The new UniProt website is here!
Take me to UniProt BETA
UniProtKB - P49228 (RL32_DEIRA)
Protein
50S ribosomal protein L32
Gene
rpmF
Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Status
Functioni
Forms a cluster with L17 and L22, and with L22, a pair of 'tweezers' that hold together all the domains of the 23S rRNA. Interacts with the antibiotic troleandomycin which blocks the peptide exit tunnel.
Cofactori
Zn2+CuratedNote: Binds 1 zinc ion per subunit.Curated
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 33 | ZincCurated | 1 | |
Metal bindingi | 36 | ZincCurated | 1 | |
Metal bindingi | 46 | ZincCurated | 1 | |
Metal bindingi | 49 | ZincCurated | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 33 – 49 | C4-typeCuratedAdd BLAST | 17 |
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
- rRNA binding Source: UniProtKB-KW
- structural constituent of ribosome Source: GO_Central
GO - Biological processi
- translation Source: UniProtKB-UniRule
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: 50S ribosomal protein L32 |
Gene namesi | Name:rpmF Ordered Locus Names:DR_2366 |
Organismi | Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422) |
Taxonomic identifieri | 243230 [NCBI] |
Taxonomic lineagei | Bacteria › Deinococcus-Thermus › Deinococci › Deinococcales › Deinococcaceae › Deinococcus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | Removed | |||
ChainiPRO_0000172336 | 2 – 60 | 50S ribosomal protein L32Add BLAST | 59 |
Interactioni
Subunit structurei
Part of the 50S ribosomal subunit. Contacts proteins L17 and L22.
6 PublicationsProtein-protein interaction databases
IntActi | P49228, 1 interactor |
STRINGi | 243230.DR_2366 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
AlphaFoldDBi | P49228 |
SMRi | P49228 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P49228 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 34 | DisorderedSequence analysisAdd BLAST | 34 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 20 | Basic residuesSequence analysisAdd BLAST | 20 |
Sequence similaritiesi
Belongs to the bacterial ribosomal protein bL32 family.Curated
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 33 – 49 | C4-typeCuratedAdd BLAST | 17 |
Keywords - Domaini
Zinc-fingerPhylogenomic databases
eggNOGi | COG0333, Bacteria |
HOGENOMi | CLU_129084_1_3_0 |
InParanoidi | P49228 |
OMAi | HRACRHC |
OrthoDBi | 2092354at2 |
Family and domain databases
HAMAPi | MF_00340, Ribosomal_L32, 1 hit |
InterProi | View protein in InterPro IPR002677, Ribosomal_L32p IPR044957, Ribosomal_L32p_bact IPR011332, Ribosomal_zn-bd |
PANTHERi | PTHR35534, PTHR35534, 1 hit |
Pfami | View protein in Pfam PF01783, Ribosomal_L32p, 1 hit |
SUPFAMi | SSF57829, SSF57829, 1 hit |
TIGRFAMsi | TIGR01031, rpmF_bact, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P49228-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAKHPVPKKK TSKSKRDMRR SHHALTAPNL TECPQCHGKK LSHHICPNCG
60
YYDGRQVLAV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D63900 Genomic DNA Translation: BAA09939.1 AE000513 Genomic DNA Translation: AAF11913.1 |
PIRi | F75282 |
RefSeqi | NP_296087.1, NC_001263.1 WP_010888992.1, NZ_CP015081.1 |
Genome annotation databases
