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Entry version 157 (13 Feb 2019)
Sequence version 2 (25 Nov 2008)
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Protein

Neuropeptides B/W receptor type 1

Gene

NPBWR1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • G protein-coupled receptor activity Source: GO_Central
  • neuropeptide binding Source: GO_Central
  • neuropeptide receptor activity Source: InterPro
  • opioid receptor activity Source: ProtInc
  • peptide binding Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionG-protein coupled receptor, Receptor, Transducer

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-375276 Peptide ligand-binding receptors
R-HSA-418594 G alpha (i) signalling events

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Neuropeptides B/W receptor type 1
Alternative name(s):
G-protein coupled receptor 7
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NPBWR1
Synonyms:GPR7
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000183729.3

Human Gene Nomenclature Database

More...
HGNCi
HGNC:4522 NPBWR1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
600730 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P48145

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 37ExtracellularSequence analysisAdd BLAST37
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei38 – 61Helical; Name=1Sequence analysisAdd BLAST24
Topological domaini62 – 72CytoplasmicSequence analysisAdd BLAST11
Transmembranei73 – 97Helical; Name=2Sequence analysisAdd BLAST25
Topological domaini98 – 112ExtracellularSequence analysisAdd BLAST15
Transmembranei113 – 132Helical; Name=3Sequence analysisAdd BLAST20
Topological domaini133 – 157CytoplasmicSequence analysisAdd BLAST25
Transmembranei158 – 177Helical; Name=4Sequence analysisAdd BLAST20
Topological domaini178 – 202ExtracellularSequence analysisAdd BLAST25
Transmembranei203 – 224Helical; Name=5Sequence analysisAdd BLAST22
Topological domaini225 – 248CytoplasmicSequence analysisAdd BLAST24
Transmembranei249 – 273Helical; Name=6Sequence analysisAdd BLAST25
Topological domaini274 – 283ExtracellularSequence analysis10
Transmembranei284 – 298Helical; Name=7Sequence analysisAdd BLAST15
Topological domaini299 – 328CytoplasmicSequence analysisAdd BLAST30

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
2831

Open Targets

More...
OpenTargetsi
ENSG00000183729

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA28912

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL1293293

IUPHAR/BPS Guide to PHARMACOLOGY

More...
GuidetoPHARMACOLOGYi
303

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
NPBWR1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
215274092

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000695181 – 328Neuropeptides B/W receptor type 1Add BLAST328

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi3N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi13N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi25N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi109 ↔ 188PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P48145

PeptideAtlas

More...
PeptideAtlasi
P48145

PRoteomics IDEntifications database

More...
PRIDEi
P48145

ProteomicsDB human proteome resource

More...
ProteomicsDBi
55864

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P48145

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Found in cerebellum and frontal cortex. Detected at high levels in hippocampus, amygdala and trachea; at moderate levels in fetal brain, pituitary gland and prostate. Not in caudate, accumbens, kidney or liver. Also detected at high levels in lung carcinoma.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000183729 Expressed in 19 organ(s), highest expression level in temporal lobe

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P48145 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P48145 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
109092, 2 interactors

Protein interaction database and analysis system

More...
IntActi
P48145, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000330284

Chemistry databases

BindingDB database of measured binding affinities

More...
BindingDBi
P48145

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P48145

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P48145

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3656 Eukaryota
ENOG410XRW9 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161936

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000230485

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG106919

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P48145

KEGG Orthology (KO)

More...
KOi
K05268

Identification of Orthologs from Complete Genome Data

More...
OMAi
QLDSHAK

Database of Orthologous Groups

More...
OrthoDBi
1011272at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P48145

TreeFam database of animal gene trees

More...
TreeFami
TF315737

Family and domain databases

Conserved Domains Database

More...
CDDi
cd15087 7tmA_NPBWR, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR009150 Neuropept_B/W_rcpt
IPR027348 NPBW1

The PANTHER Classification System

More...
PANTHERi
PTHR24229:SF47 PTHR24229:SF47, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00001 7tm_1, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00237 GPCRRHODOPSN
PR01855 NRPEPTIDEWR

