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Protein

60S ribosomal protein L13

Gene

Rpl13

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L13
Alternative name(s):
A52
Gene namesi
Name:Rpl13
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:105922 Rpl13

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001929201 – 21160S ribosomal protein L13Add BLAST211

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei16N6-acetyllysineBy similarity1
Modified residuei52PhosphoserineBy similarity1
Modified residuei77PhosphoserineBy similarity1
Modified residuei106PhosphoserineCombined sources1
Cross-linki123Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki145Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki174Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateBy similarity
Cross-linki174Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity
Modified residuei177N6-acetyllysine; alternateBy similarity1
Cross-linki177Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiP47963
MaxQBiP47963
PaxDbiP47963
PeptideAtlasiP47963
PRIDEiP47963

PTM databases

iPTMnetiP47963
PhosphoSitePlusiP47963
SwissPalmiP47963

Expressioni

Gene expression databases

BgeeiENSMUSG00000000740
CleanExiMM_RPL13
GenevisibleiP47963 MM

Interactioni

Protein-protein interaction databases

BioGridi234761, 3 interactors
CORUMiP47963
IntActiP47963, 8 interactors
MINTiP47963
STRINGi10090.ENSMUSP00000000756

Structurei

3D structure databases

ProteinModelPortaliP47963
SMRiP47963
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3295 Eukaryota
COG4352 LUCA
GeneTreeiENSGT00390000007818
HOGENOMiHOG000170452
HOVERGENiHBG001156
InParanoidiP47963
KOiK02873
OMAiIVVDHRR
OrthoDBiEOG091G0KGO
PhylomeDBiP47963
TreeFamiTF300073

Family and domain databases

HAMAPiMF_00499 Ribosomal_L13e, 1 hit
InterProiView protein in InterPro
IPR001380 Ribosomal_L13e
IPR018256 Ribosomal_L13e_CS
PANTHERiPTHR11722 PTHR11722, 1 hit
PfamiView protein in Pfam
PF01294 Ribosomal_L13e, 1 hit
PROSITEiView protein in PROSITE
PS01104 RIBOSOMAL_L13E, 1 hit

Sequencei

Sequence statusi: Complete.

P47963-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPSRNGMIL KPHFHKDWQQ RVDTWFNQPA RKIRRRKARQ AKARRIAPRP
60 70 80 90 100
ASGPIRPIVR CPTVRYHTKV RAGRGFSLEE LRVAGIHKKV ARTIGISVDP
110 120 130 140 150
RRRNKSTESL QANVQRLKEY RSKLILFPRK PSAPKKGDSS AEELKLATQL
160 170 180 190 200
TGPVMPIRNV YKKEKARVIT EEEKNFKAFA SLRMARANAR LFGIRAKRAK
210
EAAEQDVEKK K
Length:211
Mass (Da):24,305
Last modified:January 23, 2007 - v3
Checksum:i27B1D4B97A9A1B74
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti40Q → L in AAA69923 (Ref. 1) Curated1
Sequence conflicti190 – 196RLFGIRA → PTLWQSEQ in AAA69923 (Ref. 1) Curated7
Sequence conflicti203 – 211AEQDVEKKK → SEQRCWKRKN in AAA69923 (Ref. 1) Curated9

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28917 mRNA Translation: AAA69923.1
AK002787 mRNA Translation: BAB22358.1
AK010989 mRNA Translation: BAB27309.1
BC055358 mRNA Translation: AAH55358.1
CCDSiCCDS22747.1
RefSeqiNP_058018.2, NM_016738.5
UniGeneiMm.319719
Mm.391834

Genome annotation databases

EnsembliENSMUST00000000756; ENSMUSP00000000756; ENSMUSG00000000740
GeneIDi270106
KEGGimmu:270106
UCSCiuc009nue.2 mouse

Similar proteinsi

Entry informationi

Entry nameiRL13_MOUSE
AccessioniPrimary (citable) accession number: P47963
Secondary accession number(s): Q9CRZ9, Q9DCH1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1996
Last sequence update: January 23, 2007
Last modified: June 20, 2018
This is version 140 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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