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UniProtKB - P48301 (TEAD2_MOUSE)

Entry version 158 (23 Feb 2022)
Sequence version 1 (01 Feb 1996)
Previous versions | rss
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Protein

Transcriptional enhancer factor TEF-4

Gene

Tead2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction (By similarity).

Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.

By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi38 – 114TEAPROSITE-ProRule annotationAdd BLAST77

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-2032785, YAP1- and WWTR1 (TAZ)-stimulated gene expression
R-MMU-8951671, RUNX3 regulates YAP1-mediated transcription

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcriptional enhancer factor TEF-4
Alternative name(s):
ETEF-1
Embryonic TEA domain-containing factor
Short name:
ETF
TEA domain family member 2
Short name:
TEAD-2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Tead2
Synonyms:Etdf, Etf, Tef4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:104904, Tead2

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSMUSG00000030796

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002059331 – 445Transcriptional enhancer factor TEF-4Add BLAST445

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P48301

PRoteomics IDEntifications database

More...PRIDEi		P48301

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		259369

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P48301

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P48301

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highest expression in brain. High levels also found in lung, testis and ovarian follicle cells. Lower levels in heart and spleen.

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

In the embryo, levels fall after fertilization until the 2-4 cell stage and then increase rapidly.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000030796, Expressed in hindlimb bud and 127 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P48301, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with YAP1 and WWTR1/TAZ.

By similarity

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		204099, 3 interactors

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		P48301

Protein interaction database and analysis system

More...IntActi		P48301, 1 interactor

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000103431

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P48301, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P48301

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 47DisorderedSequence analysisAdd BLAST47
Regioni172 – 445Transcriptional activationSequence analysisAdd BLAST274
Regioni191 – 217DisorderedSequence analysisAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi195 – 217Pro residuesSequence analysisAdd BLAST23

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3841, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00950000182956

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_012515_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P48301

Identification of Orthologs from Complete Genome Data

More...OMAi		WQTRALG

Database of Orthologous Groups

More...OrthoDBi		823827at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P48301

TreeFam database of animal gene trees

More...TreeFami		TF313443

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		6.10.20.40, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000818, TEA/ATTS_dom
IPR038096, TEA/ATTS_sf
IPR016361, TEF_metazoa
IPR041086, YBD

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01285, TEA, 1 hit
PF17725, YBD, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF002603, TEF, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00065, TEADOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00426, TEA, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00554, TEA_1, 1 hit
PS51088, TEA_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

P48301-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGDPRTGAPL DDGGGWTGSE EGSEEGTGGS EGVGGDGSPD AEGVWSPDIE 
        60         70         80         90        100
QSFQEALAIY PPCGRRKIIL SDEGKMYGRN ELIARYIKLR TGKTRTRKQV 
       110        120        130        140        150
SSHIQVLARR KSREIQSKLK DQVSKDKAFQ TMATMSSAQL ISAPSLQAKL 
       160        170        180        190        200
GPSGPQATEL FQFWSGSSGP PWNVPDVKPF SQAPFSVSLT PPASDLPGYE 
       210        220        230        240        250
PPPALSPLPP PAPSPPAWQA RALGTARLQL IEFSAFVEPP DAVDSFQRHL 
       260        270        280        290        300
FVHISQQCPS PGAPPLESVD VRQIYDKFPE KKGGLRELYD RGPPHAFFLV 
       310        320        330        340        350
KFWADLNWGP SAEEAGSSGG GGGFYGVSSQ YESRELMTLT CSSKVCSFGK 
       360        370        380        390        400
QVVEKVETER AQLEDGRFVY RLLRSPMCEY LVNFLHKLRQ LPERYMMNSV 
       410        420        430        440 
LENFTILQVV TNRDTQELLL CTAYVFEVST SERGAQYHIY RLVRD
Length:445
Mass (Da):49,041
Last modified:February 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i237BC27A8BF9877C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q80UL2Q80UL2_MOUSE
Tead2 protein
Tead2
410Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1B0GT36A0A1B0GT36_MOUSE
Transcriptional enhancer factor TEF...
Tead2
245Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1B0GRZ4A0A1B0GRZ4_MOUSE
Transcriptional enhancer factor TEF...
Tead2
175Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1B0GSN2A0A1B0GSN2_MOUSE
Transcriptional enhancer factor TEF...
Tead2
107Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1B0GS07A0A1B0GS07_MOUSE
Transcriptional enhancer factor TEF...
Tead2
184Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1B0GR00A0A1B0GR00_MOUSE
Transcriptional enhancer factor TEF...
Tead2
129Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1B0GQX1A0A1B0GQX1_MOUSE
Transcriptional enhancer factor TEF...
Tead2
129Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti289Y → F in CAA64216 (PubMed:8702974).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
D50563 mRNA Translation: BAA09126.1
D83596 Genomic DNA Translation: BAA12018.1
X94442 mRNA Translation: CAA64216.1
Y10026 mRNA Translation: CAA71135.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS21236.1

