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Protein

Transaldolase 2

Gene

tal2

Organism
Nostoc punctiforme (strain ATCC 29133 / PCC 73102)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Transaldolase (Npun_F5864), Transaldolase 2 (tal2), Transaldolase (tal)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei141Schiff-base intermediate with substrateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processPentose shunt
LigandSchiff base

Enzyme and pathway databases

BioCyciNPUN63737:G1GBR-4105-MONOMER
UniPathwayiUPA00115; UER00414

Names & Taxonomyi

Protein namesi
Recommended name:
Transaldolase 2 (EC:2.2.1.2)
Gene namesi
Name:tal2
Ordered Locus Names:Npun_F4024
OrganismiNostoc punctiforme (strain ATCC 29133 / PCC 73102)
Taxonomic identifieri63737 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
Proteomesi
  • UP000001191 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001736291 – 381Transaldolase 2Add BLAST381

Interactioni

Protein-protein interaction databases

STRINGi63737.Npun_F4024

Structurei

3D structure databases

ProteinModelPortaliP48983
SMRiP48983
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 2 subfamily.Curated

Phylogenomic databases

eggNOGiENOG4107QQX Bacteria
COG0176 LUCA
HOGENOMiHOG000226074
KOiK00616
OMAiATECYYQ
OrthoDBiPOG091H05PS
PhylomeDBiP48983

Family and domain databases

CDDicd00955 Transaldolase_like, 1 hit
Gene3Di3.20.20.70, 1 hit
HAMAPiMF_00493 Transaldolase_2, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR001585 TAL/FSA
IPR004732 Transaldolase_2
IPR018225 Transaldolase_AS
PANTHERiPTHR10683 PTHR10683, 1 hit
PTHR10683:SF19 PTHR10683:SF19, 1 hit
PfamiView protein in Pfam
PF00923 TAL_FSA, 1 hit
PIRSFiPIRSF036915 Trnald_Bac_Plnt, 1 hit
TIGRFAMsiTIGR00876 tal_mycobact, 1 hit
PROSITEiView protein in PROSITE
PS01054 TRANSALDOLASE_1, 1 hit
PS00958 TRANSALDOLASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

P48983-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTNHLLEIK QYGQSIWMDN LTRDIIQSGE LKDMVENQGI SGITSNPAIF
60 70 80 90 100
EKAIAGNAIY DADIEAGVRA GLPIYKIYES LVFADIRNAC DILRPVYEAS
110 120 130 140 150
NRLDGYVSIE VPPTIAHDTE ATISEARRYF QEIGRENLMI KIPGTEPGLP
160 170 180 190 200
AVEQVIAEGM NVNITLLFSV ESYVNTAWAY VRGLEKRLAE GKDISRIASV
210 220 230 240 250
ASFFLSRIDS NIDAKIDAKL KKGVDDIAVE AKLKAVKGKV AIANAKLAYQ
260 270 280 290 300
EYKKIIRSER WQELVAKGAT VQRLLWASTS TKDPNYNDVM YIEELVGPDT
310 320 330 340 350
VNTVPPATIK ACADHCNVSD RLETDVNNAY TLIENLKDPD INIDLDTVMD
360 370 380
ELLVEGIDKF IQPFQSLMNS LEDKIKVLSP V
Length:381
Mass (Da):42,303
Last modified:February 1, 1996 - v1
Checksum:i906E28CDE77755F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L32796 Genomic DNA Translation: AAA50769.1
CP001037 Genomic DNA Translation: ACC82403.1
RefSeqiWP_012410370.1, NC_010628.1

Genome annotation databases

EnsemblBacteriaiACC82403; ACC82403; Npun_F4024
KEGGinpu:Npun_F4024

Similar proteinsi

Entry informationi

Entry nameiTAL2_NOSP7
AccessioniPrimary (citable) accession number: P48983
Secondary accession number(s): B2J6J8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: February 28, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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