Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

60S ribosomal protein L34

Gene

RPL34

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the large ribosomal subunit.1 Publication3 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • cadherin binding Source: BHF-UCL
  • RNA binding Source: ProtInc
  • structural constituent of ribosome Source: ProtInc

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
60S ribosomal protein L34
Alternative name(s):
Large ribosomal subunit protein eL341 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPL34
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000109475.16

Human Gene Nomenclature Database

More...
HGNCi
HGNC:10340 RPL34

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
616862 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P49207

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
6164

Open Targets

More...
OpenTargetsi
ENSG00000109475

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34723

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RPL34

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved1 Publication
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001318312 – 11760S ribosomal protein L34Add BLAST116

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei12PhosphoserineCombined sources1
Modified residuei36N6-acetyllysineCombined sources1
Modified residuei43N6-acetyllysineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki108Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P49207

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P49207

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P49207

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P49207

PeptideAtlas

More...
PeptideAtlasi
P49207

PRoteomics IDEntifications database

More...
PRIDEi
P49207

ProteomicsDB human proteome resource

More...
ProteomicsDBi
55970

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P49207

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P49207

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P49207

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P49207

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000109475 Expressed in 111 organ(s), highest expression level in sigmoid colon

CleanEx database of gene expression profiles

More...
CleanExi
HS_RPL34

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P49207 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P49207 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA035139

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the large ribosomal subunit.1 Publication3 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
112083, 96 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
P49207

Protein interaction database and analysis system

More...
IntActi
P49207, 15 interactors

Molecular INTeraction database

More...
MINTi
P49207

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000378160

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4UG0electron microscopy-Lg1-117[»]
4V6Xelectron microscopy5.00Cg1-117[»]
5AJ0electron microscopy3.50Ag1-117[»]
5LKSelectron microscopy3.60Lg1-117[»]
5T2Celectron microscopy3.60a1-117[»]
6EK0electron microscopy2.90Lg1-117[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P49207

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P49207

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1790 Eukaryota
COG2174 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000008294

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000216922

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG024280

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P49207

KEGG Orthology (KO)

More...
KOi
K02915

Identification of Orthologs from Complete Genome Data

More...
OMAi
RCGDCVK

Database of Orthologous Groups

More...
OrthoDBi
1517591at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P49207

TreeFam database of animal gene trees

More...
TreeFami
TF314326

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.1800.40, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008195 Ribosomal_L34Ae
IPR038562 Ribosomal_L34Ae_sf
IPR018065 Ribosomal_L34e_CS

The PANTHER Classification System

More...
PANTHERi
PTHR10759 PTHR10759, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01199 Ribosomal_L34e, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01250 RIBOSOMALL34

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01145 RIBOSOMAL_L34E, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P49207-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVQRLTYRRR LSYNTASNKT RLSRTPGNRI VYLYTKKVGK APKSACGVCP
60 70 80 90 100
GRLRGVRAVR PKVLMRLSKT KKHVSRAYGG SMCAKCVRDR IKRAFLIEEQ
110
KIVVKVLKAQ AQSQKAK
Length:117
Mass (Da):13,293
Last modified:January 23, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFC09D00B98CB770C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti52R → K in AAC41916 (PubMed:7490091).Curated1
Sequence conflicti58A → P in AAC41916 (PubMed:7490091).Curated1
Sequence conflicti103V → I in AAC41916 (PubMed:7490091).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L38941 mRNA Translation: AAC41916.1
AB061832 Genomic DNA Translation: BAB79470.1
CR542232 mRNA Translation: CAG47028.1
CR542242 mRNA Translation: CAG47038.1
BC001773 mRNA Translation: AAH01773.1
BC070208 mRNA Translation: AAH70208.1
BC106009 mRNA Translation: AAI06010.1
AB007181 Genomic DNA Translation: BAA25840.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3680.1

Protein sequence database of the Protein Information Resource

More...
PIRi
I68524

NCBI Reference Sequences

More...
RefSeqi
NP_000986.2, NM_000995.4
NP_001306161.1, NM_001319232.1
NP_001306163.1, NM_001319234.1
NP_001306164.1, NM_001319235.1
NP_001306165.1, NM_001319236.1
NP_296374.1, NM_033625.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.438227

