UniProtKB - P49146 (NPY2R_HUMAN)

BLAST

>sp|P49146|NPY2R_HUMAN Neuropeptide Y receptor type 2 OS=Homo sapiens OX=9606 GN=NPY2R PE=1 SV=1
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGP
VLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA
SPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYT
RIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL
KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAK
KNLEVRKNSGPNDSFTEATNV

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History
Entry version 160 (07 Nov 2018)
Sequence version 1 (01 Feb 1996)
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Protein

Neuropeptide Y receptor type 2

Gene

NPY2R

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.

GO - Molecular functionⁱ

calcium channel regulator activity
Source: ProtInc
Traceable author statementⁱ
- 8132547
neuropeptide Y receptor activity
Source: ProtInc
Traceable author statementⁱ
- 7559383
peptide YY receptor activity Source: Ensembl
signaling receptor activity
Source: ProtInc
Traceable author statementⁱ
- 1321422

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Source: ProtInc
Traceable author statementⁱ
- 7559383
aging Source: Ensembl
behavioral fear response Source: Ensembl
cardiac left ventricle morphogenesis
Source: BHF-UCL
Inferred from mutant phenotypeⁱ
- 19593212
G protein-coupled receptor signaling pathway Source: Reactome
locomotory behavior
Source: ProtInc
Traceable author statementⁱ
- 9692752
negative regulation of cAMP-mediated signaling Source: Ensembl
negative regulation of excitatory postsynaptic potential Source: Ensembl
negative regulation of feeding behavior Source: Ensembl
negative regulation of secretion Source: Ensembl
negative regulation of synaptic transmission, glutamatergic Source: Ensembl
nitric oxide mediated signal transduction Source: Ensembl
outflow tract morphogenesis
Source: BHF-UCL
Inferred from mutant phenotypeⁱ
- 19593212
positive regulation of cell-substrate adhesion Source: Ensembl
positive regulation of circadian sleep/wake cycle, non-REM sleep Source: Ensembl
positive regulation of cytosolic calcium ion concentration Source: Ensembl
positive regulation of dopamine secretion Source: Ensembl
positive regulation of peptide secretion Source: Ensembl
positive regulation of smooth muscle contraction Source: Ensembl
regulation of sensory perception of pain Source: Ensembl
secretion Source: Ensembl

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	G-protein coupled receptor, Receptor, Transducer

Molecular function

G-protein coupled receptor, Receptor, Transducer

Enzyme and pathway databases

Reactomeⁱ	R-HSA-375276 Peptide ligand-binding receptors R-HSA-418594 G alpha (i) signalling events
SIGNORⁱ	P49146

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Neuropeptide Y receptor type 2 Short name: NPY2-R Alternative name(s): NPY-Y2 receptor Short name: Y2 receptor
Gene namesⁱ	Name:NPY2R
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 4

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000185149.5
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:7957 NPY2R
MIMⁱ	162642 gene
neXtProtⁱ	NX_P49146

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 51	ExtracellularSequence analysisAdd BLAST	51
Transmembraneⁱ	52 – 72	Helical; Name=1Sequence analysisAdd BLAST	21
Topological domainⁱ	73 – 86	CytoplasmicSequence analysisAdd BLAST	14
Transmembraneⁱ	87 – 107	Helical; Name=2Sequence analysisAdd BLAST	21
Topological domainⁱ	108 – 124	ExtracellularSequence analysisAdd BLAST	17
Transmembraneⁱ	125 – 145	Helical; Name=3Sequence analysisAdd BLAST	21
Topological domainⁱ	146 – 165	CytoplasmicSequence analysisAdd BLAST	20
Transmembraneⁱ	166 – 186	Helical; Name=4Sequence analysisAdd BLAST	21
Topological domainⁱ	187 – 216	ExtracellularSequence analysisAdd BLAST	30
Transmembraneⁱ	217 – 237	Helical; Name=5Sequence analysisAdd BLAST	21
Topological domainⁱ	238 – 268	CytoplasmicSequence analysisAdd BLAST	31
Transmembraneⁱ	269 – 289	Helical; Name=6Sequence analysisAdd BLAST	21
Topological domainⁱ	290 – 304	ExtracellularSequence analysisAdd BLAST	15
Transmembraneⁱ	305 – 325	Helical; Name=7Sequence analysisAdd BLAST	21
Topological domainⁱ	326 – 381	CytoplasmicSequence analysisAdd BLAST	56

