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Entry version 167 (16 Oct 2019)
Sequence version 2 (23 Jan 2007)
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Protein

Phosphatidylinositol transfer protein beta isoform

Gene

PITPNB

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTransport
LigandLipid-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-1483196 PI and PC transport between ER and Golgi membranes

Chemistry databases

SwissLipids knowledge resource for lipid biology

More...
SwissLipidsi
SLP:000000416

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Phosphatidylinositol transfer protein beta isoform
Short name:
PI-TP-beta
Short name:
PtdIns transfer protein beta
Short name:
PtdInsTP beta
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PITPNB
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:9002 PITPNB

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
606876 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P48739

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Golgi apparatus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
23760

Open Targets

More...
OpenTargetsi
ENSG00000180957

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA33336

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P48739

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PITPNB

Domain mapping of disease mutations (DMDM)

More...
DMDMi
1346772

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001916431 – 271Phosphatidylinositol transfer protein beta isoformAdd BLAST271

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei215N6-acetyllysineCombined sources1
Modified residuei262PhosphoserineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Constitutive phosphorylation of Ser-262 has no effect on phospholipid transfer activity but is required for Golgi targeting.By similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P48739

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P48739

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P48739

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P48739

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P48739

PeptideAtlas

More...
PeptideAtlasi
P48739

PRoteomics IDEntifications database

More...
PRIDEi
P48739

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
55934 [P48739-1]
55935 [P48739-2]
6893

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P48739

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P48739

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P48739

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed in various tissues including brain.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000180957 Expressed in 241 organ(s), highest expression level in gingival epithelium

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P48739 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P48739 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA000528

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
117261, 26 interactors

Protein interaction database and analysis system

More...
IntActi
P48739, 5 interactors

Molecular INTeraction database

More...
MINTi
P48739

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000321266

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P48739

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3668 Eukaryota
COG5083 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155101

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000006717

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P48739

Identification of Orthologs from Complete Genome Data

More...
OMAi
LSYTIMK

Database of Orthologous Groups

More...
OrthoDBi
951268at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P48739

TreeFam database of animal gene trees

More...
TreeFami
TF313279

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.530.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001666 PI_transfer
IPR023393 START-like_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10658 PTHR10658, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02121 IP_trans, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00391 PITRANSFER

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P48739-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MVLIKEFRVV LPCSVQEYQV GQLYSVAEAS KNETGGGEGI EVLKNEPYEK
60 70 80 90 100
DGEKGQYTHK IYHLKSKVPA FVRMIAPEGS LVFHEKAWNA YPYCRTIVTN
110 120 130 140 150
EYMKDDFFIK IETWHKPDLG TLENVHGLDP NTWKTVEIVH IDIADRSQVE
160 170 180 190 200
PADYKADEDP ALFQSVKTKR GPLGPNWKKE LANSPDCPQM CAYKLVTIKF
210 220 230 240 250
KWWGLQSKVE NFIQKQEKRI FTNFHRQLFC WIDKWIDLTM EDIRRMEDET
260 270
QKELETMRKR GSVRGTSAAD V
Length:271
Mass (Da):31,540
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAC5333FBC0F6CA06
GO
Isoform 2 (identifier: P48739-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     257-271: MRKRGSVRGTSAADV → LRNQGQVRGTSAASDE

Show »
Length:272
Mass (Da):31,638
Checksum:i05142EA9F80BA7CB
GO
Isoform 3 (identifier: P48739-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-7: MVLIKEF → MGDLLMEKC

Show »
Length:273
Mass (Da):31,700
Checksum:i547F67C88E573741
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0A0MSW4A0A0A0MSW4_HUMAN
Phosphatidylinositol transfer prote...
PITPNB
271Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B3KYB6B3KYB6_HUMAN
Phosphatidylinositol transfer prote...
PITPNB
120Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B3KYB7B3KYB7_HUMAN
Phosphatidylinositol transfer prote...
PITPNB
167Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0551321 – 7MVLIKEF → MGDLLMEKC in isoform 3. 1 Publication7
Alternative sequenceiVSP_012762257 – 271MRKRG…SAADV → LRNQGQVRGTSAASDE in isoform 2. 1 PublicationAdd BLAST15

