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Protein

Serine/threonine-protein phosphatase PP1 isozyme 2

Gene
N/A
Organism
Acetabularia peniculus (Green alga) (Polyphysa peniculus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mn2+By similarityNote: Binds 2 manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi61Manganese 1By similarity1
Metal bindingi63Manganese 1By similarity1
Metal bindingi89Manganese 1By similarity1
Metal bindingi89Manganese 2By similarity1
Metal bindingi121Manganese 2By similarity1
Active sitei122Proton donorBy similarity1
Metal bindingi170Manganese 2By similarity1
Metal bindingi245Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandManganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase PP1 isozyme 2 (EC:3.1.3.16)
OrganismiAcetabularia peniculus (Green alga) (Polyphysa peniculus)
Taxonomic identifieri35862 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeChlorophytaUlvophyceaeDasycladalesPolyphysaceaeAcetabularia

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000587961 – 319Serine/threonine-protein phosphatase PP1 isozyme 2Add BLAST319

Proteomic databases

PRIDEiP48481

Structurei

3D structure databases

ProteinModelPortaliP48481
SMRiP48481
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PPP phosphatase family. PP-1 subfamily.Curated

Family and domain databases

Gene3Di3.60.21.10, 1 hit
InterProiView protein in InterPro
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
IPR006186 Ser/Thr-sp_prot-phosphatase
IPR031675 STPPase_N
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PF16891 STPPase_N, 1 hit
PRINTSiPR00114 STPHPHTASE
SMARTiView protein in SMART
SM00156 PP2Ac, 1 hit
PROSITEiView protein in PROSITE
PS00125 SER_THR_PHOSPHATASE, 1 hit

Sequencei

Sequence statusi: Complete.

P48481-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEESAVDDVI ERLLEVRNNR PGKQVNLAEG EIRQLCLTAK DVFMSQPNLL
60 70 80 90 100
ELEAPIKICG DIHGQYTDLL RLFEYGGFPP EANYLFLGDY VDRGKQSLET
110 120 130 140 150
ICLLLAFKVK YPKNFFLLRG NHECASINRI YGFYDVCKRR YNIRLWKTFT
160 170 180 190 200
DCFNCLPACA LVDEKIICMH GGLSPELKSL DAIRHIPRPT DVPDTGLLCD
210 220 230 240 250
LLWSDPDKDV AGWGENDRGV SYTFGPDTVT GFLQKHDLDL ICRAHQVVED
260 270 280 290 300
GYEFFAKRQL VTLFSAPNYC GEFDNAGALM SVDDTLMCSF QILKPSEKKG
310
KLLYGSGALA GPGRGTPRR
Length:319
Mass (Da):35,924
Last modified:February 1, 1996 - v1
Checksum:i2725A2668FB4BA14
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z28632 Genomic DNA Translation: CAA82264.1

Similar proteinsi

Entry informationi

Entry nameiPP12_ACEPE
AccessioniPrimary (citable) accession number: P48481
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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