Keywords - Cellular componentⁱ

Cell membrane, Membrane

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	4887
Open Targets More...OpenTargetsⁱ	ENSG00000185149
PharmGKBⁱ	PA31741

Chemistry databases

ChEMBLⁱ	CHEMBL4018
Drug and drug target database More...DrugBankⁱ	DB05004 AC162352 DB00847 Cysteamine DB05045 TM30338
IUPHAR/BPS Guide to PHARMACOLOGY More...GuidetoPHARMACOLOGYⁱ	306

Polymorphism and mutation databases

BioMutaⁱ	NPY2R
DMDMⁱ	1352610

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000069928	1 – 381	Neuropeptide Y receptor type 2Add BLAST		381

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Glycosylationⁱ	11	N-linked (GlcNAc...) asparagineSequence analysis	1
Disulfide bondⁱ	123 ↔ 203	PROSITE-ProRule annotation
Lipidationⁱ	342	S-palmitoyl cysteineSequence analysis	1

Keywords - PTMⁱ

Disulfide bond, Glycoprotein, Lipoprotein, Palmitate

Proteomic databases

EPDⁱ	P49146
PaxDbⁱ	P49146
PeptideAtlas More...PeptideAtlasⁱ	P49146
PRIDEⁱ	P49146
ProteomicsDBⁱ	55966

PTM databases

iPTMnetⁱ	P49146
PhosphoSitePlusⁱ	P49146

Expressionⁱ

Tissue specificityⁱ

High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.

Gene expression databases

Bgeeⁱ	ENSG00000185149 Expressed in 83 organ(s), highest expression level in Ammon's horn
CleanExⁱ	HS_NPY2R
Genevisibleⁱ	P49146 HS

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
PYY	P10082	2	EBI-6655721,EBI-6655667

With

Entry

#Exp.

IntAct

Notes

PYY

P10082

EBI-6655721,EBI-6655667

Protein-protein interaction databases

BioGridⁱ	110947, 62 interactors
IntActⁱ	P49146, 3 interactors
STRINGⁱ	9606.ENSP00000332591

Chemistry databases

BindingDBⁱ

P49146

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P49146
SMRⁱ	P49146
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG3656 Eukaryota ENOG410XRW9 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00930000150833
HOGENOMⁱ	HOG000050229
HOVERGENⁱ	HBG105675
InParanoidⁱ	P49146
KEGG Orthology (KO) More...KOⁱ	K04205
OMAⁱ	AFQCEQR
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0C6Q
PhylomeDBⁱ	P49146
TreeFamⁱ	TF315303

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR001358 NPY2_rcpt IPR000611 NPY_rcpt
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN PR01014 NRPEPTIDEY2R PR01012 NRPEPTIDEYR
SMARTⁱ	View protein in SMART SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

P49146-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MGPIGAEADE NQTVEEMKVE QYGPQTTPRG ELVPDPEPEL IDSTKLIEVQ 
        60         70         80         90        100
VVLILAYCSI ILLGVIGNSL VIHVVIKFKS MRTVTNFFIA NLAVADLLVN 
       110        120        130        140        150
TLCLPFTLTY TLMGEWKMGP VLCHLVPYAQ GLAVQVSTIT LTVIALDRHR 
       160        170        180        190        200
CIVYHLESKI SKRISFLIIG LAWGISALLA SPLAIFREYS LIEIIPDFEI 
       210        220        230        240        250
VACTEKWPGE EKSIYGTVYS LSSLLILYVL PLGIISFSYT RIWSKLKNHV 
       260        270        280        290        300
SPGAANDHYH QRRQKTTKML VCVVVVFAVS WLPLHAFQLA VDIDSQVLDL 
       310        320        330        340        350
KEYKLIFTVF HIIAMCSTFA NPLLYGWMNS NYRKAFLSAF RCEQRLDAIH 
       360        370        380 
SEVSVTFKAK KNLEVRKNSG PNDSFTEATN V