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
D30037 mRNA Translation: BAA06277.1
CR456541 mRNA Translation: CAG30427.1
AK302367 mRNA Translation: BAH13686.1
AL031591 Genomic DNA No translation available.
CH471095 Genomic DNA Translation: EAW59743.1
BC018704 mRNA Translation: AAH18704.1
BC031427 mRNA Translation: AAH31427.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13842.1 [P48739-1]
CCDS63432.1 [P48739-3]
CCDS63433.1 [P48739-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001271206.1, NM_001284277.1 [P48739-2]
NP_001271207.1, NM_001284278.1 [P48739-3]
NP_036531.1, NM_012399.4 [P48739-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000320996; ENSP00000321266; ENSG00000180957 [P48739-2]
ENST00000335272; ENSP00000334738; ENSG00000180957 [P48739-1]
ENST00000634017; ENSP00000487693; ENSG00000180957 [P48739-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
23760

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:23760

UCSC genome browser

More...
UCSCi
uc003adk.5 human [P48739-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D30037 mRNA Translation: BAA06277.1
CR456541 mRNA Translation: CAG30427.1
AK302367 mRNA Translation: BAH13686.1
AL031591 Genomic DNA No translation available.
CH471095 Genomic DNA Translation: EAW59743.1
BC018704 mRNA Translation: AAH18704.1
BC031427 mRNA Translation: AAH31427.1
CCDSiCCDS13842.1 [P48739-1]
CCDS63432.1 [P48739-3]
CCDS63433.1 [P48739-2]
RefSeqiNP_001271206.1, NM_001284277.1 [P48739-2]
NP_001271207.1, NM_001284278.1 [P48739-3]
NP_036531.1, NM_012399.4 [P48739-1]

3D structure databases

SMRiP48739
ModBaseiSearch...

Protein-protein interaction databases

BioGridi117261, 26 interactors
IntActiP48739, 5 interactors
MINTiP48739
STRINGi9606.ENSP00000321266

Chemistry databases

SwissLipidsiSLP:000000416

PTM databases

iPTMnetiP48739
PhosphoSitePlusiP48739
SwissPalmiP48739

Polymorphism and mutation databases

BioMutaiPITPNB
DMDMi1346772

Proteomic databases

EPDiP48739
jPOSTiP48739
MassIVEiP48739
MaxQBiP48739
PaxDbiP48739
PeptideAtlasiP48739
PRIDEiP48739
ProteomicsDBi55934 [P48739-1]
55935 [P48739-2]
6893

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
23760

Genome annotation databases

EnsembliENST00000320996; ENSP00000321266; ENSG00000180957 [P48739-2]
ENST00000335272; ENSP00000334738; ENSG00000180957 [P48739-1]
ENST00000634017; ENSP00000487693; ENSG00000180957 [P48739-3]
GeneIDi23760
KEGGihsa:23760
UCSCiuc003adk.5 human [P48739-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23760
DisGeNETi23760

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PITPNB
HGNCiHGNC:9002 PITPNB
HPAiHPA000528
MIMi606876 gene
neXtProtiNX_P48739
OpenTargetsiENSG00000180957
PharmGKBiPA33336

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3668 Eukaryota
COG5083 LUCA
GeneTreeiENSGT00940000155101
HOGENOMiHOG000006717
InParanoidiP48739
OMAiLSYTIMK
OrthoDBi951268at2759
PhylomeDBiP48739
TreeFamiTF313279

Enzyme and pathway databases

ReactomeiR-HSA-1483196 PI and PC transport between ER and Golgi membranes

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PITPNB human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
PITPNB

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
23760
PharosiP48739

Protein Ontology

More...
PROi
PR:P48739

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000180957 Expressed in 241 organ(s), highest expression level in gingival epithelium
ExpressionAtlasiP48739 baseline and differential
GenevisibleiP48739 HS

Family and domain databases

Gene3Di3.30.530.20, 1 hit
InterProiView protein in InterPro
IPR001666 PI_transfer
IPR023393 START-like_dom_sf
PANTHERiPTHR10658 PTHR10658, 1 hit
PfamiView protein in Pfam
PF02121 IP_trans, 1 hit
PRINTSiPR00391 PITRANSFER

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPIPNB_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P48739
Secondary accession number(s): B3KYB8, B7Z7Q0, Q8N5W1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: January 23, 2007
Last modified: October 16, 2019
This is version 167 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
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