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000394665; ENSP00000378160; ENSG00000109475
ENST00000394667; ENSP00000378162; ENSG00000109475
ENST00000394668; ENSP00000378163; ENSG00000109475
ENST00000502534; ENSP00000423983; ENSG00000109475
ENST00000506397; ENSP00000423316; ENSG00000109475

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
6164

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:6164

UCSC genome browser

More...
UCSCi
uc003hza.4 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L38941 mRNA Translation: AAC41916.1
AB061832 Genomic DNA Translation: BAB79470.1
CR542232 mRNA Translation: CAG47028.1
CR542242 mRNA Translation: CAG47038.1
BC001773 mRNA Translation: AAH01773.1
BC070208 mRNA Translation: AAH70208.1
BC106009 mRNA Translation: AAI06010.1
AB007181 Genomic DNA Translation: BAA25840.1
CCDSiCCDS3680.1
PIRiI68524
RefSeqiNP_000986.2, NM_000995.4
NP_001306161.1, NM_001319232.1
NP_001306163.1, NM_001319234.1
NP_001306164.1, NM_001319235.1
NP_001306165.1, NM_001319236.1
NP_296374.1, NM_033625.3
UniGeneiHs.438227

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4UG0electron microscopy-Lg1-117[»]
4V6Xelectron microscopy5.00Cg1-117[»]
5AJ0electron microscopy3.50Ag1-117[»]
5LKSelectron microscopy3.60Lg1-117[»]
5T2Celectron microscopy3.60a1-117[»]
6EK0electron microscopy2.90Lg1-117[»]
ProteinModelPortaliP49207
SMRiP49207
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi112083, 96 interactors
CORUMiP49207
IntActiP49207, 15 interactors
MINTiP49207
STRINGi9606.ENSP00000378160

PTM databases

iPTMnetiP49207
PhosphoSitePlusiP49207
SwissPalmiP49207

Polymorphism and mutation databases

BioMutaiRPL34

Proteomic databases

EPDiP49207
jPOSTiP49207
MaxQBiP49207
PaxDbiP49207
PeptideAtlasiP49207
PRIDEiP49207
ProteomicsDBi55970
TopDownProteomicsiP49207

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
6164
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000394665; ENSP00000378160; ENSG00000109475
ENST00000394667; ENSP00000378162; ENSG00000109475
ENST00000394668; ENSP00000378163; ENSG00000109475
ENST00000502534; ENSP00000423983; ENSG00000109475
ENST00000506397; ENSP00000423316; ENSG00000109475
GeneIDi6164
KEGGihsa:6164
UCSCiuc003hza.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6164
DisGeNETi6164
EuPathDBiHostDB:ENSG00000109475.16

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RPL34

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0004432
HGNCiHGNC:10340 RPL34
HPAiHPA035139
MIMi616862 gene
neXtProtiNX_P49207
OpenTargetsiENSG00000109475
PharmGKBiPA34723

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1790 Eukaryota
COG2174 LUCA
GeneTreeiENSGT00390000008294
HOGENOMiHOG000216922
HOVERGENiHBG024280
InParanoidiP49207
KOiK02915
OMAiRCGDCVK
OrthoDBi1517591at2759
PhylomeDBiP49207
TreeFamiTF314326

Enzyme and pathway databases

ReactomeiR-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902 Peptide chain elongation
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2408557 Selenocysteine synthesis
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
RPL34 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
RPL34

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
6164

Protein Ontology

More...
PROi
PR:P49207

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000109475 Expressed in 111 organ(s), highest expression level in sigmoid colon
CleanExiHS_RPL34
ExpressionAtlasiP49207 baseline and differential
GenevisibleiP49207 HS

Family and domain databases

Gene3Di3.40.1800.40, 1 hit
InterProiView protein in InterPro
IPR008195 Ribosomal_L34Ae
IPR038562 Ribosomal_L34Ae_sf
IPR018065 Ribosomal_L34e_CS
PANTHERiPTHR10759 PTHR10759, 1 hit
PfamiView protein in Pfam
PF01199 Ribosomal_L34e, 1 hit
PRINTSiPR01250 RIBOSOMALL34
PROSITEiView protein in PROSITE
PS01145 RIBOSOMAL_L34E, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRL34_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P49207
Secondary accession number(s): Q6FG66, Q9BUZ2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: January 23, 2007
Last modified: January 16, 2019
This is version 171 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again