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P48145-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDNASFSEPW PANASGPDPA LSCSNASTLA PLPAPLAVAV PVVYAVICAV
60 70 80 90 100
GLAGNSAVLY VLLRAPRMKT VTNLFILNLA IADELFTLVL PINIADFLLR
110 120 130 140 150
QWPFGELMCK LIVAIDQYNT FSSLYFLTVM SADRYLVVLA TAESRRVAGR
160 170 180 190 200
TYSAARAVSL AVWGIVTLVV LPFAVFARLD DEQGRRQCVL VFPQPEAFWW
210 220 230 240 250
RASRLYTLVL GFAIPVSTIC VLYTTLLCRL HAMRLDSHAK ALERAKKRVT
260 270 280 290 300
FLVVAILAVC LLCWTPYHLS TVVALTTDLP QTPLVIAISY FITSLSYANS
310 320
CLNPFLYAFL DASFRRNLRQ LITCRAAA
Length:328
Mass (Da):36,103
Last modified:November 25, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7A90F85AD64A3980
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti296S → T in AAC50197 (PubMed:7590751).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03576519P → Q in a breast cancer sample; somatic mutation. 1 PublicationCorresponds to variant dbSNP:rs772418985Ensembl.1
Natural variantiVAR_047788135Y → F. Corresponds to variant dbSNP:rs33977775Ensembl.1
Natural variantiVAR_047789319R → C. Corresponds to variant dbSNP:rs36068168Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U22491 Genomic DNA Translation: AAC50197.1
CH471068 Genomic DNA Translation: EAW86722.1
BC069117 mRNA Translation: AAH69117.1
BC107101 mRNA Translation: AAI07102.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS6151.1

Protein sequence database of the Protein Information Resource

More...
PIRi
I38973

NCBI Reference Sequences

More...
RefSeqi
NP_005276.2, NM_005285.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.248117

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000331251; ENSP00000330284; ENSG00000183729

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2831

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:2831

UCSC genome browser

More...
UCSCi
uc011ldu.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U22491 Genomic DNA Translation: AAC50197.1
CH471068 Genomic DNA Translation: EAW86722.1
BC069117 mRNA Translation: AAH69117.1
BC107101 mRNA Translation: AAI07102.1
CCDSiCCDS6151.1
PIRiI38973
RefSeqiNP_005276.2, NM_005285.3
UniGeneiHs.248117

3D structure databases

ProteinModelPortaliP48145
SMRiP48145
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi109092, 2 interactors
IntActiP48145, 1 interactor
STRINGi9606.ENSP00000330284

Chemistry databases

BindingDBiP48145
ChEMBLiCHEMBL1293293
GuidetoPHARMACOLOGYi303

Protein family/group databases

Information system for G protein-coupled receptors (GPCRs)

More...
GPCRDBi
Search...

PTM databases

PhosphoSitePlusiP48145

Polymorphism and mutation databases

BioMutaiNPBWR1
DMDMi215274092

Proteomic databases

PaxDbiP48145
PeptideAtlasiP48145
PRIDEiP48145
ProteomicsDBi55864

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000331251; ENSP00000330284; ENSG00000183729
GeneIDi2831
KEGGihsa:2831
UCSCiuc011ldu.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
2831
DisGeNETi2831
EuPathDBiHostDB:ENSG00000183729.3

GeneCards: human genes, protein and diseases

More...
GeneCardsi
NPBWR1

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0034348
HGNCiHGNC:4522 NPBWR1
MIMi600730 gene
neXtProtiNX_P48145
OpenTargetsiENSG00000183729
PharmGKBiPA28912

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00940000161936
HOGENOMiHOG000230485
HOVERGENiHBG106919
InParanoidiP48145
KOiK05268
OMAiQLDSHAK
OrthoDBi1011272at2759
PhylomeDBiP48145
TreeFamiTF315737

Enzyme and pathway databases

ReactomeiR-HSA-375276 Peptide ligand-binding receptors
R-HSA-418594 G alpha (i) signalling events

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
Neuropeptides_B/W_receptor_1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
2831

Protein Ontology

More...
PROi
PR:P48145

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000183729 Expressed in 19 organ(s), highest expression level in temporal lobe
ExpressionAtlasiP48145 baseline and differential
GenevisibleiP48145 HS

Family and domain databases

CDDicd15087 7tmA_NPBWR, 1 hit
InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR009150 Neuropept_B/W_rcpt
IPR027348 NPBW1
PANTHERiPTHR24229:SF47 PTHR24229:SF47, 1 hit
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR01855 NRPEPTIDEWR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNPBW1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P48145
Secondary accession number(s): Q6NTC7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: November 25, 2008
Last modified: February 13, 2019
This is version 157 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  6. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
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