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1 to 25 of 34  Show
  1. 1
    "Characterization of cytosolic malic enzyme in human tumor cells."
    Loeber G., Dworkin M.B., Infante A., Ahorn H.
    FEBS Lett. 344:181-186(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
    Category: Subcellular Location, Expression, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 5 other entries.

  2. 2
    "Cloning, sequencing and functional expression of a cDNA encoding a NADP-dependent malic enzyme from human liver."
    Gonzalez-Manchon C., Ferrer M., Ayuso M.S., Parrilla R.
    Gene 159:255-260(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY.
    Category: Expression, Sequences.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).
  3. 3
    "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Category: Sequences.
    Tissue: Testis.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 12927 other entries.

  4. 4
    Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S.
    Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  5. 5
    "The DNA sequence and analysis of human chromosome 6."
    Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
    Beck S.
    Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 3773 other entries.

  6. 6
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Category: Sequences.
    Tissue: Skin.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50448 other entries.

  7. 7
    "Nonidentity of the cDNA sequence of human breast cancer cell malic enzyme to that from the normal human cell."
    Chou W.Y., Huang S.M., Chang G.G.
    J. Protein Chem. 15:273-279(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 8-572 (ISOFORM 1).
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  8. 8
    "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 5354 and mapped to 17 other entries.

  9. 9
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 18117 other entries.

  10. 10
    "Crystal structure of a human malic enzyme."
    Structural genomics consortium (SGC)
    Submitted (MAR-2007) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 15-555.
    Category: Structure.
    Source: UniProtKB/Swiss-Prot (reviewed).
  11. 11
    "The interaction between microsomal epoxide hydrolase polymorphisms and cumulative cigarette smoking in different histological subtypes of lung cancer."
    Zhou W., Thurston S.W., Liu G., Xu L.L., Miller D.P., Wain J.C., Lynch T.J., Su L., Christiani D.C.
    Cancer Epidemiol. Biomarkers Prev. 10:461-466(2001) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator).
    Source: GeneRIF:4199.

    This publication is mapped to 3 other entries.

  12. 12
    "Structure and function of malic enzymes, a new class of oxidative decarboxylases."
    Chang G.G., Tong L.
    Biochemistry 42:12721-12733(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-400119.

    This publication is mapped to 1 other entry.

  13. 13
    "Determinants of the dual cofactor specificity and substrate cooperativity of the human mitochondrial NAD(P)+-dependent malic enzyme: functional roles of glutamine 362."
    Hsieh J.Y., Liu G.Y., Chang G.G., Hung H.C.
    J. Biol. Chem. 281:23237-23245(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: that the single mutation of Gln362 to Lys in human m-NAD-ME changes it to an NADP+-dependent enzyme which is characteristic because it is non-allosteric non-cooperative and NADP+-specific.
    Source: GeneRIF:4199.

    This publication is mapped to 3 other entries.

  14. 14
    "Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations."
    Lu Y., Dolle M.E., Imholz S., van 't Slot R., Verschuren W.M., Wijmenga C., Feskens E.J., Boer J.M.
    J. Lipid Res. 49:2582-2589(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: Observational study of gene-disease association. (HuGE Navigator). [GeneRIF:4199]. Not Associated with METABOLIC: plasma HDL cholesterol (HDL-C) levels. [GAD:590317].
    Source: GeneRIF:4199, GAD:590317.

    This publication is mapped to 1555 other entries.

  15. 15
    "Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion."
    Heart E., Cline G.W., Collis L.P., Pongratz R.L., Gray J.P., Smith P.J.
    Am. J. Physiol. Endocrinol. Metab. 296:E1354-62(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: although ME1 overexpression augments anaplerosis and glucose stimulated insulin secretion in INS-1 832/13 cells it is not likely involved in methyl succinate and glucose stimulated insulin secretion in pancreatic islets.
    Source: GeneRIF:4199.

    This publication is mapped to 12 other entries.

