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  1. 1
    "Cloning and sequencing of the cDNA for the light subunit of human liver gamma-glutamylcysteine synthetase and relative mRNA levels for heavy and light subunits in human normal tissues."
    Gipp J.J., Bailey H.H., Mulcahy R.T.
    Biochem. Biophys. Res. Commun. 206:584-589(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Category: Sequences.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).
  2. 2
    "Homo sapiens GCLM mRNA for glutamate-cysteine ligase, modifier subunit delta2 alternative splicing variant, complete cds."
    Sawada Y., Sudo M., Fujii A., Mizuochi A., Hisatomi H.
    Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), ALTERNATIVE SPLICING.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  3. 3
    "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  4. 4
    NIEHS SNPs program
    Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANT MET-209.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  5. 5
    "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Category: Sequences.
    Tissue: Brain.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 12931 other entries.

  6. 6
    "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 5638 other entries.

  7. 7
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  8. 8
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Category: Sequences.
    Tissue: Brain.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50471 other entries.

  9. 9
    "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
    Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
    Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-263, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3091 other entries.

  10. 10
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 18099 other entries.

  11. 11
    "Polymorphism in the 5'-flanking region of human glutamate-cysteine ligase modifier subunit gene is associated with myocardial infarction."
    Nakamura S., Kugiyama K., Sugiyama S., Miyamoto S., Koide S., Fukushima H., Honda O., Yoshimura M., Ogawa H.
    Circulation 105:2968-2973(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: Polymorphism in the 5'-flanking region is associated with myocardial infarction; Observational study of gene-disease association. (HuGE Navigator)Imported, Associated with CARDIOVASCULAR: myocardial infarction.Imported.
    Source: GAD:123885, GeneRIF:2730.

    This publication is mapped to 3 other entries.

  12. 12
    "Polymorphism in glutamate-cysteine ligase modifier subunit gene is associated with impairment of nitric oxide-mediated coronary vasomotor function."
    Nakamura S., Sugiyama S., Fujioka D., Kawabata K., Ogawa H., Kugiyama K.
    Circulation 108:1425-1427(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: Observational study of gene-disease association. (HuGE Navigator); A -588T polymorphism of the GCLM gene causes a decrease in endothelial NO bioactivity causing impairment of endothelium-dependent vasomotor function in large and resistance coronary arteries. The GCL-GSH-NO axis may defend against coronary artery diseaseImported, Associated with CARDIOVASCULAR: atherosclerosis, coronary.Imported.
    Source: GeneRIF:2730, GAD:123886.

    This publication is mapped to 13 other entries.

  13. 13
    "The modifier subunit of glutamate cysteine ligase (GCLM) is a molecular target for amelioration of cisplatin resistance in lung cancer."
    Inoue Y., Tomisawa M., Yamazaki H., Abe Y., Suemizu H., Tsukamoto H., Tomii Y., Kawamura M., Kijima H., Hatanaka H., Ueyama Y., Nakamura M., Kobayashi K.
    Int. J. Oncol. 23:1333-1339(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: GCLM has a role in cisplatin (CDDP)-resistance in lung cancerImported.
    Source: GeneRIF:2730.

    This publication is mapped to 3 other entries.

  14. 14
    "Human glutamate cysteine ligase gene regulation through the electrophile response element."
    Dickinson D.A., Levonen A.L., Moellering D.R., Arnold E.K., Zhang H., Darley-Usmar V.M., Forman H.J.
    Free Radic. Biol. Med. 37:1152-1159(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: Review. The most important element in both Gclc and Gclm expression is the electrophile response element in their promoters.Imported.
    Source: GeneRIF:2730.

    This publication is mapped to 8 other entries.

  15. 15
    "Delayed mechanism for induction of gamma-glutamylcysteine synthetase heavy subunit mRNA stability by oxidative stress involving p38 mitogen-activated protein kinase signaling."
    Song I.S., Tatebe S., Dai W., Kuo M.T.
    J. Biol. Chem. 280:28230-28240(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Sequences.
    Annotation: Reduction-oxidation regulation of gamma-GCSh expression is mediated by p38 mitogen-activated protein kinase signaling.Imported.
    Source: GeneRIF:2730.

    This publication is mapped to 9 other entries.

