphate

PTM databases

CarbonylDBⁱ	P49411
iPTMnetⁱ	P49411
PhosphoSitePlusⁱ	P49411
SwissPalmⁱ	P49411

Polymorphism and mutation databases

BioMutaⁱ	TUFM
DMDMⁱ	1706611

2D gel databases

DOSAC-COBS-2DPAGEⁱ	P49411
OGPⁱ	P49411
REPRODUCTION-2DPAGEⁱ	IPI00027107
SWISS-2DPAGEⁱ	P49411
UCD-2DPAGEⁱ	P49411

Proteomic databases

EPDⁱ	P49411
MaxQBⁱ	P49411
PaxDbⁱ	P49411
PeptideAtlasⁱ	P49411
PRIDEⁱ	P49411
ProteomicsDBⁱ	56003
TopDownProteomicsⁱ	P49411

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	7284
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000313511; ENSP00000322439; ENSG00000178952
GeneIDⁱ	7284
KEGGⁱ	hsa:7284
UCSCⁱ	uc002drh.2 human

Organism-specific databases

CTDⁱ	7284
DisGeNETⁱ	7284
EuPathDBⁱ	HostDB:ENSG00000178952.8
GeneCardsⁱ	TUFM
HGNCⁱ	HGNC:12420 TUFM
HPAⁱ	CAB075730 CAB075731 HPA018991 HPA024087
MalaCardsⁱ	TUFM
MIMⁱ	602389 gene 610678 phenotype
neXtProtⁱ	NX_P49411
Orphanetⁱ	254925 Combined oxidative phosphorylation defect type 4
PharmGKBⁱ	PA37082
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0460 Eukaryota COG0050 LUCA
HOGENOMⁱ	HOG000229290
HOVERGENⁱ	HBG001535
InParanoidⁱ	P49411
KOⁱ	K02358
OrthoDBⁱ	EOG091G0BFD
PhylomeDBⁱ	P49411
TreeFamⁱ	TF300432

Enzyme and pathway databases

Reactomeⁱ	R-HSA-5389840 Mitochondrial translation elongation
SignaLinkⁱ	P49411

Miscellaneous databases

ChiTaRSⁱ	TUFM human
GeneWikiⁱ	TUFM
GenomeRNAiⁱ	7284
Protein Ontology More...PROⁱ	PR:P49411
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000178952 Expressed in 122 organ(s), highest expression level in testis
CleanExⁱ	HS_TUFM
ExpressionAtlasⁱ	P49411 baseline and differential
Genevisibleⁱ	P49411 HS

Family and domain databases

CDDⁱ	cd03697 EFTU_II, 1 hit
InterProⁱ	View protein in InterPro IPR004161 EFTu-like_2 IPR033720 EFTU_2 IPR031157 G_TR_CS IPR027417 P-loop_NTPase IPR000795 TF_GTP-bd_dom IPR009000 Transl_B-barrel_sf IPR009001 Transl_elong_EF1A/Init_IF2_C IPR004541 Transl_elong_EFTu/EF1A_bac/org IPR004160 Transl_elong_EFTu/EF1A_C
Pfamⁱ	View protein in Pfam PF00009 GTP_EFTU, 1 hit PF03144 GTP_EFTU_D2, 1 hit PF03143 GTP_EFTU_D3, 1 hit
PRINTSⁱ	PR00315 ELONGATNFCT
SUPFAMⁱ	SSF50447 SSF50447, 1 hit SSF50465 SSF50465, 1 hit SSF52540 SSF52540, 1 hit
TIGRFAMsⁱ	TIGR00485 EF-Tu, 1 hit
PROSITEⁱ	View protein in PROSITE PS00301 G_TR_1, 1 hit PS51722 G_TR_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	EFTU_HUMAN
Accessionⁱ	P49411Primary (citable) accession number: P49411 Secondary accession number(s): O15276
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
	Last sequence update:	October 1, 1996
	Last modified:	November 7, 2018
	This is version 200 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Direct protein sequencing, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human chromosome 16
Human chromosome 16: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

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Supporting data

UniProtKB - P49411 (EFTU_HUMAN)

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Elongation factor Tu, mitochondrial

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Mitochondrion

Extracellular region or secreted

Mitochondrion

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Keywords - Diseasei

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

2D gel databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Natural variant

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

PTM databases

Polymorphism and mutation databases

2D gel databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

Keywords - Diseaseⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