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Protein

40S ribosomal protein S25

Gene

RpS25

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cytoplasmic translation Source: FlyBase

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DME-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-DME-1799339 SRP-dependent cotranslational protein targeting to membrane
R-DME-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-DME-72649 Translation initiation complex formation
R-DME-72689 Formation of a pool of free 40S subunits
R-DME-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-DME-72702 Ribosomal scanning and start codon recognition
R-DME-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-DME-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-DME-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S25
Gene namesi
Name:RpS25
Synonyms:RpS31
ORF Names:CG6684
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0086472 RpS25

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001928771 – 11740S ribosomal protein S25Add BLAST117

Proteomic databases

PaxDbiP48588
PRIDEiP48588

Expressioni

Gene expression databases

BgeeiFBgn0086472
ExpressionAtlasiP48588 baseline and differential
GenevisibleiP48588 DM

Interactioni

Protein-protein interaction databases

BioGridi66477, 17 interactors
DIPiDIP-17632N
IntActiP48588, 25 interactors
STRINGi7227.FBpp0081845

Structurei

3D structure databases

ProteinModelPortaliP48588
SMRiP48588
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1767 Eukaryota
COG4901 LUCA
GeneTreeiENSGT00390000004856
InParanoidiP48588
KOiK02975
OMAiKEVPTFR
OrthoDBiEOG091G134K
PhylomeDBiP48588

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR004977 Ribosomal_S25
IPR036388 WH-like_DNA-bd_sf
PANTHERiPTHR12850 PTHR12850, 1 hit
PfamiView protein in Pfam
PF03297 Ribosomal_S25, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD012268 Ribosomal_S25, 1 hit

Sequencei

Sequence statusi: Complete.

P48588-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPKKDAKSS AKQPQKTQKK KEGSGGGKAK KKKWSKGKVR DKLNNQVLFD
60 70 80 90 100
KATYEKLYKE VPAYKLITPS VVSERLKIRG SLAKRALIEL REKGLIKQVV
110
QHHSQVIYTR ATKGDEA
Length:117
Mass (Da):13,201
Last modified:August 15, 2003 - v3
Checksum:i1EBE36B8FD8896D6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti83A → D in AAA03464 (Ref. 5) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014297 Genomic DNA Translation: AAN13495.1
AY071076 mRNA Translation: AAL48698.1
BT050549 mRNA Translation: ACJ13256.1
U03289 Unassigned DNA Translation: AAA03464.1
RefSeqiNP_524315.2, NM_079591.6
NP_731544.1, NM_169376.3
UniGeneiDm.1146

Genome annotation databases

EnsemblMetazoaiFBtr0082369; FBpp0081845; FBgn0086472
FBtr0082370; FBpp0081846; FBgn0086472
GeneIDi41343
KEGGidme:Dmel_CG6684

Similar proteinsi

Entry informationi

Entry nameiRS25_DROME
AccessioniPrimary (citable) accession number: P48588
Secondary accession number(s): B6IDV9
, Q0KI84, Q8SZ71, Q9VGS0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: August 15, 2003
Last modified: July 18, 2018
This is version 128 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

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