Protein sequence database of the Protein Information Resource

More...PIRi		A57400

NCBI Reference Sequences

More...RefSeqi		NP_001272427.1, NM_001285498.1
NP_035695.1, NM_011565.2
XP_006540840.1, XM_006540777.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000033060; ENSMUSP00000033060; ENSMUSG00000030796
ENSMUST00000107801; ENSMUSP00000103431; ENSMUSG00000030796

Database of genes from NCBI RefSeq genomes

More...GeneIDi		21677

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:21677

UCSC genome browser

More...UCSCi		uc009gud.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D50563 mRNA Translation: BAA09126.1
D83596 Genomic DNA Translation: BAA12018.1
X94442 mRNA Translation: CAA64216.1
Y10026 mRNA Translation: CAA71135.1
CCDSiCCDS21236.1
PIRiA57400
RefSeqiNP_001272427.1, NM_001285498.1
NP_035695.1, NM_011565.2
XP_006540840.1, XM_006540777.2

3D structure databases

SMRiP48301
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi204099, 3 interactors
CORUMiP48301
IntActiP48301, 1 interactor
STRINGi10090.ENSMUSP00000103431

PTM databases

iPTMnetiP48301
PhosphoSitePlusiP48301

Proteomic databases

PaxDbiP48301
PRIDEiP48301
ProteomicsDBi259369

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		31984, 259 antibodies from 33 providers

The DNASU plasmid repository

More...DNASUi		21677

Genome annotation databases

EnsembliENSMUST00000033060; ENSMUSP00000033060; ENSMUSG00000030796
ENSMUST00000107801; ENSMUSP00000103431; ENSMUSG00000030796
GeneIDi21677
KEGGimmu:21677
UCSCiuc009gud.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		8463
MGIiMGI:104904, Tead2
VEuPathDBiHostDB:ENSMUSG00000030796

Phylogenomic databases

eggNOGiKOG3841, Eukaryota
GeneTreeiENSGT00950000182956
HOGENOMiCLU_012515_2_0_1
InParanoidiP48301
OMAiWQTRALG
OrthoDBi823827at2759
PhylomeDBiP48301
TreeFamiTF313443

Enzyme and pathway databases

ReactomeiR-MMU-2032785, YAP1- and WWTR1 (TAZ)-stimulated gene expression
R-MMU-8951671, RUNX3 regulates YAP1-mediated transcription

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		21677, 6 hits in 63 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Tead2, mouse

Protein Ontology

More...PROi		PR:P48301
RNActiP48301, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000030796, Expressed in hindlimb bud and 127 other tissues
GenevisibleiP48301, MM

Family and domain databases

Gene3Di6.10.20.40, 1 hit
InterProiView protein in InterPro
IPR000818, TEA/ATTS_dom
IPR038096, TEA/ATTS_sf
IPR016361, TEF_metazoa
IPR041086, YBD
PfamiView protein in Pfam
PF01285, TEA, 1 hit
PF17725, YBD, 1 hit
PIRSFiPIRSF002603, TEF, 1 hit
PRINTSiPR00065, TEADOMAIN
SMARTiView protein in SMART
SM00426, TEA, 1 hit
PROSITEiView protein in PROSITE
PS00554, TEA_1, 1 hit
PS51088, TEA_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTEAD2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P48301
Secondary accession number(s): Q62297
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: February 23, 2022
This is version 158 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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