Length:381

Mass (Da):42,731

Last modified:February 1, 1996 - v1

Checksum:ⁱ7D018C0169597BC7

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	134	V → A in AAA93170 (PubMed:7559383).Curated	1
Sequence conflictⁱ	172	A → G (PubMed:8643460).Curated	1
Sequence conflictⁱ	174	G → R (PubMed:8643460).Curated	1
Sequence conflictⁱ	202	A → P in AAB07760 (PubMed:8643460).Curated	1
Sequence conflictⁱ	209	G → A in AAB07760 (PubMed:8643460).Curated	1
Sequence conflictⁱ	248	N → S in AAD00248 (Ref. 6) Curated	1
Sequence conflictⁱ	311	H → Y in AAD00248 (Ref. 6) Curated	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U36269 mRNA Translation: AAC50281.1 U42766 mRNA Translation: AAB04120.1 U32500 mRNA Translation: AAA93170.1 U42389 mRNA Translation: AAB07760.1 U50146 Genomic DNA Translation: AAC51115.1 U76254 Genomic DNA Translation: AAD00248.1 AY236540 Genomic DNA Translation: AAO92062.1 AC104407 Genomic DNA Translation: AAY40940.1 CH471056 Genomic DNA Translation: EAX04901.1 BC075053 mRNA Translation: AAH75053.2 BC075052 mRNA Translation: AAH75052.2
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS3791.1
PIRⁱ	I39187
NCBI Reference Sequences More...RefSeqⁱ	NP_000901.1, NM_000910.3 XP_005263090.1, XM_005263033.4 XP_005263091.1, XM_005263034.4
UniGeneⁱ	Hs.37125

Genome annotation databases

Ensemblⁱ	ENST00000329476; ENSP00000332591; ENSG00000185149 ENST00000506608; ENSP00000426366; ENSG00000185149
GeneIDⁱ	4887
KEGGⁱ	hsa:4887
UCSC genome browser More...UCSCⁱ	uc003ioq.3 human

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P49146	Neuropeptide Y receptor type 2		PANTR		381	UniRef100_P49146
Uncharacterized protein		PANPA		383
NPY2R isoform 1		PONAB		381
Neuropeptide Y receptor type 2		PANTR		383
NPY2R isoform 1		PANTR		381

Protein	Similar proteins		Species	Score	Length	Source
P49146	Neuropeptide Y receptor type 2		PANTR		381	UniRef90_P49146
Neuropeptide Y receptor type 2		CAVPO		381
Neuropeptide Y receptor type 2		MACMU		381
Uncharacterized protein		PANPA		383
NPY2R isoform 1		PONAB		381
+29

Protein	Similar proteins		Species	Score	Length	Source
P49146	Neuropeptide Y receptor type 2		PANTR		381	UniRef50_P49146
Neuropeptide Y receptor type 2		MACMU		381
Neuropeptide Y receptor type 2		CAVPO		381
Neuropeptide Y receptor type 2		BOVIN		384
Neuropeptide Y receptor type 2		PIG		382
+307

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U36269 mRNA Translation: AAC50281.1 U42766 mRNA Translation: AAB04120.1 U32500 mRNA Translation: AAA93170.1 U42389 mRNA Translation: AAB07760.1 U50146 Genomic DNA Translation: AAC51115.1 U76254 Genomic DNA Translation: AAD00248.1 AY236540 Genomic DNA Translation: AAO92062.1 AC104407 Genomic DNA Translation: AAY40940.1 CH471056 Genomic DNA Translation: EAX04901.1 BC075053 mRNA Translation: AAH75053.2 BC075052 mRNA Translation: AAH75052.2
CCDSⁱ	CCDS3791.1
PIRⁱ	I39187
RefSeqⁱ	NP_000901.1, NM_000910.3 XP_005263090.1, XM_005263033.4 XP_005263091.1, XM_005263034.4
UniGeneⁱ	Hs.37125