  16. 16
    "Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels."
    Chen Y., Shertzer H.G., Schneider S.N., Nebert D.W., Dalton T.P.
    J. Biol. Chem. 280:33766-33774(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: in most tissues glutanmate-cysteine ligase modifier submit (GCLM) is limiting suggesting an increase in GCLM alone would increase gamma-GC synthesis; in kidney gamma-GC synthesis may be controlled post-translationallyImported.
    Source: GeneRIF:2730.

    This publication is mapped to 12 other entries.

  17. 17
    "Polymorphisms in glutathione-related genes affect methylmercury retention."
    Custodio H.M., Broberg K., Wennberg M., Jansson J.H., Vessby B., Hallmans G., Stegmayr B., Skerfving S.
    Arch. Environ. Health 59:588-595(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator)Imported.
    Source: GeneRIF:2730.

    This publication is mapped to 37 other entries.

  18. 18
    "[The relationship between the polymorphism of glutamate cysteine ligase modulatory subunit gene and the susceptibility to chronic obstructive pulmonary disease]."
    Hu R.C., Tan S.X., Dai A.G.
    Zhonghua Jie He He Hu Xi Za Zhi 29:100-103(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: Associated with IMMUNE: chronic obstructive pulmonary disease/COPD.Imported, Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator); The polymorphism of GCLM -588C/T and -23G/T sites were associated with susceptibility to COPD.Imported.
    Source: GAD:147952, GeneRIF:2730.

    This publication is mapped to 3 other entries.

  19. 19
    "Chronic beryllium disease and glutathione biosynthesis genes."
    Bekris L.M., Viernes H.M., Farin F.M., Maier L.A., Kavanagh T.J., Takaro T.K.
    J. Occup. Environ. Med. 48:599-606(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator)Imported.
    Source: GeneRIF:2730.

    This publication is mapped to 8 other entries.

  20. 20
    "Schizophrenia and oxidative stress: glutamate cysteine ligase modifier as a susceptibility gene."
    Tosic M., Ott J., Barral S., Bovet P., Deppen P., Gheorghita F., Matthey M.L., Parnas J., Preisig M., Saraga M., Solida A., Timm S., Wang A.G., Werge T., Cuenod M., Do K.Q.
    Am. J. Hum. Genet. 79:586-592(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Expression, Sequences.
    Annotation: The gene of the key GSH-synthesizing enzyme glutamate cysteine ligase modifier (GCLM) subunit is strongly associated with schizophrenia in two case-control studies and in one family study.Imported.
    Source: GeneRIF:2730.

    This publication is mapped to 3 other entries.

  21. 21
    "Levels of 2-thiothiazolidine-4-carboxylic acid (TTCA) and effect modification of polymorphisms of glutathione-related genes in vulcanization workers in the southern Sweden rubber industries."
    Jonsson L.S., Broberg K., Bergendorf U., Axmon A., Littorin M., Jonsson B.A.
    Int Arch Occup Environ Health 80:589-598(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)Imported.
    Source: GeneRIF:2730.

    This publication is mapped to 37 other entries.

  22. 22
    "Upregulation of gamma-glutamate-cysteine ligase as part of the long-term adaptation process to iron accumulation in neuronal SH-SY5Y cells."
    Aguirre P., Valdes P., Aracena-Parks P., Tapia V., Nunez M.T.
    Am. J. Physiol., Cell Physiol. 292:C2197-203(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: upregulation of gamma-glutamate-cysteine ligase as part of the long-term adaptation process to iron accumulation in neuronsImported.
    Source: GeneRIF:2730.

    This publication is mapped to 8 other entries.

  23. 23
    Category: Interaction.
    Source: IntAct:P48507.

    This publication is mapped to 1880 other entries.

  24. 24
    "Polymorphisms and vascular cognitive impairment after ischemic stroke."
    Baum L., Chen X., Cheung W.S., Cheung C.K., Cheung L.W., Chiu K.F., Wen H.M., Poon P., Woo K.S., Ng H.K., Wong K.S.
    J Geriatr Psychiatry Neurol 20:93-99(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator)Imported.
    Source: GeneRIF:2730.

    This publication is mapped to 3 other entries.

  25. 25
    "The relationship between polymorphisms in the glutamate cysteine ligase gene and asthma susceptibility."
    Polonikov A.V., Ivanov V.P., Solodilova M.A., Khoroshaya I.V., Kozhuhov M.A., Panfilov V.I.
    Respir Med 101:2422-2424(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator)Imported.
    Source: GeneRIF:2730.

    This publication is mapped to 8 other entries.

1 to 25 of 67  Show
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