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Protein

60S ribosomal protein L6

Gene

rpl-6

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the large ribosomal subunit.By similarity

GO - Molecular functioni

GO - Biological processi

  • cytoplasmic translation Source: GO_Central
  • determination of adult lifespan Source: WormBase
  • ribosomal large subunit assembly Source: GO_Central

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-CEL-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-CEL-1799339 SRP-dependent cotranslational protein targeting to membrane
R-CEL-72689 Formation of a pool of free 40S subunits
R-CEL-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-CEL-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-CEL-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L6
Gene namesi
Name:rpl-6
ORF Names:R151.3
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiR151.3 ; CE00744 ; WBGene00004417 ; rpl-6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001710131 – 21760S ribosomal protein L6Add BLAST217

Proteomic databases

EPDiP47991
PaxDbiP47991
PeptideAtlasiP47991
PRIDEiP47991

PTM databases

iPTMnetiP47991

Expressioni

Gene expression databases

BgeeiWBGene00004417

Interactioni

Subunit structurei

Component of the large ribosomal subunit (By similarity). May bind IPO9 with low affinity (By similarity).By similarity

Binary interactionsi

WithEntry#Exp.IntActNotes
let-756Q111843EBI-316106,EBI-3843983

Protein-protein interaction databases

BioGridi41227, 8 interactors
DIPiDIP-26565N
IntActiP47991, 8 interactors
STRINGi6239.R151.3.1

Structurei

3D structure databases

ProteinModelPortaliP47991
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1694 Eukaryota
COG2163 LUCA
GeneTreeiENSGT00390000003682
HOGENOMiHOG000207317
InParanoidiP47991
KOiK02934
OMAiRKGDKPH
OrthoDBiEOG091G0L13
PhylomeDBiP47991

Family and domain databases

Gene3Di2.30.30.30, 1 hit
InterProiView protein in InterPro
IPR000915 60S_ribosomal_L6E
IPR014722 Rib_L2_dom2
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR10715 PTHR10715, 1 hit
PfamiView protein in Pfam
PF01159 Ribosomal_L6e, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
PROSITEiView protein in PROSITE
PS01170 RIBOSOMAL_L6E, 1 hit

Sequencei

Sequence statusi: Complete.

P47991-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVGKRNLPVI SRNFDLSPGV LRFSASRLRL KKGEKKPKFT KDTSAKLPKL
60 70 80 90 100
QRNGTKFALG HSKTVTLRKT LTPGTVLIVL AGRHKGKRVV FLKQLPQSGL
110 120 130 140 150
LLVTGPHKIN GFPLRRIGQA FVIATSLKVN VSGVKIPEHI NDEYFKRKST
160 170 180 190 200
AQKTGKNIFA SGKTEYTVSE QRKKDIKTVD APILAAIKKH PEHKFLFGYL
210
GTRFSLGKNQ YPHKMQF
Length:217
Mass (Da):24,313
Last modified:February 1, 1996 - v1
Checksum:i5BA7FE473B1C239B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081317 Genomic DNA Translation: CCD70755.1
PIRiT16762
RefSeqiNP_498584.1, NM_066183.3
UniGeneiCel.8890

Genome annotation databases

EnsemblMetazoaiR151.3.1; R151.3.1; WBGene00004417
R151.3.2; R151.3.2; WBGene00004417
R151.3.3; R151.3.3; WBGene00004417
R151.3.4; R151.3.4; WBGene00004417
GeneIDi176015
KEGGicel:CELE_R151.3
UCSCiR151.3.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiRL6_CAEEL
AccessioniPrimary (citable) accession number: P47991
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: February 1, 1996
Last modified: July 18, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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