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	2IK3	model	-	@	1-381	[»]
ProteinModelPortalⁱ	P49146
SMRⁱ	P49146
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	110947, 62 interactors
IntActⁱ	P49146, 3 interactors
STRINGⁱ	9606.ENSP00000332591

Chemistry databases

BindingDBⁱ	P49146
ChEMBLⁱ	CHEMBL4018
DrugBankⁱ	DB05004 AC162352 DB00847 Cysteamine DB05045 TM30338
GuidetoPHARMACOLOGYⁱ	306

Protein family/group databases

GPCRDBⁱ	Search...

GPCRDBⁱ

Search...

PTM databases

iPTMnetⁱ	P49146
PhosphoSitePlusⁱ	P49146

Polymorphism and mutation databases

BioMutaⁱ	NPY2R
DMDMⁱ	1352610

Proteomic databases

EPDⁱ	P49146
PaxDbⁱ	P49146
PeptideAtlasⁱ	P49146
PRIDEⁱ	P49146
ProteomicsDBⁱ	55966

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000329476; ENSP00000332591; ENSG00000185149 ENST00000506608; ENSP00000426366; ENSG00000185149
GeneIDⁱ	4887
KEGGⁱ	hsa:4887
UCSCⁱ	uc003ioq.3 human

Organism-specific databases

CTDⁱ	4887
DisGeNETⁱ	4887
EuPathDBⁱ	HostDB:ENSG00000185149.5
GeneCardsⁱ	NPY2R
HGNCⁱ	HGNC:7957 NPY2R
MIMⁱ	162642 gene
neXtProtⁱ	NX_P49146
OpenTargetsⁱ	ENSG00000185149
PharmGKBⁱ	PA31741
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG3656 Eukaryota ENOG410XRW9 LUCA
GeneTreeⁱ	ENSGT00930000150833
HOGENOMⁱ	HOG000050229
HOVERGENⁱ	HBG105675
InParanoidⁱ	P49146
KOⁱ	K04205
OMAⁱ	AFQCEQR
OrthoDBⁱ	EOG091G0C6Q
PhylomeDBⁱ	P49146
TreeFamⁱ	TF315303

Enzyme and pathway databases

Reactomeⁱ	R-HSA-375276 Peptide ligand-binding receptors R-HSA-418594 G alpha (i) signalling events
SIGNORⁱ	P49146

Miscellaneous databases

GeneWikiⁱ	Neuropeptide_Y_receptor_Y2
GenomeRNAiⁱ	4887
Protein Ontology More...PROⁱ	PR:P49146
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000185149 Expressed in 83 organ(s), highest expression level in Ammon's horn
CleanExⁱ	HS_NPY2R
Genevisibleⁱ	P49146 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR001358 NPY2_rcpt IPR000611 NPY_rcpt
Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN PR01014 NRPEPTIDEY2R PR01012 NRPEPTIDEYR
SMARTⁱ	View protein in SMART SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	NPY2R_HUMAN
Accessionⁱ	P49146Primary (citable) accession number: P49146 Secondary accession number(s): Q13281 , Q13457, Q4W5G7, Q6AZZ6, Q9UE67
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	February 1, 1996
	Last sequence update:	February 1, 1996
	Last modified:	November 7, 2018
	This is version 160 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human chromosome 4
Human chromosome 4: entries, gene names and cross-references to MIM
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
PDB cross-references
Index of Protein Data Bank (PDB) cross-references
7-transmembrane G-linked receptors
List of 7-transmembrane G-linked receptor entries

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UniProtKB - P49146 (NPY2R_HUMAN)

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Neuropeptide Y receptor type 2

NPY2R

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma membrane

Plasma Membrane

Other locations

Topology

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Chemistry databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

Protein family/group databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