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Protein

40S ribosomal protein S12

Gene

rps-12

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-CEL-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-CEL-1799339 SRP-dependent cotranslational protein targeting to membrane
R-CEL-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-CEL-72689 Formation of a pool of free 40S subunits
R-CEL-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-CEL-72702 Ribosomal scanning and start codon recognition
R-CEL-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-CEL-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-CEL-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S12
Gene namesi
Name:rps-12
ORF Names:F54E7.2
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiF54E7.2 ; CE26896 ; WBGene00004481 ; rps-12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001223291 – 14040S ribosomal protein S12Add BLAST140

Proteomic databases

EPDiP49196
PaxDbiP49196
PeptideAtlasiP49196
PRIDEiP49196

2D gel databases

World-2DPAGEi0020:P49196

PTM databases

iPTMnetiP49196

Expressioni

Gene expression databases

BgeeiWBGene00004481

Interactioni

Protein-protein interaction databases

BioGridi41013, 4 interactors
IntActiP49196, 1 interactor
STRINGi6239.F54E7.2.2

Structurei

3D structure databases

ProteinModelPortaliP49196
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3406 Eukaryota
COG1358 LUCA
GeneTreeiENSGT00390000018318
HOGENOMiHOG000210688
InParanoidiP49196
KOiK02951
OMAiGLRECAK
OrthoDBiEOG091G0UB5
PhylomeDBiP49196

Family and domain databases

Gene3Di3.30.1330.30, 1 hit
InterProiView protein in InterPro
IPR029064 L30e-like
IPR004038 Ribosomal_L7Ae/L30e/S12e/Gad45
IPR000530 Ribosomal_S12e
PANTHERiPTHR11843 PTHR11843, 1 hit
PfamiView protein in Pfam
PF01248 Ribosomal_L7Ae, 1 hit
PRINTSiPR00972 RIBSOMALS12E
SUPFAMiSSF55315 SSF55315, 1 hit
PROSITEiView protein in PROSITE
PS01189 RIBOSOMAL_S12E, 1 hit

Sequencei

Sequence statusi: Complete.

P49196-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDAGGDVQV APAAVAQGPM DKEGALRAVL RAAHHADGLA KGLHETCKAL
60 70 80 90 100
DKREAHFCVL AENCDEPQYV KLVETLCAEH QIPLIKVADK KIIGEYCGLC
110 120 130 140
KYDKEGKARK VVGCSSAVVT NWGNEEQGRA ILTDYFASKN
Length:140
Mass (Da):15,069
Last modified:August 29, 2001 - v2
Checksum:i3B6E932D087B77AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080172 Genomic DNA Translation: CCD61763.1
RefSeqiNP_498221.1, NM_065820.5
UniGeneiCel.18085

Genome annotation databases

EnsemblMetazoaiF54E7.2.1; F54E7.2.1; WBGene00004481
F54E7.2.2; F54E7.2.2; WBGene00004481
F54E7.2.3; F54E7.2.3; WBGene00004481
F54E7.2.4; F54E7.2.4; WBGene00004481
GeneIDi175786
KEGGicel:CELE_F54E7.2
UCSCiF54E7.2.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiRS12_CAEEL
AccessioniPrimary (citable) accession number: P49196
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: August 29, 2001
Last modified: February 28, 2018
This is version 114 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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