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Protein

Protein RecA

Gene

recA

Organism
Thermus aquaticus
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi65 – 72ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA damage, DNA recombination, DNA repair, SOS response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RecAUniRule annotation
Alternative name(s):
Recombinase AUniRule annotation
Gene namesi
Name:recAUniRule annotation
OrganismiThermus aquaticus
Taxonomic identifieri271 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001228791 – 340Protein RecAAdd BLAST340

Interactioni

Protein-protein interaction databases

DIPiDIP-61165N

Structurei

3D structure databases

ProteinModelPortaliP48296
SMRiP48296
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C68 Bacteria
COG0468 LUCA

Family and domain databases

CDDicd00983 recA, 1 hit
Gene3Di3.30.250.10, 1 hit
HAMAPiMF_00268 RecA, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR013765 DNA_recomb/repair_RecA
IPR020584 DNA_recomb/repair_RecA_CS
IPR027417 P-loop_NTPase
IPR020588 RecA_ATP-bd
IPR023400 RecA_C
IPR020587 RecA_monomer-monomer_interface
PANTHERiPTHR22942:SF1 PTHR22942:SF1, 1 hit
PfamiView protein in Pfam
PF00154 RecA, 1 hit
PRINTSiPR00142 RECA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF54752 SSF54752, 1 hit
TIGRFAMsiTIGR02012 tigrfam_recA, 1 hit
PROSITEiView protein in PROSITE
PS00321 RECA_1, 1 hit
PS50162 RECA_2, 1 hit
PS50163 RECA_3, 1 hit

Sequencei

Sequence statusi: Complete.

P48296-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEENKRKSLE NALKTIEKEF GKGAVMRLGE MPKLQVDVIP TGSLGLDLAL
60 70 80 90 100
GIGGIPRGRV TEIFGPESGG KTTLALTIIA QAQKGGGVAA FVDAEHALDP
110 120 130 140 150
LYAKKLGVDV QELLVSQPDT GEQALEIVEL LARSGAVDVI VVDSVAALVP
160 170 180 190 200
KAEIEGEMGD QHVGLQARLM SQALRKLTAV LSKSNTAAIF INQVREKVGV
210 220 230 240 250
MYGNPETTPG GRALKFYSSV RLDVRKSGQP IKVGNEAVGI KVKVKVVKNK
260 270 280 290 300
LAPPFREAEL EIYFGRGLDP VMDLVNVAVA AGVIEKAGSW FSYGEHRLGQ
310 320 330 340
GKEKAAEYLR ERPELLEEIR AKVLERADKV VLAAGEEEGE
Length:340
Mass (Da):36,454
Last modified:February 1, 1996 - v1
Checksum:i0411D8437623A7AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L20680 Unassigned DNA Translation: AAA19796.1
L20095 Genomic DNA Translation: AAA27502.1
PIRiA53378

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L20680 Unassigned DNA Translation: AAA19796.1
L20095 Genomic DNA Translation: AAA27502.1
PIRiA53378

3D structure databases

ProteinModelPortaliP48296
SMRiP48296
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-61165N

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4105C68 Bacteria
COG0468 LUCA

Family and domain databases

CDDicd00983 recA, 1 hit
Gene3Di3.30.250.10, 1 hit
HAMAPiMF_00268 RecA, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR013765 DNA_recomb/repair_RecA
IPR020584 DNA_recomb/repair_RecA_CS
IPR027417 P-loop_NTPase
IPR020588 RecA_ATP-bd
IPR023400 RecA_C
IPR020587 RecA_monomer-monomer_interface
PANTHERiPTHR22942:SF1 PTHR22942:SF1, 1 hit
PfamiView protein in Pfam
PF00154 RecA, 1 hit
PRINTSiPR00142 RECA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF54752 SSF54752, 1 hit
TIGRFAMsiTIGR02012 tigrfam_recA, 1 hit
PROSITEiView protein in PROSITE
PS00321 RECA_1, 1 hit
PS50162 RECA_2, 1 hit
PS50163 RECA_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRECA_THEAQ
AccessioniPrimary (citable) accession number: P48296
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: October 10, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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