  16. 16
    "Malic enzyme in human liver. Intracellular distribution, purification and properties of cytosolic isozyme."
    Zelewski M., Swierczynski J.
    Eur. J. Biochem. 201:339-345(1991) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-400119.
  17. 17
    "Functional roles of the tetramer organization of malic enzyme."
    Hsieh J.Y., Chen S.H., Hung H.C.
    J. Biol. Chem. 284:18096-18105(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Family & Domains.
    Annotation: human c-NADP-ME exists mainly as a tetramer whereas human m-NAD(P)-ME exists as a mixture of dimers and tetramers.
    Source: GeneRIF:4199.

    This publication is mapped to 8 other entries.

  18. 18
    "Long-range interaction between the enzyme active site and a distant allosteric site in the human mitochondrial NAD(P)+-dependent malic enzyme."
    Hsieh J.Y., Su K.L., Ho P.T., Hung H.C.
    Arch. Biochem. Biophys. 487:19-27(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: A series of R98/D102 mutants examined the possible interactions between Arg98 and Asp102 using double-mutant cycle analysis. Kinetic analysis revealed that the catalytic efficiency of was severely affected by mutating both Arg98 and Asp102 residues.
    Source: GeneRIF:4199.

    This publication is mapped to 3 other entries.

  19. 19
    "Comparative analysis of gene regulation by the transcription factor PPARalpha between mouse and human."
    Rakhshandehroo M., Hooiveld G., Muller M., Kersten S.
    PLoS ONE 4:e6796-e6796(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-400119.

    This publication is mapped to 89 other entries.

  20. 20
    Category: Function.
    Annotation: Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:4199.

    This publication is mapped to 3063 other entries.

  21. 21
    "The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle."
    Warnatz H.J., Schmidt D., Manke T., Piccini I., Sultan M., Borodina T., Balzereit D., Wruck W., Soldatov A., Vingron M., Lehrach H., Yaspo M.L.
    J. Biol. Chem. 286:23521-23532(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: ME1 is a functional target gene of the BACH1 transcription factor according to ChIP-seq and knockdown analysis in HEK 293 cells.
    Source: GeneRIF:4199.

    This publication is mapped to 201 other entries.

  22. 22
    "Malic enzyme gene polymorphism is associated with responsiveness in circulating parathyroid hormone after long-term calcium supplementation."
    Chailurkit L., Chanprasertyothin S., Charoenkiatkul S., Krisnamara N., Rajatanavin R., Ongphiphadhanakul B.
    J Nutr Health Aging 16:246-251(2012) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: cytosolic malic enzyme 1 gene polymorphism is associated with the degree of suppression of parathyroid hormone after long-term calcium supplementation; the effect is probably mediated through an increase in intestinal calcium absorption.
    Source: GeneRIF:4199.

    This publication is mapped to 3 other entries.

  23. 23
    "Repressing malic enzyme 1 redirects glucose metabolism, unbalances the redox state, and attenuates migratory and invasive abilities in nasopharyngeal carcinoma cell lines."
    Zheng F.J., Ye H.B., Wu M.S., Lian Y.F., Qian C.N., Zeng Y.X.
    Chin J Cancer 31:519-531(2012) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: essential role for ME1 in the production of cytosolic NADPH and maintenance of migratory and invasive abilities of nasopharyngeal carcinoma cells.
    Source: GeneRIF:4199.

    This publication is mapped to 3 other entries.

  24. 24
    "Biophysical characterization of the dimer and tetramer interface interactions of the human cytosolic malic enzyme."
    Murugan S., Hung H.C.
    PLoS ONE 7:e50143-e50143(2012) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Structure, Family & Domains.
    Annotation: Pathway. [Reactome:R-HSA-400119]. the differential protein stability between dimer and tetramer interface interactions of human c-NADP-ME. [GeneRIF:4199].
    Source: GeneRIF:4199, Reactome:R-HSA-400119.

    This publication is mapped to 3 other entries.

  25. 25
    "Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence."
    Jiang P., Du W., Mancuso A., Wellen K.E., Yang X.
    Nature 493:689-693(2013) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: p53 represses the expression of the tricarboxylic-acid-cycle-associated malic enzymes ME1 and ME2 in human and mouse cells.
    Source: GeneRIF:4199.

    This publication is mapped to 26 other entries.

1 to 25 of 34  Show
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