EnsemblBacteriai | AAF11913; AAF11913; DR_2366 |
KEGGi | dra:DR_2366 |
PATRICi | fig|243230.17.peg.2600 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D63900 Genomic DNA Translation: BAA09939.1 AE000513 Genomic DNA Translation: AAF11913.1 |
PIRi | F75282 |
RefSeqi | NP_296087.1, NC_001263.1 WP_010888992.1, NZ_CP015081.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1J5A | X-ray | 3.50 | M | 1-60 | [»] | |
1JZX | X-ray | 3.10 | M | 1-60 | [»] | |
1JZY | X-ray | 3.50 | M | 1-60 | [»] | |
1JZZ | X-ray | 3.80 | M | 1-60 | [»] | |
1K01 | X-ray | 3.50 | M | 1-60 | [»] | |
1NKW | X-ray | 3.10 | Z | 1-60 | [»] | |
1NWX | X-ray | 3.50 | Z | 2-60 | [»] | |
1NWY | X-ray | 3.30 | Z | 2-60 | [»] | |
1OND | X-ray | 3.40 | Z | 1-60 | [»] | |
1SM1 | X-ray | 3.42 | Z | 1-60 | [»] | |
1XBP | X-ray | 3.50 | Z | 2-60 | [»] | |
2ZJP | X-ray | 3.70 | Y | 1-60 | [»] | |
2ZJQ | X-ray | 3.30 | Z | 1-60 | [»] | |
2ZJR | X-ray | 2.91 | Z | 1-60 | [»] | |
3CF5 | X-ray | 3.30 | Y | 1-60 | [»] | |
3DLL | X-ray | 3.50 | Y | 1-60 | [»] | |
3PIO | X-ray | 3.25 | Z | 1-60 | [»] | |
3PIP | X-ray | 3.45 | Z | 1-60 | [»] | |
4IO9 | X-ray | 3.20 | Z | 1-60 | [»] | |
4IOA | X-ray | 3.20 | Z | 1-60 | [»] | |
4IOC | X-ray | 3.60 | Z | 1-60 | [»] | |
4U67 | X-ray | 3.65 | Z | 1-60 | [»] | |
4V49 | X-ray | 8.70 | Z | 2-59 | [»] | |
4V4A | X-ray | 9.50 | Z | 2-59 | [»] | |
4V4G | X-ray | 11.50 | 2 | 2-59 | [»] | |
4V4R | X-ray | 5.90 | B5 | 1-60 | [»] | |
4V4S | X-ray | 6.76 | B5 | 1-60 | [»] | |
4V4T | X-ray | 6.46 | 5 | 1-60 | [»] | |
4WFN | X-ray | 3.54 | Z | 1-60 | [»] | |
5DM6 | X-ray | 2.90 | Z | 3-59 | [»] | |
5DM7 | X-ray | 3.00 | Z | 3-59 | [»] | |
5JVG | X-ray | 3.43 | Z | 1-60 | [»] | |
5JVH | X-ray | 3.58 | Z | 1-60 | [»] | |
7A0R | X-ray | 3.30 | Z | 2-59 | [»] | |
7A0S | X-ray | 3.22 | Z | 2-59 | [»] | |
7A18 | X-ray | 3.40 | Z | 3-59 | [»] | |
AlphaFoldDBi | P49228 | |||||
SMRi | P49228 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
IntActi | P49228, 1 interactor |
STRINGi | 243230.DR_2366 |
Chemistry databases
DrugBanki | DB13179, Troleandomycin |
Genome annotation databases
EnsemblBacteriai | AAF11913; AAF11913; DR_2366 |
KEGGi | dra:DR_2366 |
PATRICi | fig|243230.17.peg.2600 |
Phylogenomic databases
eggNOGi | COG0333, Bacteria |
HOGENOMi | CLU_129084_1_3_0 |
InParanoidi | P49228 |
OMAi | HRACRHC |
OrthoDBi | 2092354at2 |
Miscellaneous databases
EvolutionaryTracei | P49228 |
Family and domain databases
HAMAPi | MF_00340, Ribosomal_L32, 1 hit |
InterProi | View protein in InterPro IPR002677, Ribosomal_L32p IPR044957, Ribosomal_L32p_bact IPR011332, Ribosomal_zn-bd |
PANTHERi | PTHR35534, PTHR35534, 1 hit |
Pfami | View protein in Pfam PF01783, Ribosomal_L32p, 1 hit |
SUPFAMi | SSF57829, SSF57829, 1 hit |
TIGRFAMsi | TIGR01031, rpmF_bact, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | RL32_DEIRA | |
Accessioni | P49228Primary (citable) accession number: P49228 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 1, 1996 |
Last sequence update: | January 23, 2007 | |
Last modified: | May 25, 2022 | |
This is version 139 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Ribosomal proteins
Ribosomal proteins families and list of entries - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families